Emigrated neuroscientists from Berlin to North America

ABSTRACT

The highest number of German scholars and physicians, forced by the National Socialist regime to emigrate for “race” or political reasons, were from Berlin. Language and medical exams were requested differently in their new host country—the United States—leading to a concentration of immigrants in the New York and Boston areas. Very early Emergency Committees in Aid of German Scholars and Physicians were established. Undergraduate students (like F. A. Freyhan, H. Lehmann, and H.-L. Teuber) from Berlin seemed to integrate easily, in contrast to colleagues of more advanced age. Some of the former chiefs and senior assistants of Berlin’s neurological departments could achieve a successful resettlement (C. E. Benda, E. Haase, C. F. List, and F. Quadfasel) and some a minor degree of success (F. H. Lewy and K. Goldstein). A group of neuropsychiatrists from Bonhoeffer’s staff at the Berlin Charité Hospital could rely on the forceful intercession of their former chief. The impact of the émigré colleagues on North American neuroscience is traced in some cases. Apart from the influential field of psychoanalysis, a more diffuse infiltration of German and European neuropsychiatry may be assumed. The contribution to the postwar blossoming of neuropsychology by the émigré neuroscientists K. Goldstein, F. Quadfasel, and H.-L. Teuber is demonstrated in this article.     

Classic Studies on the Potential of Stem Cell Neuroregeneration

The 1990s and 2000s were the beginning of an exciting time period for developmental neuroscience and neural stem cell research. By better understanding brain plasticity and the birth of new neurons in the adult brain, contrary to established dogma, hope for therapy from devastating neurological diseases was generated. The potential for stem cells to provide functional recovery in humans remains to be further tested and to further move into the clinical trial realm. The future certainly has great promise on stem cells to assist in alleviation of difficult-to-treat neurologic disorders. This article reviews classic studies of the 1990s and 2000s that paved the way for the advances of today, which can in turn lead to tomorrow’s therapies.     

The historical origins of the vegetative state: Received wisdom and the utility of the text

The persistent vegetative state (PVS) is one of the most iconic and misunderstood phrases in clinical neuroscience. Coined as a diagnostic category by Scottish neurosurgeon Bryan Jennett and American neurologist Fred Plum in 1972, the phrase “vegetative” first appeared in Aristotle’s treatise On the Soul (circa mid-fourth century BCE). Aristotle influenced neuroscientists of the nineteenth and early-twentieth centuries, Xavier Bichat and Walter Timme, and informed their conceptions of the vegetative nervous system. Plum credits Bichat and Timme in his use of the phrase, thus putting the ancient and modern in dialogue. In addition to exploring Aristotle’s definition of the “vegetative” in the original Greek, we put Aristotle in conversation with his contemporaries—Plato and the Hippocratics—to better apprehend theories of mind and consciousness in antiquity. Utilizing the discipline of reception studies in classics scholarship, we demonstrate the importance of etymology and historical origin when considering modern medical nosology.     

Highly qualified rural youth: why do young graduates return to their home region?

This paper addresses the motivations underlying migration decision-making in the case of young university graduates returning to their rural home region in Switzerland. Empirical results show the joint role of social ties, living environment, and job opportunities, although the weight given to each of these factors varies between graduates. Some strategies used by the graduates to cope with a limited labour market are furthermore identified. I argue that internal migrations are far from being the sole consequence of labour market conditions and that a greater appreciation of non-economic issues is needed.     

Some Late Ming Western Technical Terms and Their Implications for Cultural Transformation: “Brain,” “Geometry,” “Globe,” and “Cathay”

The cluster of technical terms that the Jesuit Matteo Ricci and his Chinese partners Xu Guangqi and Li Zhizao cotranslated and introduced into Chinese in the late Ming dynasty was of significance for Chinas cultural transformation. For instance, “brain” replaced “heart” as a specific term referring to the organ of consciousness and memory. The classical Chinese interrogative numeral jihe was used to represent the core mathematical term “geometry”. Diqiu, meaning “the globe of the earth” in English, was minted to amend the traditional hemispherical dome cosmology. The identification of “Cathay” with China clarified the ambiguity in the Western geographical concept of the Far East, which had existed since the Middle Ages. Translated from Wuhan University Journal (Humanity Sciences), No. 6, 2003     

安徽淮北相城战国至汉代大型排水设施发掘简报

相城战国至汉代时期大型排水设施位于今安徽省淮北市相山区,2009年3～6月进行基本建设时发现,淮北市博物馆对其进行了抢救性发掘。该遗址面积较大,相关遗迹极具规模,发现的大型排水设施与临淄齐国故城大型排水设施的建筑材料、构筑方法、设计理念有许多共同之处,但又具有自身特点,在我国古代城市建筑遗迹中较为罕见,具有重要意义,为研究战国至汉代相城的历史及中国古代城市发展提供了重要的参考资料。     

Diffusion of Electrical Current in the Experiments of Fritsch and Hitzig and Ferrier Failed to Negate Their Conclusion of the Existence of Cerebral Motor Centers

This paper explores the implications of an early criticism of the stimulation studies of Fritsch and Hitzig and Ferrier for localized brain functions. Fritsch and Hitzig and Ferrier concluded that motor centers reside in the cortices of the hemispheres. Their studies were replicated, but their conclusions were not generally accepted initially. The most salient, laboratory-based criticism was that the electrical current used for stimulation diffused well beyond the cortex making their conclusion of cerebral motor centers unacceptable. The diffusion argument was essentially a French suggestion. Ferrier's and American research and interpretations provided data and arguments against it.     

Pierre Marie: Gifted Intellect,Poor Timing and Unchecked Emotionality

Pierre Marie was a prominent member of the French neurological world of the early twentieth century. Having been trained by the celebrated physician, J-M Charcot, Marie remained influenced by his teacher throughout his career. Because of this influence, his career can be logically divided into three phases: first, the early years under the direct mentorship of Charcot (1878-1893); secondly, the aftermath of Charcot’s death when Marie left his teacher’s institution, the Salpêtrière hospital and established himself at the Bicêtre hospital in southern Paris (1893-1918); and finally, Marie’s return to the Salpêtrière to assume the original Charcot chaired professorship, albeit as an aged man (1918-1925). This essay examines Marie’s career with an emphasis on documentation of the combined attributes of a gifted intellect as well as a heated emotionality. In the context of his time, these elements prompted Marie to enter into controversies and medico-political battles that advanced neurological knowledge, but likely disadvantaged him in his career successes.