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71.
Historical Archaeology - Catholic missionaries were active among rural populations in Manchuria, in northeast China, around the turn of the 20th century. Their presence influenced everything from...  相似文献   
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This review examines the history of discoveries that contributed to development of the dopamine hypothesis of schizophrenia. The origin of the hypothesis is traced to the recognition that neuroleptic drugs interfere with brain dopamine function. This insight was derived from two distinct lines of research. The first line originated from the discovery in 1956 that reserpine depletes brain serotonin. This finding resulted in a sequence of studies that led to the discovery that brain dopamine is involved in neuroleptic-induced extrapyramidal motor disturbances. The second line of research was aimed at determining the mechanism of action of psychomotor stimulants. This research produced evidence that stimulants directly or indirectly activate brain dopamine receptors. Because nonreserpine neuroleptics such as chlorpromazine block stimulant-induced movement, these findings suggested that neuroleptics were dopamine antagonists. Most previous accounts of the development of the dopamine hypothesis of schizophrenia emphasize the first line of research and ignore the second.  相似文献   
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Abstract

It is increasingly recognised that religion was the mainspring of pre-Reformation domestic ritual in royal as well as episcopal and archiepiscopal households. This article sets out to examine the architectural consequences of this. It argues that from the mid-15th century a small group of high-status residential buildings was planned around the need for lavish liturgical display, particularly the introduction of a cloister. The patrons of such buildings were churchmen of the highest rank such as Henry Beaufort and Thomas Wolsey who, it is argued, had special requirements for their principal residences. These requirements subsequently went on to influence the plans of early Tudor royal palaces, culminating in the reconstruction of Whitehall Palace by Henry VIII in the 1540s.  相似文献   
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SUMMARY: In 2014, during construction work at the ex-Civil Hospital in Gibraltar, excavations led by the Gibraltar Museum revealed a major, previously unknown burial ground containing more than 200 skeletons. We present the historical, archaeological and radiometric dating evidence from the site alongside the results of initial osteological analyses. The data indicate that the burials pertain to an earlier 16th-century Spanish hospice, and therefore stand to offer new insights into the functioning of this early modern hospital and the health and movements of people at a time of incipient globalization.  相似文献   
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In fin-de-siècle Japan, the ideal of "eugenic modernity," or the application of scientific concepts and methods as a means to constitute both the nation and its constituent subjects (New Japanese), crystallized in the space of imperialism. Three of the main themes explored are the application of eugenic principles to make connections between biology, kinship, and the plasticity of the human body; to contemporize historical stigmas; and to promote "pure-bloodedness" and "ethnic-national endogamy" as cultural ideals.  相似文献   
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