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Gunnar Hörnsten 《Journal of the history of the neurosciences》2013,22(1):61-65
Abstract The aim of this study is to find out whether bromide was able to cause conversion of epilepsy to psychosis i.e., so‐called paradoxical normalization such as has been seen in treatment with modern antiepileptic drugs. Spontaneous conversion has been known for three hundred years. Locock introduced bromide in the treatment of epilepsy in 1857. Belgrave wrote in 1868 on its effect on epileptic attacks and concommitant insanity. In 1868 Holm observed reduction of the frequency of seizures at the same time as psychotic symptoms or just dysphoria. In 1875 Voisin described a dose‐dependent intoxication with psychosis and/or neurological signs. Stark in 1875 and Bannister in 1881 were the first to clearly describe the antagonism between epileptic seizures and psychotic symptoms, an antagonism or conversion described by many authors, both in cases with high and low dosage, and with and without intoxication. Thus, the title of this paper should be answered in the affirmative. Bromide has been used as a sedative and has rarely caused intoxication. Thus the presence of epilepsy is not a condition for the development of bromide intoxication. A case with epilepsy and fatal massive bromide intoxication is reported. It is discussed whether the pathological findings give support to Wolf's hypothesis of latent epileptic activity in subcortical pathways during “normalization”;. 相似文献
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Gunnar Rudberg 《Symbolae Osloenses / auspiciis Societatis Graeco-Latinae》2013,87(1):148-152
Like many of his contemporaries, Montaigne quotes abundantly from classical sources. But unlike most sixteenth-century writers, he does not use his quotations primarily as a source of authority or as rhetorical ornament. He deploys them in such a way as to make his readers take note not only of the quotation itself but also of its original context. He thus engages in a much deeper and more complex dialogue with his sources, one which may be regarded as a form of cross-cultural communication. As such, his quotation practice illustrates a fundamental (but often overlooked) feature of human communication: a great part of the information transmitted through an utterance or a text is communicated implicitly.1 2 相似文献
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Scripsit Gunnar Rudberg 《Symbolae Osloenses / auspiciis Societatis Graeco-Latinae》2013,87(1):105-111
In view of certain recent trends in Vergilian criticism the function of his imitation is still an open issue in at least one important respect. The author discusses some instances where critics have posited allusions running counter to the surface meaning of the text, such as Aen. 6.460 (‐ Cat. 66.39); 4–412.lb (‐Ap. Rhod. Arg. 4.445); 8.394 (‐ Lucr. 1.34); 4.149 (‐ Il. 1.46). Instead of integrating into Vergil's text an alien, sometimes even subversive, voice, it is more satisfying to understand such cases on the basis of the general hallmark of Vergilian imitatio, its ability to transform influences and assimilate even incongruous elements. 相似文献
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In the year 1900, Sweden probably had the oldest population in the contemporary world. It was also the first nation to implement a universal pension system in 1913. The universal character in early social legislation has certainly been decisive for the development of the Swedish welfare state. This alternative has not been self-evident. Why did the reforms turn universal, when the continental model, the Bismarck social security system, was exclusively directed at industrial workers? Research has concentrated on demographic factors and growing demands for social security, or on the fact that Sweden was still a predominantly rural society with about 2,400 local authorities. This article examines the development of social legislation in the light of local government expenditures and incomes, and suggests an overlooked possibility: the formulation of the first universal national social security reform was a redistributional response to uneven distribution of incomes and general expenditures among the rural districts in Sweden. 相似文献