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In the contemporary knowledge economy, characterized by both globalization and localization of economic activities, the ability of both firms and their respective regions to adapt to changes in their external environment and to retain their competitiveness is closely related to their capacity to innovate and to continually upgrade existing structures, practices and knowledge bases. In this respect, co-location of firms operating in the new knowledge-intensive sectors is typically considered to be beneficial for both the firms themselves and for their respective regional economies. In this study, we considered whether knowledge-based industrial renewal is possible in peripheral regions. The empirical study was designed to identify tendencies towards and potential concentrations of new knowledge-intensive industries in the relatively peripheral region of Pohjois-Savo in Finland. The strength of such tendencies was determined by employing the Herfindahl index and location-quotient methods. The analysis indicates that while the more traditional industries still appear to be dominating the region's economic landscape, the new knowledge-intensive industries have gained at least a foothold in the region, indicating a potential target for local policymakers' further development efforts. Pohjois-Savo can be considered to be a typical Finnish region, characterized by a large central city with a university, a few smaller sub-regional centres and the surrounding large rural periphery. However, earlier literature with the same focus is lacking and regional strategies and entrepreneurial structures differ in different regions; thus, we cannot establish whether these conclusions hold in other regions in Finland or how applicable these results are in an international context.  相似文献   
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The aim of this study is to look at upper body functional modifications caused by mechanical loading. We look at 4th lumbar vertebra as well as fibrous humeral musculoskeletal stress markers (MSMs). This study uses information provided by magnetic resonance images of living individuals from the University of Oulu Hospital data banks (N = 91), archaeological skeletons from Sweden (N = 54) and England (N = 61), and autopsied skeletal collection of early 20th century Finns in Natural History Museum, University of Helsinki (N = 48). The lumbar vertebrae and MSM are subjected to mechanical loading caused by the upper body weight and loads lifted and/or carried. We hypothesized that the vertebral size reflect body size, habitual mechanical loading and the overall skeletal robusticity as mechanical competence to withstand mechanical loading standardized to body size, which has decreased over millennia. For Helsinki material occupation, age and sex is known and the material was used in Niinimäki (2011). In the study by Niinimäki (2011) MSM were found to be affected by the intensity of muscular action as well as body size and age. This study is reviewed here in light of re-analysis of the data to follow the current anatomical understanding of the entheses as well as viewing MSMs as a part of upper body functional complex. Only fibrous entheses were included in the re-analysis. Furthermore, due to small number of females where activity intensity could be assessed, females were dropped from the re-analysis.  相似文献   
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As it has now been widely argued, innovation is ever more seldom the product of isolated firms but usually requires a combination of multiple technologies, skills and competences, part of which have to be acquired from outside the boundaries of the innovating firm. As the literature on regional systems of innovation and other territorial innovation models suggests, the region is the most appropriate spatial level for investigating and understanding the nature of firms’ external knowledge acquisition in their innovation processes, as well as for identifying the critical actors and factors contributing to them. Unlike the majority of studies focusing on the innovation activities of firms at the regional level, this paper focuses not on the actual importance of different location factors, but on the perceptions of small- and medium-sized firms entrepreneurs of the quality of different factors in their regional innovation environment. By identifying differences between the perceptions of innovative and less-innovative firms, this study contributes to the literature on innovation as a regional-level phenomenon, and also tentatively puts forward some managerial and policy implications, as well as suggestions for further research.  相似文献   
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