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71.
We report here the first results of a method to extract and sequence mature enamel proteins from modern human and Neanderthal tooth enamel. Using MALDI-TOF/TOF mass spectrometry and a combination of direct sequencing and peptide mass mapping we have sequenced a peptide from the tyrosine-rich amelogenin peptide (TRAP) of the X isoform of the amelogenin protein for modern and recent human samples. We also report our results from two Neanderthal enamel samples where we were also able to recover fragments of the TRAP protein, which had a similar sequence to the modern human samples.  相似文献   
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In the 1970s, the discoveries of Palaeolithic human remains in the caves of Dar es Soltane 2, El Harhoura 1 and Les Contrebandiers reinforced interest in the sites of the Témara region. These sites, often cited, have been the object of numerous investigations which have produced a major contribution to the prehistory of Morocco. Over the past 15 years, research at two key sites, El Mnasra and El Harhoura 2, have considerably enhanced the available data for this region. Preliminary results obtained from excavations since 2001, allow us to present the palaeoenvironmental framework and describe the technological behaviour of prehistoric groups within a re-evaluated stratigraphic context. The microfaunal and macrofaunal assemblages are analysed according to systematics, taphonomy and palaeoecology. The lithic and bone industries document patterns of raw material acquisition and transformation. Within the context of the history of more than 60 years of research in the region of Témara, this contribution allows us to approach the question of Palaeolithic population on the basis of recent, and for the most part new, data and evidence.  相似文献   
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The Port‐Vendres 4 shipwreck is evidence of coastal export trade between Hispania Citerior and Narbonne in 40/30 BC. The cargo is made up of a particular assemblage of Roman wine amphoras (Pascual 1, Dressel 1B and Lamboglia 2) destined for Gallic markets. Archaeological and archaeometric analyses conducted on a selection of the amphoras allowed the provenance of the cargo to be identified as Hispania Citerior and the central‐southern Tyrrhenian coast of Italy. Iluro and/or Baetulo are proposed as the ports of departure, enabling the reconstruction of the trade route and the historical and economic significance of this shipwreck.  相似文献   
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This paper is a survey of Father Mersenne's views about the classification of sciences, its reasons and its practical consequences. Some emphasis is put on the interconnection between Mersenne's two major ideas about the practice of science: scientific research is an activity mostly devoted to religious apology and to the edification of the people. This religious concern allows him to resist two of the most influential philosophical streams of his time, scepticism and alchemy, which provide some of the major opposition to his works. We also show how an analogical kinship based on theological considerations and on the classification of sciences leads to the same kind of arguments shaping his views about arithmetic, language, and music. Finally, we focus on the connection between Mersenne's theses, especially about the nature and virtue of language and sound, and a more general discussion of the scientific status of music and language in the context of the blooming of academies.  相似文献   
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When it comes to making planning and development decisions, the concepts of small, medium-sized, or large cities are sometimes used to adapt public policies and instruments, or even to highlight challenges that are specific to certain categories of city. In this article, we take a look at the various dimensions that can be used to characterize cities, so as to empirically test a multi-criteria approach and build a typology of Quebec cities. Using an ascending hierarchical classification, we derive 11 classes of cities, whose conceptualization and graphic representation enable us to highlight their role and, in part, to localize their polarized area. This article complements and adds to works undertaken by other researchers over the last 20 years. Although it does not aim to propose specific changes to public policies and instruments, this article may serve to inform public decision makers in the development of such policies and instruments, and to enrich academic debates on the nature of small and medium-sized towns in particular.  相似文献   
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The site of Combe-Grenal is arguably the reference site for the Mousterian of southwest France. Bordes excavated the site over a period of 13 years and generated a large collection of lithics and fauna from a deep series of 64 Lower and Middle Paleolithic levels. Though Bordes only partially published his work at the site, its long stratigraphic sequence and particularly its collections have been subjected to numerous studies over the years and have figured prominently in several long-running debates concerning the Mousterian. Recently, the authors undertook a project to inventory and analyzed these collections along with the documentation of their archaeological context. In so doing, however, a number of serious problems became apparent with the collection in its current state, problems that cannot easily be resolved given the state of the available documentation. These problems have important implications not only for results of studies based on these collections, but more generally, they also point to problems in terms of how archaeological collections are curated.  相似文献   
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