Aspartic acid racemization variability in ancient human remains: implications in the prediction of ancient DNA recovery |
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Authors: | E. Ferná ndez,J.E. Ortiz,A. Pé rez-Pé rez,E. Prats,D. Turbó n,T. Torres,E. Arroyo-Pardo |
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Affiliation: | 1. Forensic Genetics and Population Genetics Laboratory, Department of Toxicology and Health Legislation, Faculty of Medicine, Complutense University of Madrid, Spain;2. Biomolecular Stratigraphy Laboratory, Department of Geological Engineering, Mines Engineering School, Polytechnic University of Madrid, Spain;3. Anthropology Section, Department of Animal Biology, University of Barcelona, Spain;4. Molecular Biology Institute of Barcelona, CSIC, Spain |
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Abstract: | The extent of racemization of aspartic acid (Asp) – expressed as d/l ratio – has been used as a marker of biomolecular degradation in ancient remains. However, Asp racemization rate is highly variable, and depends on biochemical and geochemical factors. In this paper we aim to determine to which extent the fraction analyzed and the kind of sample used may influence the d/l Asp ratios. Other factors, such as burial site and sample preservation conditions, are also considered. |
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Keywords: | Racemization Aspartic acid Ancient DNA Preservation Collagen |
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