The Struggle to Breathe: Living at Life Expectancy with Cystic Fibrosis

The first sizeable cohort of people living with cystic fibrosis(CF) has now reached adulthood. Gradual improvements in thediagnosis and treatment of the disease have increased life expectancyto approximately 32 years. Members of this cohort have livedall their lives near, at, or slightly beyond life expectancy.The authors tell the story of Lori Morris-Hughes, a 36-yearold who balances the demands of work and family life with life-longterminal illness. Whereas many accounts of medical advancementwrite the lived experiences of the ill out of history, Morris-Hughes'sillness narrative provides an account of the ways in which thetemporal and social conditions of existence are problematicfor those who live during times of increased life expectancy.Oral history is a particularly appropriate method of researchin the field of illness narrative.     

Tuberculosis among Iron Age individuals from Tyva,South Siberia: palaeopathological and biomolecular findings

The study focuses on the evidence for tuberculosis apparent in an Iron Age population recovered from the cemetery of Aymyrlyg, Tyva (Tuva), South Siberia. A recent wholly molecular study of five of the cases confirmed the presence of Mycobacterium tuberculosis (MTB) complex DNA in four of the individuals. In all cases the disease was caused by strains of Mycobacterium bovis rather than Mycobacterium tuberculosis and represents the first positive identification of the bovine form of the disease in archaeological human remains. Details of the palaeopathological characteristics of the cases are provided in the current paper, while the molecular observations are extended to include a quantitative evaluation of the surviving mycobacterial DNA using real-time PCR. The observation that bovine tuberculosis was the pathogen responsible is discussed in terms of current understanding of the evolution of the MTB complex as well as the implications for future ancient DNA studies in this area.     

The politics of rebirth in Colm Tóibín's ‘Three Friends’ and ‘A Long Winter’

This paper explores the compatibility of Catholic and homosexual identities. Because the language of Catholicism is so deeply entrenched in the popular imagination, I aim to show that not only does it provide a vocabulary for oppression but also for change. For the contemporary Irish novelist, the latter means conferring new meaning onto formerly oppressive language. In ‘Three Friends’ and ‘A Long Winter’, two short stories from Tóibín's Mothers and Sons (2007), the protagonists undergo a ‘baptism’ that signals their emergence into a new world, one tolerant of homosexual desire. Fergus, in the ocean, and Miquel, in the bathtub, experience moments at once erotic and cleansing. I outline their participation in the traditional world – the time before their bathing rites – in contradistinction to a re-imagined, modern, ‘queer’ world. I argue that Tóibín appropriates a Catholic, and therefore heteronormative, rite in a way that includes homosexuals. Thus, he reworks an oppressive framework in order to allow for the formerly excluded to participate and celebrate their non-heteronormativity, or queerness.     

Henri Kowalski (1841–1916): A French Musician in Colonial Australia

French virtuoso pianist and composer Henri Kowalski visited Australia in 1880 and then returned in 1885 when he settled in Sydney for twelve years. This article explores his introduction of French repertoire, institutional practices and musical instruments to colonial Sydney. It demonstrates that for a short period at the end of the nineteenth century, there was a much stronger French presence in musical life in Australia than has previously been acknowledged.     

Biostratigraphic Evidence Relating to the Age‐Old Question of Hannibal's Invasion of Italy,II: Chemical Biomarkers and Microbial Signatures

As discussed in Part I, a large accumulation of mammalian faeces at the mire site in the upper Guil Valley near Mt. Viso, dated to 2168 cal ¹⁴C yr., provides the first evidence of the passage of substantial but indeterminate numbers of mammals within the time frame of the Punic invasion of Italia. Specialized organic biomarkers bound up in a highly convoluted and bioturbated bed constitute an unusual anomaly in a histosol comprised of fibric and hemist horizons that are usually expected to display horizontal bedding. The presence of deoxycholic acid and ethylcoprostanol derived from faecal matter, coupled with high relative numbers of Clostridia 16S rRNA genes, suggests a substantial accumulation of mammalian faeces at the site over 2000 years ago. The results reported here constitute the first chemical and biological evidence of the passage of large numbers of mammals, possibly indicating the route of the Hannibalic army at this time. Combined with the geological analysis reported in Part I, these data provide a background supporting the need for further historical archaeological exploration in this area.     

Possible neurofibromatosis in a Scythian period individual from the cemetery of Aymyrlyg,Tuva, South Siberia

The article presents evidence of possible neurofibromatosis in a female cranium discovered in a Scythian period (7th–2nd century BC ) context from the cemetery complex of Aymyrlyg, Tuva, south Siberia. The diagnosis of neurofibromatosis has been suggested on the basis of enlarged orbits, signs for the presence of a soft tissue tumour in the left orbit, facial abnormalities and the survival age of the individual. Neurofibromatosis is a congenital condition which, to the best of the authors' knowledge, has previously been described in only one other instance in the palaeopathological literature. Differential diagnoses includes angiomata, dermoid cysts and developmental glaucoma. © 1998 John Wiley & Sons, Ltd.