Cleft Lip Case in a Middle Bronze Age Young Man from Altai,Russia

Oral cleft (OC) is a common congenital anomaly in humans, which occurs in approximately one per 700 live births. However, cleft skulls are found relatively seldom in archaeological specimens, especially for the bc period. Mortality of infants with OC was apparently high because of breastfeeding difficulties and culturally sanctioned rejection of them in the past. This paper presents one of the most ancient cases of OC in Eurasia. The finding comes from the Middle Bronze Age pastoralists' cemetery in Altai, Russia. The skeletal remains have been radiocarbon dated to 1883–1665 cal bc . Cranial and dental measurements, computed tomography and radiography have been used to examine this malformation. The facial sculpting reconstruction has been performed to visualise the ante mortem appearance of the cleft face. Besides, δ¹³C and δ¹⁵N isotope analysis was used for a comparative study of the diet of the cleft individual. It has been established that a young man from Altai was affected by complete bilateral cleft lip and alveolus, which is a very rare form of typical OC. This defect is associated with dental anomalies such as hypodontia, microdontia, and ectopia as well as with dysmorphology of the facial complex outside the cleft area, including mild hypertelorism, hypoplasia of nasal bones and antheroposterior maxillary deficiency. Furthermore, aplasia of the frontal sinuses and the sacral spina bifida occulta have been observed. These findings are consistent with clinical data indicating strong correlation between development of a major defect and multiple minor anomalies. The results of the study also suggest that there was tolerant attitude towards the facial deformities among the ancient Altai pastoralists. Copyright © 2016 John Wiley & Sons, Ltd.     

Prehistoric radio‐ulnar synostosis: implications for function

Proximal radio‐ulnar synostosis (RUS) may occur congenitally, either as an isolated condition or as part of a syndrome, or it may occur as a secondary complication of forearm trauma. We provide a key for the differential diagnosis of congenital versus traumatic RUS, and for differentiation between types of congenital RUS. Congenital cases (CRUS) include absence of fracture, radial head abnormalities, radial shaft bowing, and absence of a sigmoid notch, whereas post‐traumatic RUS results from either radial neck fracture or evulsion of the biceps brachii, followed by ossification of the resulting haematoma or of the interosseous (IO) membrane. Congenital cases include those which result from incompetent differentiation of the single mesenchymal mass that gives rise to the radius and ulna (Type I) and those that result from radial head dislocation in utero, resulting usually from humeral or ulnar defects (Type II). Type II CRUS can be differentiated by the presence of radial overgrowth, among other factors. Following these guidelines, we describe and compare the morphology of three congenital cases from North America. Two present bony fusions and one a functional fusion with radial overgrowth. In each case, CRUS significantly limits both supination and pronation. Despite differences among the cases, several morphological accommodations are shared as a result of fixation in the neutral (semi‐pronated) position. These changes include the ventral migration of the IO crests of the ulnae and enlargement of the dorsal tubercles of the radius. Understanding the pattern of accommodations made in the face of compromised function ultimately increases our understanding of the patterns of growth in normal functional regimes. Copyright © 2000 John Wiley & Sons, Ltd.     

On the causes of perforations in archaeological domestic cattle skulls: New evidence

An example of ante‐mortem cranial perforations in the skull of a European wisent (Bison bonasus) from Armenia is presented. The implications for reinterpreting the possible causes of this condition in ancient domestic cattle (outlined in a previous paper) are briefly discussed. Copyright © 1999 John Wiley & Sons, Ltd.     

A portrait of the chief as a general paralytic: rhetorics of sexual pathology in the Parnell split*

The O’Shea trial and the ensuing fall of Charles Stewart Parnell occupy an epochal position in accounts of the sexual politics of Victorian Britain and the development of Irish nationalism. This article examines how the “Parnell myth” came to serve (and was constructed from the outset) as a symbolic edifice within which anxieties concerning the relationship between Irishness and sexuality could be foregrounded and negotiated. In particular, it will analyse Timothy Healy’s influential post-split denunciations of Parnell, and the rhetoric of sexual contagion through which they were conducted, a campaign which set the discursive terms of twentieth-century mainstream Irish nationalism. Through an analysis of Healy’s post-split journalism, contemporary political memoirs by T.P. O’Connor, and a range of nineteenth-century medical and psychiatric texts, this article will highlight the ways in which discourses of sexual health were used to reshape Parnell’s public persona at the level of gender and ethno-national affiliation. In doing so, it will illustrate how a sensitivity to the history of medicine can enrich critical understandings of a crucial moment in the political and cultural history of Ireland, and shed fresh light on the vexed collocation of Irish identity and sexual purity which the Parnell split reinforced.     

