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The treatment of childhood leukaemia is seen as a successfulhistorical example of the operation of the randomized controlledtrial and continues to inform contemporary policy making onsuch trials within health research. This article analyses thescientists story of success through historicalresearch. It tells us about the organizational and professionalstructures of such research post-war in the United Kingdom,and examines the history of the cancer clinical trial throughthis particular example. The story reveals a more complex picturethan the heroic one, with key developments inthe operation of post-war science, both in terms of its infrastructureand of its scientific networks, not least the rise of co-operativeworking among clinicians and the growing importance of statisticiansin medical research and practice. It also underlines differencesbetween the British and US approaches in which the role of onehealth system, the National Health Service, helped structuredifferent, initially less intensive, patterns of response. 相似文献
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