Pineal gland,perennial puzzle

Abstract

Since antiquity this tiny intracranial appendicular organ has aroused sexual connotations and denials. Controversial and enigmatic, it played a significant part in the development of endocrinology and even neurosurgery. What was its histology, what was its role as a gland so intimately attached to the brain? What did comparative anatomists make of it in the light of its function as a ‘third eye?’ Mysticism and the famous Cartesian apothegm placed it in the center of Eastern and Western approaches to the mind‐body problem and to mental disorders. The latter were connected with the common calcifications, so helpful in the radiological diagnosis of brain shifts due to mass lesions. Undefeated, even spurred by continuing uncertainties, researchers keep looking into this ‘photo‐neuro‐endocrine transducer.’     

Fritz Lewy and His Bodies

Attention is drawn to the neuronal inclusion bodies in Parkinsonism and the dementia described by F. Lewy in 1910, resulting in his eponym, as well as to his academic career and participation in two world wars on opposite sides.     

The diary of William MacEwan: Part II

This instalment of the Diary describes the first stage of the journey from Quilimane to the interior, then the most convenient and practicable way to the British territory of Nyasaland, and the way by which both people and goods entered and left that country. This is all changed ; the route has been abandoned by the African Lakes Corporation, and Maruru, the first place where the Diarist saw African village life, probably no longer exists. When the Diary is completed, it is hoped to publish an article describing the country MacEwan saw as it is at the present day. Much has been done to improve the condition of the natives under British rule since then, but it is more difficult to ascertain their condition under the Portuguese ; much more, however, remains to be done. Transport, of course, has been improved out of all comparison, and it will be interesting to compare it with the means by which MacEwan entered the then Darkest Africa—improvement which has taken place well within a single lifetime.