Congenital anomalies of the vertebral column: a case study on ancient and modern Egypt

The aim of this paper is to identify the frequency of congenital anomalies of the vertebral column in ancient Egyptians. The material for this study consisted of 272 skeletons excavated from Giza and belonging to the Old Kingdom (the time of the early pyramid builders). The vertebral columns of these skeletons were examined for the different types of congenital anomalies that affect the vertebrae. Nine cases (3.33%) were affected with spina bifida occulta, while six cases (2.22%) had transitional vertebrae at the lumbosacral joint. These frequencies are compared with other ancient populations. Copyright © 2006 John Wiley & Sons, Ltd.     

Sagittal Clefting of the Fifth Lumbar Vertebra of a Young Adult Female from Apollonia Pontica,Bulgaria

A rare congenital anomaly in the form of sagittal clefting of the fifth lumbar vertebra was observed in the skeleton of a young adult female excavated from the Greek colonial site of Apollonia Pontica (5th to 3rd centuries BC) on the Bulgarian Black Sea coast. No compensatory changes had occurred to the adjacent vertebrae, and no other skeletal anomalies or pathological conditions were observed in the skeleton. This anomaly, the first of its kind documented in ancient Greek remains, was likely asymptomatic and of no clinical significance. Copyright © 2012 John Wiley & Sons, Ltd.     

Anthropological analysis of the phenomenon of atlas occipitalisation exemplified by a skull from twardogóra (17th c.)—southern Poland

Occipitalisation of the atlas is one of the most frequent osseous anomalies of the atlas. It is characterised by the adhesion of the first cervical vertebra with the basilar part of the occipital bone. The most probable cause of the occipitalisation is a congenital disorder. The atlanto‐occipital fusion may lead to narrowing of the space for medulla oblongata, spinal cord and vertebral artery. This in turn may lead to many physiological symptoms. The skull from Twardogóra, Southern Poland, showed partial atlanto‐occipital fusion and presented an asymmetry in structure and shape of apertures for the vessels and nerves around the foramen magnum. Copyright © 2011 John Wiley & Sons, Ltd.     

Intracranial Arteriovenous Malformations as a Possible Cause of Endocranial Bone Lesions and Associated Neurological Disorder

Endocranial bone lesions have attracted intensive scientific debate on their aetiology. In recent literature, the lesions were almost exclusively interpreted as of infectious origin. In this paper, we give new insight into the aetiology of endocranial lesions, distinguishing the lesions of vascular origin from those caused by tuberculosis or other conditions. The analysis is based on a rare case of a young female individual who displayed multiple endocranial lesions with ‘serpens endocrania symmetrica’ morphology. The lesions were associated with an uncommon branching pattern of the middle meningeal artery and marked side differences in teeth pathology. Postcranial skeleton showed signs of the left upper limb weakness. The macroscopic finding of the endocranial lesions along with the skeletal evidence of neurological damage, together with characteristic radiological and histological features, can lead to diagnosis of arteriovenous malformations. This study aims to improve understanding of the aetiology of endocranial bone lesions. Copyright © 2012 John Wiley & Sons, Ltd.     

Probable Atretic Cephalocele in an Adult Female from Punta Secca (Sicily,Italy)

Excavations at Punta Secca, Sicily (Italy), in 2008 uncovered a substantially built tomb of ca ad 625/630 inside a private house and accompanying evidence for libations and funerary feasting in honour of the deceased. Inside the tomb were the skeletal remains of an adult female aged approximately 20/25 years and a child aged approximately 3/5 years. DNA analysis showed the child to be female and the adult and child to have been consanguineous. Archaeological and epigraphic evidence demonstrates that they were Christians. The cranium of the adult female showed an enlargement of the central portion of the occipital bone and a circular depression that terminated in a bifurcated foramen (diameter 3.25 mm). The former is likely an instance of occipital bunning; the latter is the first attested example of atretic cephalocele from an archaeological context. Tombs do not normally occur in ancient houses, and the hypothesis is advanced that the individual may have suffered from medical side effects, such as seizures, which caused rejection of the adult female by the local Christian community but veneration of her by her family as a holy woman. Copyright © 2012 John Wiley & Sons, Ltd.     

The Earliest Case of Spondylocarpotarsal Synostosis Syndrome (Roman Age—2nd Century ad)

Spondylocarpotarsal synostosis syndrome (SCT) is a rare genetic disease. It was described for the first time during the 1970s. The most relevant pathognomonic skeletal changes are vertebral malsegmentation and the fusion of the carpal and tarsal bones. This last implication can be absent in some cases. We have investigated a case of SCT in a female of about 40–45 years of age, dated to the 2nd century ad . This discovery is important for two reasons: first, SCT is not a recent disease but rather one with a very long history; second, the clinical picture of the skeletal changes (malsegmentation of some elements of the spine, fusion of carpal bones) seems not to have varied in the last 2000 years. Furthermore, the age of the Roman female shows medium–long survival in patients suffering from SCT, even in the absence of medical treatment. Copyright © 2011 John Wiley & Sons, Ltd.