Classic Studies on the Potential of Stem Cell Neuroregeneration

The 1990s and 2000s were the beginning of an exciting time period for developmental neuroscience and neural stem cell research. By better understanding brain plasticity and the birth of new neurons in the adult brain, contrary to established dogma, hope for therapy from devastating neurological diseases was generated. The potential for stem cells to provide functional recovery in humans remains to be further tested and to further move into the clinical trial realm. The future certainly has great promise on stem cells to assist in alleviation of difficult-to-treat neurologic disorders. This article reviews classic studies of the 1990s and 2000s that paved the way for the advances of today, which can in turn lead to tomorrow’s therapies.     

‘Culture’, ‘sustainable development’ and cultural policy: a contrarian view

Abstract

This essay offers a critical analysis of the ‘culture and sustainable development’ discourse, notably among cultural activists and in actually existing cultural policy. It interrogates the utility of the narrative, seeks to uncover the semantic manoeuvres it employs and challenges the conventional wisdom it represents. The essay first explores the itinerary of the ductile notion of ‘sustainability’, the ways in which it has been stretched far beyond the original intent of those who coined the term, and identifies the conceptual discontents that this semantic multiplication has entailed. It hypothesizes that precisely because the term ‘sustainable’ and its derivatives are so acceptable and malleable at the same time, they have been easy to yoke to the bandwagon of the many-faceted and totalizing process that is ‘development’, allowing many different actors to project their interests, hopes, and aspirations under this composite banner. The essay then analyses the campaign to make culture ‘the fourth pillar of sustainability’ under the banner of the movement called ‘Agenda 21 for Culture’. It concludes with a plea for a return to the original ecological focus of the term ‘sustainability’ – notably as regards climate change – and outlines some cultural policy responses such a focus can and should generate.     

Conceptualizing Urban Inequalities as a Complex Socio-Technical Phenomenon

The United Nations World Social Report (2020) reveals that more than two thirds of the world's population live in countries where urban inequalities have increased in the last three decades. While urban inequalities are traditionally characterized as an economic issue, scholars are increasingly applying methods from geospatial analysis to study them. In the context of these advancements, it remains unclear what underlying perspectives are guiding decisions to concentrate on certain aspects of urban inequalities, while potentially ignoring others. We address this gap by reviewing the literature centered on the geospatial analysis of urban inequalities and identify three predominant research lenses from accessibility, distribution, and policy and stakeholder perspectives. As a primary contribution of this article, we connect the perspectives with ideas drawn from complexity theory to develop an overarching socio-technical framework for how urban inequalities emerge over space and time. While traditional scientific frameworks seek to increase knowledge through causality, complexity science acknowledges the inherent challenges in defining, understanding and solving complex problems such as urban inequalities, which has profound implications for their representation, modeling and interpretation. We critically reflect on the framework through key relational themes and insights drawn from the literature and close with considerations for future research.     

Applications of satellite remote sensing for research and heritage management in Indian prehistory

Multidisciplinary spatial studies are relatively limited in Indian archaeology, despite their potential for research and heritage management. This paper discusses applications of satellite remote sensing, field studies and GIS, in the context of Palaeolithic archaeology. The study region covers an area of around 8000 km², in the state of Tamil Nadu, South India, and is characterized by a rich and diverse Palaeolithic record. Satellite images of varied spatial resolutions were interpreted to address both regional and site-specific research questions. Thematic maps were generated from satellite data and refined with intensive field investigations. These were used for demarcating sources of raw material, and in investigating variability in the distribution of sites through time in relation to a range of geological and geomorphological features. Satellite data and field studies also aided in mapping impacts on sites resulting from modern landuse patterns. The paper also discusses the development and testing of a model to detect potential areas where new sites may be rapidly located.     

Cultural diplomacy: India does it differently

Abstract

This article reviews the singularities of Indian doctrine and practice of cultural diplomacy, beginning with the observation that this term and the notions of ‘soft power’ and ‘public diplomacy’ commonly associated with cultural diplomacy elsewhere do not have much purchase in India, where the spirit and letter of ‘international cultural relations’ are the preferred currency. The essay explores the historical grounding for this preference, as well as the attitudes and practice that flow from it. Another singularity is the role and importance of the Indian diaspora: overseas populations of Indian origin have been both a significant segment of the target audience for international cultural relations – as if a certain idea of India had to be projected abroad to a part of itself – and a significant ‘co-producer’ in projecting that image. A third is the emergence of a new avatar of the diasporic Indian, now identified with capitalist entrepreneurship.     

New Challenges in Land Use in Nepal: Reflections on the Booming Real-estate Sector in Chitwan and Kathmandu Valley

Domestic commercial land acquisition is a recent phenomenon in Nepal; it is rapidly expanding and increasingly occupying productive agricultural land for real estate and other non-agricultural commercial purposes. This paper analyses the present situation and the implications of domestic land acquisition, and identifies actors and forms of land deals and associated conflicts. The study was conducted in Kathmandu Valley (27° 32′ 13″ N to 27° 49′ 10″ N and 85° 11′ 31″ E to 85° 31′ 38″ E) and Chitwan District (83°54′ 45″ to 84°48′15″ E and 27°21′45″ to 27°52′ 30″ N), the areas of Nepal most affected by domestic land acquisition. In the absence of statistical material, purposive sampling was used to identify households for a survey of 208 respondents; this was complemented by qualitative research and a review of media and other documents. Respondents confirmed that land acquisition is increasing at a very rapid rate and is driven by a nexus of politicians, land brokers and real-estate actors, and that it has caused not only food insecurity but also numerous conflicts between local people and the land deal actors. Existing policies and legislations were found to be inadequate to address the challenges brought about by the domestic land acquisition process in Nepal.     

The Effects of Localization on Economic Performance: Analysis of Spanish Tourism Clusters

The sun, sea and sand model that has characterized the Spanish tourism sector and has caused Spain's tourist sector to become a world-class industry is actually undergoing drastic changes. This model is based on the existence of major tourism destinations characterized by high levels of industry specialisation, which makes them a target of analysis as tourism clusters in which the geographic concentration of synergies reinforces the competitive position. In this study, Spanish tourism clusters are identified using quantitative methods and the current validity of the economies of location that have made them possible are also analysed. Although all the identified clusters can be defined as mature and became less significant during the last decade in Spanish tourism, according to the results the creation of externalities measured in terms of higher generation of profit is higher in companies belonging to the tourism clusters than in those outside of them.