The Growth Cone as Seen Through Cajal's Original Histological Preparations and Publications

Abstract

Multiple sclerosis (MS) was first presented in a clinical setting in 1838. In this paper the presentation and treatment of a transient hemiparesis in a drummer in 1789 is discussed. This may have been an early case of MS and presents evidence against the theory that MS is an infectious disease beginning in the 19th century.     

Historical Development of the Dopamine Hypothesis of Schizophrenia

This review examines the history of discoveries that contributed to development of the dopamine hypothesis of schizophrenia. The origin of the hypothesis is traced to the recognition that neuroleptic drugs interfere with brain dopamine function. This insight was derived from two distinct lines of research. The first line originated from the discovery in 1956 that reserpine depletes brain serotonin. This finding resulted in a sequence of studies that led to the discovery that brain dopamine is involved in neuroleptic-induced extrapyramidal motor disturbances. The second line of research was aimed at determining the mechanism of action of psychomotor stimulants. This research produced evidence that stimulants directly or indirectly activate brain dopamine receptors. Because nonreserpine neuroleptics such as chlorpromazine block stimulant-induced movement, these findings suggested that neuroleptics were dopamine antagonists. Most previous accounts of the development of the dopamine hypothesis of schizophrenia emphasize the first line of research and ignore the second.     

The British Archaeological Association Honorary Secretary’s Report For 1939

Abstract

In the Lady chapel at the east end of the north aisle of the church at Pucklechurch (Gloucestershire) are two effigial monuments, which have received little scholarly attention. The monuments are attributed to William de Cheltenham (d. between 1371 and 1374) and his wife Eleanor, and were set up in his lifetime within the chantry chapel dedicated to St Mary which William received licence to establish at Pucklechurch in 1337. Little remains of the chapel except an exquisite altar frontal. During the 19th century the two effigies were transposed. Various aspects of the conception and design of the Pucklechurch monuments reflect developments in monumental sculpture in Herefordshire.     

Death in the sun: the bioarchaeology of an early post-medieval hospital in Gibraltar

SUMMARY: In 2014, during construction work at the ex-Civil Hospital in Gibraltar, excavations led by the Gibraltar Museum revealed a major, previously unknown burial ground containing more than 200 skeletons. We present the historical, archaeological and radiometric dating evidence from the site alongside the results of initial osteological analyses. The data indicate that the burials pertain to an earlier 16th-century Spanish hospice, and therefore stand to offer new insights into the functioning of this early modern hospital and the health and movements of people at a time of incipient globalization.     

A Multi-Method Approach to Reconstructing Occupational History and Activity Areas: A Case Study at the Formative Site of Tlalancaleca,Central Mexico

While surface collection constitutes an important component of field research at the site and regional levels, the association between surface and sub-surface materials needs to be examined through independent lines of evidence. This study employed manual bucket auger probing and soil geochemistry at the Formative site of Tlalancaleca, Central Mexico (800 b.c.–a.d. 250), to evaluate the results of surface collection and to understand the formation process of the anthropogenic landscape. The combined results at one of the largest architectural complexes at Tlalancaleca indicate that it was built during the Late Formative period (500–100 b.c.) and rebuilt during the subsequent Terminal Formative period (100 b.c.–a.d. 250), which is corroborated by radiocarbon dates. Moreover, the results suggest segregated uses of space such as cooking/storage, waste disposal, and craft production areas within the complex. Overall results demonstrate the effectiveness of this multi-method approach for reconstructing occupational history and activity areas.     

Religion,society, and culture

Morris, Brian. Anthropological Studies of Religion: An Introductory Text. Cambridge: Cambridge University Press, 1987. ix + 369 pp. including chapter notes and references, selected bibliography, and index. $42.50 cloth, $12.95 paper.

Webster, Graham. Celtic Religion in Roman Britain. Totowa: Barnes & Noble, 1987. 205 pp. including chapter notes and references, photographs and illustrations, abbreviations, classical sources, selected bibliography, and index. $30.00 cloth.

Weller, Robert P. Unities and Diversities in Chinese Religion. Seattle: University of Washington Press, 1987. viii + 215 pp. including appendices, notes, references, and index. $22.50 cloth.     

Beyond cultural relativism

Ronald P. Rohner. They Love Me, They Love Me Not: A Worldwide Study of the Effects of Parental Acceptance and Rejection. New Haven, Conn.: H.R.A.F. Press, 1975. 300 pp. Figures, tables, appendices, bibliography, and index. $12.00 (cloth), $6.00 (paper).