Origins of the Creutzfeldt and Jakob Concept |
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Authors: | Serge Duckett Jan Stern |
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Institution: | London Neurological Centre , 110 Harley Street, London, W1N 1AF, UK |
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Abstract: | A review of the publications of Hans Creutzfeldt and Alfons Jakob pertaining to the concept which bears their name (CJD) reveals that they described a neuropathological syndrome and were opposed to its classi- fication as a neurological disease. The evidence on which Creutzfeldt and Jakob based their view is reevaluated, and studies by other workers are cited in which a range of environmental and genetic factors generated the CJ syndrome, challenging the proposition that CJD is a disease with a single cause.. |
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Keywords: | Associationism psychobiology Hartley Aristotle connectionism Newton 18th century England British empiricism vibration theory vibratiuncles |
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