Linking Bone Changes in the Distal Femur to Functional Deficits

Knee osteoarthritis (OA) is a condition that leads to functional deficits in the afflicted. Quantifying these deficits in a clinical population and relating them to bone changes in the distal femur is crucial to identifying potential impairment in archaeological populations. This study provides a hybrid knee OA grading system linking MRI observations of clinical populations and direct bone observations on skeletal populations. This system is then related to 28 pain, disability, and activity limitation outcome variables provided by the OA Initiative through frequency distributions, probability profiles, and Spearman's rank correlations. The results suggest that while the five outcome variables with the highest probabilities were common to males and females, bone changes in knee OA impact males and females differently. Copyright © 2012 John Wiley & Sons, Ltd.     

Further aspects of fur trade life depicted in the skeleton

Osteobiographies were reconstructed from the skeletal remains of four adults from Fort Edmonton, a 19th century trading post of the Canadian fur trade. Three males were Caucasoid and probably ethnic Scots, given the usual origin of fur traders in this region. The lone adult female in the sample was Mongoloid, either Indian or Métis, and likely the ‘country wife’ of a fur trader, since she was buried in the European tradition in the fort cemetery. The cause of death is not discernible from any of the skeletal remains and none of these individuals exhibit any evidence of chronic infectious disease, malnutrition or neoplasia. Trauma, arthritis and other indicators of physical stress do appear, however, and present an opportunity to expand our understanding of the effects of fur trade life on the skeleton. Viewed in the context of historical accounts of life at the fort in the early 19th century, stress markers on the skeletons of three males have led to the conclusion that they were voyageurs who engaged in trading trips by canoe or boat. Lesions of the capsule attachment area at the proximal tibio‐fibular articulation appear unilaterally in two males and may be associated with ‘mushing’ or driving a dog sled in winter. The musculoskeletal lesions on the one preserved female skeleton are consistent with the arduous domestic activities documented at the fort, which include milking cows, churning butter, stirring lye soap, and harvesting grain and root vegetables by hand. Since specific occupations or behaviours cannot be precisely determined from muscular attachment and other stress markers, these interpretations are made cautiously and only in the culture‐historical context of the skeletal sample. Copyright © 1999 John Wiley & Sons, Ltd.     

Variation in health and socioeconomic status within the W. Montague Cobb skeletal collection: Degenerative joint disease,trauma and cause of death

This paper examines health differences between two distinct samples within an African American skeletal population by investigating variation in osteoarthritis (OA) patterns, the presence of enthesopathies, fractures and cause of death. Surveys and statistical treatments tested the hypothesis that two samples within a population that have different socioeconomic contexts will present associated differences in health. Binomial statistics were used to examine differences in OA patterns and prevalence within and between groups, and according to age and sex. These data were paired with information on the presence of enthesopathies at select muscle attachment and insertion sites to add another dimension to the assessment of mechanical strain. Finally causes of death, when available, were recorded to compare leading causes within and between samples, as well as with the larger population. Data reveal significant differences in the prevalence of OA between groups. Significant differences also presented when comparing the prevalence of unilateral and bilateral affect. Although a number of differences in health status observed can be attributed to age, relationships between the presence of OA and enthesopathies in a portion of the sample indicates that degenerative change and hypertrophy in the samples reflect both systemic and non‐systemic change. The presence and pattern of fractures and causes of death are also suggestive of differences in social context between the two samples. Copyright © 2010 John Wiley & Sons, Ltd.     

A simple method for calculating the prevalence of disease in a past human population

A simple method for calculating the prevalence of disease in a past human population is described with particular reference to osteoarthritis. It can be applied to diseases other than osteoarthritis, and should prove particularly useful when studying the epidemiology of other diseases which affect numerous sites within the body and where the overall prevalence cannot be obtained simply by adding the prevalences of the individual sites, because more than one may be affected in the same skeleton. Copyright © 2004 John Wiley & Sons, Ltd.     

