Seventeenth‐ and eighteenth‐century commentators on the chemical composition of the brain

Abstract

The period between 1600 and 1800 was one of great change in the history of science, generally, and in the history of chemistry, specifically. It opened with Francis Bacon's visionary recognition of the benefits to mankind that would accrue from the expansion of scientia and closed with the overthrow of the phlogiston hypothesis. New chemical knowledge resulted from the efforts of the alchemists, especially the Paracelsians, and of the phlogistic philosophers, some of it recorded by writers of magic books (Thorndike, 1958; Camporesi, 1989). The authors of these works reflected ‘the general mentality… imbued with magic, occult beliefs, unreal suggestions, ‘voices’, and ‘rumours’, … ‘errors’ and ‘prejudices’.‘ In respect to brain chemistry there appeared, beside the fantastic, elements of fact that characterise this period as embracing the ‘pre‐history’ of neurochemistry.     

One Hundred Members of the Association of British Neurologists: A Collective Biography for 1933–1960

This article draws a quantitative portrait of British neurology in the interwar and postwar periods through an analysis of the first 100 members of the Association of British Neurologists. Through its presentation of data, this article argues that the members of the Association of British Neurologists were extremely ambitious and as a whole had attained unusually high levels of social, professional, and civil distinction. It makes this argument through an examination of their social and educational backgrounds, the trajectory of their careers, and their achievements in the form of editorships of journals, professorships in medicine, positions in government, honorary degrees, and other indicators of merit. This collective study therefore offers an explanation for how the Association of British Neurologists transformed from an elite club in the 1930s into an organization that eventually came to represent clinical neurology across Britain.     

Last meals inferred from the possible gut contents of a mummy: A case study from Astana Cemetery,Xinjiang, China*

The gut contents of ancient humans have been proven to be the most direct evidence for palaeodietary study. In the Xinjiang region of north-west China, large numbers of mummies are well preserved owing to the extremely dry environment to be found there. Fourier-transform infrared spectroscopy (FTIR) combined with multi-archaeobotanical methods, including macrofossil examination, starch grain analysis, phytolith analysis and bran fragments analysis, were applied to investigate the possible gut contents (c.1300 bp by ¹⁴C dating) of a person unearthed at tomb 75TAM601 in Astana Cemetery, which were the public graveyards of the ancient Gaochang people (residents of Turpan, dating from about the third to the ninth centuries ce ), in Turpan, Xinjiang. The result of the FTIR analysis showed that the matrix of the possible gut contents consisted of protein and starch and was characterized as undigested food residue. The white mineral fragments of this sample were from the decomposition products of the skeleton. The microfossil analysis demonstrated that Setaria italica, Panicum miliaceum and Triticum aestivum were the main cereal resources for the last meals eaten by the deceased. Moreover, direct macrofossil evidence also advocates for the importance of the three aforementioned cereal crops and fruits of Cucumis melo and Vitis vinifera in the person's diet.     

Citizen and government co-production of data: Analyzing the challenges to government adoption of VGI

With the recent rise of open government and open data initiatives, governments are increasingly adopting new approaches of citizen participation to support a more democratic, transparent, and inclusive government system. Among other forms of citizen participation, Volunteered Geographic Information (VGI) is one approach to connecting citizens and government. Accepting VGI as a way to update government data or collect near-real-time information from citizens can create a partner-like relationship where citizens voluntarily contribute time and effort to support government actions. However, as a relatively new approach to citizen participation and data collection, VGI requires evaluation from the perspective of governments. This research investigates the challenges and opportunities that governments have found through the implementation of VGI projects. Results are drawn from interviews conducted with 19 government organizations, revealing organizational and technical challenges that limit the adoption of VGI. Organizational challenges are associated with government mindset, implementation, and project management, while technical challenges involve development of the system and quality of data. Given these challenges, we derive recommendations within the phases of project initiation, implementation, and expansion that can foster VGI adoption in government.     

The Art of Geographical Analysis

Professor Arthur Getis was a prominent geographical analysis researcher and proponent. His research in geographical analysis was broad, with an eye on theoretical developments and application-oriented details. However, there was so much more. His active participation and engaged discussion at symposia and conferences, in sessions, during breaks and less formally over drinks or a meal, stand out, even postretirement. His service and mentoring in many forms too were invaluable. In what follows, an overview of his career and contributions are provided. Additionally, observations and broader significance are offered as a set of rules to live by based on my three decades of interaction with Professor Getis.     

A Potential Case of Social Bankruptcy: States' AFDC Payments and Their Teen Birth Rates

Based on a pooled time series analysis that covers a 30-year period at five different time points—1960, 1970, 1980, 1985, and 1990—this research examines the relationship between states' Aid to Families with Dependent Children (AFDC) payments and teen birth rates. Drawing on rational choice theories, we expected the effects of states' AFDC payments on their teen birth rates to be positive, taking into account states' divorce rates, population change rates, unemployment rates, racial composition, and poverty rates. The effects of states'AFDC payments were significant in a negative direction in Model 1, a random effects model; they also were significant in a negative direction in Model 2 when we controlled for the effects of year; however, when we controlled for the effects of year and state in Model 3, they were not significant. The findings do not support assumptions regarding the incentive effects of welfare that underlie rational choice theories in states where teen birth rates are higher. If anything, teen birth rates are higher in states where AFDC payments are lower. Implications for policy and further research are discussed in relation to the positive effects of states' poverty and population change rates on the state teen birth rate problem.