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Despite the importance of the Clovis–Folsom transition for understanding the history of western North America, its spatiotemporal dynamics remains unclear. Here we report a three-part study in which we investigated the transition using radiocarbon dates from Clovis and Folsom sites. In the first part of the study, we used dates from Folsom site-phases to determine when and where Folsom originated. In the second part of the study, we employed Clovis and Folsom dates in analyses designed to determine whether Folsom spread via demic diffusion or cultural diffusion. In the third part of the study we investigated the velocity of the Clovis–Folsom transition. The analyses suggest that Folsom first appeared around 12,800 calBP in the northern High Plains and spread north and south from there. They also suggest that the spread of Folsom was, at least in part, the result of population expansion. In addition, the analyses indicate that the spread of Folsom was relatively fast for a prehistoric diffusion but well below the maximum velocity that has been estimated for such events. These findings, in turn, have implications for the hypotheses that have been put forward to explain the Clovis–Folsom transition. They refute the idea that the Clovis–Folsom transition resulted from an extraterrestrial impact over northern North America at 12,900 ± 100 calBP but are consistent with the alternative proposal that the transition was a response to climate-driven environmental change.  相似文献   
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A 62 year‐old contemporary white female diagnosed with metastatic carcinoma of the breast was examined after skeletonisation. She never received chemical, hormonal or radiation therapy. Because of the confirmed clinical diagnosis, lack of medicinal intervention, and quality of bone preservation, this specimen provides a comparative standard for metastatic carcinoma and differential diagnosis of idiopathic dry bone pathology. We detail gross and radiographic bone response to this disease and differentially diagnose the skeleton against Langerhans cell histiocytosis and multiple myeloma, conditions capable of modifying bone in characteristic patterns that may mimic metastatic carcinoma. Copyright © 2006 John Wiley & Sons, Ltd.  相似文献   
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