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The Growth Cone as Seen Through Cajal's Original Histological Preparations and Publications
Authors:Virginia García-Marín  Pablo García-López  Miguel Freire
Institution:1. Museum Cajal , Instituto Cajal, CSIC , 28002, Madrid, Spain vgmarin@cajal.csic.es;3. Museum Cajal , Instituto Cajal, CSIC , 28002, Madrid, Spain
Abstract:Abstract

Multiple sclerosis (MS) was first presented in a clinical setting in 1838. In this paper the presentation and treatment of a transient hemiparesis in a drummer in 1789 is discussed. This may have been an early case of MS and presents evidence against the theory that MS is an infectious disease beginning in the 19th century.
Keywords:growth cone  Cajal  original histological preparations  Golgi-impregnation  reduced silver nitrate method
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