Essentials in the use of mycolic acid biomarkers for tuberculosis detection: response to “High-throughput mass spectrometric analysis of 1400-year-old mycolic acids as biomarkers for ancient tuberculosis infection” by

High molecular weight long-chain mycolic acids are key structural components of the cell envelope of Mycobacterium tuberculosis and they are established as biomarkers for the identification of both ancient and modern tuberculosis. Mycolic acids from M. tuberculosis have a characteristic profile, reflecting contributions from five major distinct homologous series of mycolate structural types. Diagnosis of tuberculosis in archaeological material, using mycolic acid biomarkers, depends on objective recognition of the key characteristic mycolic acid components. A recent article in this journal claimed that tuberculosis could be confirmed in ancient bones by high throughput mass spectrometric analysis of mycolic acids. Scrutiny of the data presented reveals no convincing evidence for the presence of mycolic acids, characteristic of the M. tuberculosis complex, in the skeletal remains examined. This communication reviews the essential criteria necessary for positive tuberculosis diagnosis, using mycolic acids.     

Clustering and Dispersion of Duopolists in a Linear Market

The locations that two sellers will choose in a linear market has long been of interest. It is well accepted that firms will tend to cluster in the center of the market as long as demand for the product is inelastic and the market area is bounded. It has also been stated that clustering is less strong as demand becomes more elastic, but questions of when this dispersion occurs and what affects it remain to be addressed. This paper further explores clustering in spatial duopoly as elastic demand is allowed. Results indicate that the clustering behavior of sellers is related to the price of the product they sell, the cost to the consumer of acquiring the product, and the elasticity of demand. Locations of sellers in a linear market will lie between the median location and the quartiles as these parameters vary.     

Some aspects of change in flaked stone industries of the mesolithic and neolithic in Southern Britain

In a recent article, one of the writers suggested that the traditional bipartite division of the British Mesolithic, based on consideration of microlith types, was reflected in the shape of waste flakes (Pitts, 1978a). Four early assemblages were dominated by narrow flakes, in contrast to three later ones with a higher representation of broader flakes. In this paper, the originally tentative conclusions are explored in greater detail, and the next major boundary, the start of the Neolithic, is investigated. Related changes in the tool components are also examined and the outlines of an explanatory framework are proposed.     

American digger and archaeology (Respond to this article at http://www.therai.org.uk/at/debate)

This editorial reflects on the nature of public archaeology. It looks at the relationship archaeologists have with popular TV, focusing in particular on the new series American digger by Spike TV, and Diggers by National Geographic, and reflects on the relationship archaeologists have with amateurs using metal detectors to uncover treasures.     

Globalizing the local in Roman Britain: An anthropological approach to social change

This article considers the incorporation of part of Britain into the Roman empire in the context of globalization theory and world-systems history. Emphasis is placed on the local effects of the expansion of global systems and their impact on the social practices of eating and drinking at a range of settlements in the southeast of Britain in the Iron Age to Roman transition, c. 50 BC–AD 200. Through the analysis of consumption practices via quantitative pottery assemblage data, it is argued that globalization offers a more sophisticated framework to describe change than current archaeological approaches to Romanization and identity. The results show that while much of the populace was subject to a progressively homogenizing supply of food-related pottery vessels, the use of such technologies was negotiated within social practices drawing on the integration of both local and global cultural elements. Such findings highlight the potential of critical applications of globalization theory to conceptualize economic, social, and cultural changes in Roman provincial societies.