Cent Dix Ans de Renouvellements Incessants

During its hundred and ten years of existence the Revue de synthèse has experienced various periods each characterized by specific predilections, actions and modes of publication. Throughout this long journey, it has remained a place of reference for historiographical reflection and for dialogue between the sciences. It has also been a stimulus for intellectual history, history of science and epistemology. The article traces this route and provides relevant keys for today.