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For five decades it has been generally accepted that reserpine, an antihypertensive and antipsychotic drug, causes depression. The discovery that reserpine depletes brain monoamines was an important factor in the development of the monoamine hypothesis of depression, and it continues to be widely cited in support of this hypothesis. The present paper argues that, contrary to prevailing belief, reserpine is not depressogenic. The reason for perpetuation of this myth is reluctance to discard the monoamine hypothesis. This hypothesis ushered the modern biochemical paradigm into psychiatry and is still of great importance. It serves as a heuristic to guide research, it enhances psychiatry’s prestige, and it helps to validate and promote drug therapy for depression and other mental disorders.  相似文献   
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Since being excavated in 2003, the skull of LB1 (the holotype of Homo floresiensis) has been given many faces, though the details regarding how each was accomplished are typically few. Here we detail our application of known, and verified, relationships between the skull and soft tissues of anatomically modern humans to produce an evidence-based facial approximation of LB1. We then compare our results to nine pre-existing LB1 faces using geometric morphometrics. These analyses suggest our facial approximation differs in proportional facial width, upper lip height and nasal morphology. Some of these differences are likely due to a different interpretation of taphonomic and excavation damage, application of different 'forensic' methods and/or an idiosyncratic incorporation of aspects of non-human primate morphology. Other differences, and in particular upper lip height, are less justifiable in relation to the skeletal evidence.  相似文献   
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This paper presents 19 AMS radiocarbon dates from nine pre-Hispanic Caribbean (Taíno/Lucayan) wooden sculptures in the British Museum collections, provenanced to Jamaica, Hispaniola and the Bahamas. Together with strontium isotope results and wood and resin identifications, these data build a material and chronological context for some of the most recognised examples of Taíno art – from duhos (ceremonial seats) and cemís (free standing depictions of deities, ancestors and spirits) to canopied stands used to hold hallucinogenic drugs during the cohoba ceremony. Each sculpture widens our understanding of Caribbean carving traditions, stylistic variation, chronologies and material resource utilisation. A group of three sculptures recovered from Carpenters Mountains, Jamaica, carved by AD 1300 and brought together as a ceremonial ‘set’, each appear to have had their inlays renewed over a century later, suggesting long-term use. Three key examples of the main Caribbean duho categories (high-back, low-back and extended), provide insights into the diversity of styles present in the region post-AD 1100. The British Museum's corpus enables an exploration of regional styles, and potentially the work of individual artists.  相似文献   
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Abstract. This paper examines the relationship between nationalist movements and minority languages, with particular emphasis on examples from Britain and Ireland. This relationship is less straightforward than often assumed, and the media's role in it is particularly complex. The varying political uses of minority language broadcasting are discussed, along with the implications of the separation between cultural and political nationalism. The notion of the routine banality of daily broadcasting is used to indicate how such broadcasting can work against nationalist mobilisation. Finally, Ireland is examined in the light of the previous discussion in order to offer an explanation of why it was so far behind many other areas in the provision of minority language broadcasting.  相似文献   
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