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When “antipsychotic” drugs were introduced into psychiatry in the 1950s, they were thought to work by inducing a state of neurological suppression, which reduced behavioral disturbance as well as psychotic symptoms. This view was reflected in the name “neuroleptic.” Within a few years, however, the idea that the drugs were a disease-specific treatment for schizophrenia or psychosis, and that they worked by modifying the underlying pathology of the condition, replaced this earlier view, and they became known as “antipsychotics.” This transformation of views about the drugs' mode of action occurred with little debate or empirical evaluation in the psychiatric literature and obscured earlier evidence about the nature of these drugs. Drug advertisements in the British Journal of Psychiatry reflect the same changes, although the nondisease-specific view persisted for longer. It is suggested that professional interests rather than scientific merit facilitated the rise of the disease-specific view of drug action. The increasing popularity of atypical antipsychotics makes it important to examine the origins of the assumptions on which modern drug treatment is based.  相似文献   
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SURVEY of a field, immediately north of the early Norman motte-and-bailey castle of Hen Domen, Montgomery, revealed ridge-and-furrow, averaging 4 m. in width, cut by the outer ditch of the bailey. Excavation demonstrated that the ridge-and-furrow extended under the inner rampart of the bailey. Pollen analysis of the buried soil showed the former presence of cereals and the weeds of cultivation. A Carbon-14 date from charcoal in the buried soil reinforced the view that this field-system was in use before the Norman conquest.  相似文献   
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This paper presents 19 AMS radiocarbon dates from nine pre-Hispanic Caribbean (Taíno/Lucayan) wooden sculptures in the British Museum collections, provenanced to Jamaica, Hispaniola and the Bahamas. Together with strontium isotope results and wood and resin identifications, these data build a material and chronological context for some of the most recognised examples of Taíno art – from duhos (ceremonial seats) and cemís (free standing depictions of deities, ancestors and spirits) to canopied stands used to hold hallucinogenic drugs during the cohoba ceremony. Each sculpture widens our understanding of Caribbean carving traditions, stylistic variation, chronologies and material resource utilisation. A group of three sculptures recovered from Carpenters Mountains, Jamaica, carved by AD 1300 and brought together as a ceremonial ‘set’, each appear to have had their inlays renewed over a century later, suggesting long-term use. Three key examples of the main Caribbean duho categories (high-back, low-back and extended), provide insights into the diversity of styles present in the region post-AD 1100. The British Museum's corpus enables an exploration of regional styles, and potentially the work of individual artists.  相似文献   
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Anthropologists have come to realize that even the most ‘traditional’ Melanesian practices and ideologies may be historically shaped by the people's experiences within encompassing regional systems. This article examines the reshaping of local understandings of the village among the Maisin people of Oro Province over the past century. I distinguish three contexts within which Maisin notions of the village have been formed: colonial models of village government imposed before the Second World War; Christian village cooperatives in the post-war colonial period; and village meetings in the 1980s. The paper shows that the idea of the village has a complex evolution, shaped within overlapping dialogues between villagers and significant outsiders and between elder and younger village leaders who have had differing experiences of the outside world and the place of their own community within it.  相似文献   
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