The Cost of a Commute: A Multidisciplinary Approach to Osteoarthritis in New Kingdom Egypt

This article evaluates rates of osteoarthritis of the lower limb in human remains from Deir el‐Medina in order to compare the health of the residents of Deir el‐Medina with previous studies on other ancient Egyptian and Nubian populations. This study focuses on osteological observations from the commingled New Kingdom human remains documented during the 2012–2014 field seasons of the Institut Français d'Archéologie Orientale. This is the first publication of osteoarthritis for the human remains at Deir el‐Medina, a dataset which complements comparable populations at sites such as Amarna, Giza, and Tombos. It demonstrates that men in the village of Deir el‐Medina experienced significantly higher rates of osteoarthritis in the ankle and knee in comparison to women at Deir el‐Medina. Rates of osteoarthritis in the lower limb at Deir el‐Medina generally fall between workers' cemeteries and middle‐class or elite cemeteries. This study also includes data from Deir el‐Medina's detailed textual record and intact landscape in order to determine how occupation influenced these higher rates of osteoarthritis. The duration, intensity, and frequency of the workmen's hikes are reconstructed based on the surrounding landscape and 42 texts recording work days. This study compares rates of osteoarthritis with these datasets in order to document how the strain, duration, and frequency of the workmen's hikes may have impacted overall rates of osteoarthritis. Consequently, data from the texts and landscape surrounding Deir el‐Medina not only corroborate osteoarthritis patterns, but offer detailed daily life activity which can be used as a comparison for broader studies on osteoarthritis in ancient and modern populations. Copyright © 2016 John Wiley & Sons, Ltd.     

Paleopathology of The Population of Krasnoyarsk,Central Siberia (Pokrovskiy and Voskresensko-Preobrazhenskiy Cemeteries of the 17th– Early 20th Centuries)

Published data on the paleopathology of Siberian populations are scarce. However, two samples of adult and non- adult skeletons taken from excavations at the Pokrovskiy (17th–18th centuries) and Voskresensko-Preobrazhenskiy (17th–early 20th century) cemeteries in Krasnoyarsk (123 and 204; 101 and 81, respectively) revealed cases of rickets, tuberculosis, and congenital syphilis in children, and vertebral tuberculosis and tertiary syphilis in adults. Trauma areas included ribs, hands, forearms, and tibiae. These two samples provide evidence on which to base an assessment of the health of the Krasnoyarsk population from 1628 to the early 1900s.     

Osteoarthritis revisited: a contemporary review of aetiology

Osteoarthritis is among the most common pathological conditions in skeletal collections and is the most frequent musculoskeletal disorder in contemporary populations. Jurmain ( 1991 ) has previously published in this journal a brief review of skeletal perspectives on osteoarthritis. Subsequent studies by osteologists and medical researchers have added considerably to understanding of the aetiology and patterning of osteoarthritis. Thus, it is timely to present an updated review that expands and supports conclusions discussed in the earlier review. In short, osteoarthritis aetiology is multifactorial, with age being the main influence on the onset and severity of osteoarthritis. Genetic influences also play a large role in the severity of osteoarthritis, especially in the lower limbs. Weight, although playing a significant role for modern populations, seems to have had very minimal effects on prehistoric populations. Sex differences may often be a consequence of hormones, body size and anatomy, rather than activity related. Finally, intense activity starting at a young age still may influence osteoarthritis, especially in the upper limbs. Future directions discussed include within‐body comparisons, animal studies, and examining patterns in large populations. Copyright © 2007 John Wiley & Sons, Ltd.     

Slipped proximal femoral epiphysis in a priest from the medieval period

During the course of a routine analysis of a cemetery burial population associated with the medieval hospital of St Giles, Brough, North Yorkshire, the partially excavated burial (No. 1423) of a priest, as identified through the associated chalice and paten dating to the medieval period, was observed to exhibit osseous changes commensurate with those of an untreated slipped proximal femoral epiphysis. Secondary osseous changes were noted that may indicate habitual positional behaviour subsequent to the injury.     

Skeletal markers of occupational stress in the Fur Trade: A case study from a Hudson's Bay Company Fur Trade post

The Seafort Burial Site (FcPr100) is a Fur Trade Period cemetery located near the town of Rocky Mountain House, Alberta. The results of recent analysis of skeletons recovered during salvage excavations between 1969 and 1971 suggest that three males in this sample were voyageurs in the employ of the Hudson's Bay Company. Vertebral osteophytosis and osteoarthritis, Schmorl's nodes, muscle origin robusticity and new bone formation at entheses and syndesmoses, and osteoarthritis at the elbow and shoulder joints provide evidence for carrying, lifting, and paddling or rowing. The presence of accessory sacral facets also may be stress-related. In addition, the development of accessory articular facets on the metatarsals and proximal pedal phalanges may indicate activity-induced stress from hyperdorsiflexion of the toes in habitual kneeling, such as when river canoeing.