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Vedic pāthas     
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This review examines the history of discoveries that contributed to development of the dopamine hypothesis of schizophrenia. The origin of the hypothesis is traced to the recognition that neuroleptic drugs interfere with brain dopamine function. This insight was derived from two distinct lines of research. The first line originated from the discovery in 1956 that reserpine depletes brain serotonin. This finding resulted in a sequence of studies that led to the discovery that brain dopamine is involved in neuroleptic-induced extrapyramidal motor disturbances. The second line of research was aimed at determining the mechanism of action of psychomotor stimulants. This research produced evidence that stimulants directly or indirectly activate brain dopamine receptors. Because nonreserpine neuroleptics such as chlorpromazine block stimulant-induced movement, these findings suggested that neuroleptics were dopamine antagonists. Most previous accounts of the development of the dopamine hypothesis of schizophrenia emphasize the first line of research and ignore the second.  相似文献   
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Fourteen glass objects recovered from excavations at the ancient city of Tall Zirā‛a, Jordan, were analysed using laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) to determine the period and origin of manufacture. The composition of glasses manufactured in the Late Bronze Age (LBA) and Iron Age are distinctly different, therefore major element analysis can be used to distinguish between the groups relatively easily. The LA-ICP-MS analysis provided quantitative trace element data which were used to determine the provenance of those glasses identified as LBA. This research discusses the implications of the presence of both Egyptian and Mesopotamian LBA glasses and examines the varying compositions and colour strategies employed in both the LBA and Iron Age objects. Specifically, glass in the LBA was considered to be one of the highest status items attainable, playing an instrumental role in diplomatic gift-giving. When considered with the archaeological information, the significance of these finds at Tall Zirā‛a indicates that this city was a settlement of high status, not primarily a convenient trading stop on the Transjordan route.  相似文献   
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Résumé  L'article s'attache à dégager le fil rouge qui relie les réflexions de Wilhelm Gottfried Leibniz sur les jeux de société à la théorie des jeux, telle qu'on la trouve dans l'ouvrage de John Von Neumann et Oskar Morgenstern. L'itinéraire décrit passe par les travaux de plusieurs mathématiciens du XVIIIe siècle sur différents jeux de hasard, pour aboutir aux recherches de quelques-uns des fondateurs des mathématiques modernes, comme Ernst Zermelo pour la théorie des ensembles et émile Borel pour la théorie des probabilités. II montre comment une analyse mathématique des jeux de société a débouché sur l'élaboration d'une grille générale d'analyse des phénomènes sociaux. Son cheminement révèle, en outre, la longue parenthèse du XIXe siècle où ce programme s'est trouvé abandonné et esquisse, en conclusion, quelques hypothèses pour l'expliquer. The paper strives to find the clue which links Leibniz' thoughts on parlour games to the mathematical theory of games in John Von Neumann and Oskar Morgenstern.Magna opera the way goes through the works of several XVIIIth century mathematicians on various games of chance to reach the research of some of the modern mathematics founders, as Ernst Zermelo for the sets theory and émile Borel for the theory of probabilities. The paper shows how a mathematical analysis of parlour games ends at a general framework to study the social phenomena. Its development also reveals how this research program has disappeared, all along the XIXth century, and suggests, in conclusion, some tentative explanations of this development. Une version préliminaire de cet article a été publiée dans la revue de l'Association historique des élèves du lycée Henri IV,Jeu et histoire, no spéc.:L'émoi de l'histoire, 25–26, printempsautomne 2002, p. 94–115.  相似文献   
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Tanzania Maasai began large‐scale urban labour migration in the mid‐1990s, impelled by livestock losses from disease, drought and land alienation. Although they were readily hired in cities as night watchmen and security guards, many urban citizens expressed condescending views of the migrants, typifying them as ‘unmodern’, and as curious young warriors who were lazy, naive, drunk and dirty. Interviews with about 200 Maasai proved these discursive characterizations to be largely incorrect. Although the State has tried over the last century to ‘develop’ and settle semi‐nomadic pastoralists, the Maasai image is widely used as part of an instrumentalist agenda, to advertise items from telephones to tourism. Lacking political or social capital, the migrants manipulate and reinforce Maasai identity by continuing to wear traditional garments (illkarash), and by engaging in practices that emphasize their difference from the ‘WaSwahili’, bolster cohesion and solidarity among themselves, and increase their chances of urban employment.  相似文献   
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