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Genome editing — a plant-breeding technology that facilitates the manipulation of genetic traits within living organisms — has captured the imagination of scholars and professionals working on agricultural development in Africa. Echoing the arrival of genetically modified (GM) crops decades ago, genome editing is being heralded as a technology with the potential to revolutionize breeding based on enhanced precision, reduced cost and increased speed. This article makes two interventions. First, it identifies the discursive continuity linking genome editing and the earlier technology of genetic modification. Second, it offers a suite of recommendations regarding how lessons learned from GM crops might be integrated into future breeding programmes focused on genome editing. Ultimately, the authors argue that donors, policy makers and scientists should move beyond the genome towards systems-level thinking by prioritizing the co-development of technologies with farmers; using plant material that is unencumbered by intellectual property restrictions and therefore accessible to resource-poor farmers; and acknowledging that seeds are components of complex and dynamic agroecological production systems. If these lessons are not heeded, genome-editing projects are in danger of repeating mistakes of the past.  相似文献   
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ABSTRACT In this paper an attempt is made to measure the cultural industries in a cross‐national context. The paper starts with a discussion of the definition and delineation of the term the ‘cultural industries’. It is argued that a large range of goods and services may be considered to be cultural industry products and that it is important to place the production and exchange of such products in the context of an industrial systems approach. Following this the concept is operationalised using data on employment and firm activity from Denmark, Finland, Norway and Sweden. Results are presented which suggest that overall growth in both employment and firm numbers has been especially strong in the cultural industries. However, interesting differences between the countries emerged from the data. Thus regional dimensions are then examined resulting in the finding that in all four countries cultural industries have a strong attraction to urban areas but an even stronger propensity to agglomerate. It is suggested that the spatial dynamics observed may be key to the development of the industries' competencies and success. In summary the paper presents results of extensive data analysis that show the cultural industries' important contribution to Scandinavian economies and labour markets.  相似文献   
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Geographical Information Systems (GIS) provide an essential element in modern paleoanthropological inquiry through their ability to integrate a diverse range of data within a multidimensional spatial framework which can be used for data storage, analysis and modeling. One of the challenges of creating such a framework is the integration of legacy and new data (collected with digital technologies) at large sites with a long history of research. The Sterkfontein Caves, located in the Cradle of Humankind, is the richest Australopithecus-bearing locality in the world and has been the focus of intense palaeoanthropological research for the past 80 years. A diverse range of spatial data has been collected over this history and future integrative research necessitates the development of a unified, cohesive 3D GIS framework. In this paper we describe three phases of work undertaken to implement such a framework and discuss the next steps in its development and utilization for spatial analyses.  相似文献   
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ABSTRACT

Scholarship continues to identify the Enlightenment with secularization, despite the theological tenor of much of the movement's canonical literature. This article proposes an explanation for such a dissonance, before addressing the matter more directly through the work of Baruch Spinoza and Pierre Bayle. The claim is that scholars have been unduly dependent upon theological commentary in reaching the fixed verdict of secularization, inferring ‘atheism’ and disenchantment from the polemical utterances of a privileged orthodoxy rather than the primary sources themselves. Seen apart from such controlling anathemas, icons of the radical Enlightenment such as Spinoza and Bayle emerge as deeply spiritual thinkers, challenging the theocratic assumptions of their age with theological certainties of their own, interrogating orthodoxy with a resolutely biblical rationality. The final section suggests the continuity of the eighteenth-century Enlightenment of Voltaire, Kant and Mary Wollstonecraft with the spiritual rationalism of the seventeenth century. If so many of the Enlightenment's landmark thinkers were inspired by religious ideas, the concept of a secular modernity must be open to revision.  相似文献   
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Adrián Curiel Rivera is a Mexican novelist, short-story writer and academic. In addition to his novels Vikingos (2012), A bocajarro (2008) and Bogavante (2000), and the collections of stories Día franco (2016) and Madrid al través (2003), he has published two substantial volumes of critical essays, Los piratas del Caribe en la novelística hispanoamericana del siglo XIX (2010) and Novela española y boom hispanoamericano (2006). In 2013 he published Blanco Trópico, an excoriating and often hilarious fictional account of life in the Mexican Academy in the wake of sweeping neoliberal reforms in the university sector, the nature and consequences of which will be all too familiar to many European and US academics. The book caused something of a storm in his native Mexico. In the following interview, which took place in the summer of 2016, he discusses the genesis of and reactions to the novel, but also touches on a broad range of social and literary issues which the book raises: globalization, publishing, the Mexican literary canon and its sacred cows, as well as the place of the campus novel and science fiction in the current Latin American literary landscape.  相似文献   
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Pigments appearing on ninth–twelfth-century AD-carved stucco, wall painting, and terracotta friezes excavated at Nishapur in north-eastern Iran were investigated by optical reflectance spectroscopy, micro X-ray fluorescence spectrometry (μ-XRF), X-ray diffractometry (XRD), micro-Raman spectroscopy (μ-Raman), and scanning electron microscopy (SEM). Many of the pigments identified including vermilion, red lead, hematite, limonite, carbon black, atacamite, calcite, and gypsum have been identified in previous studies of pigments used in later Islamic periods. However, a series of unusual pigments such as wulfenite, pyromorphite, phoenicochroite, and jarosite were also found in the present study. The association of kaolinite and alunite with limonite and other Fe-bearing yellow pigments points to a local provenance for these pigments. In addition, the presence of orpiment in the vermilion may be indicative that the vermilion was artificially manufactured. These findings suggest that pigment use and manufacturing during the ninth to eleventh centuries in Nishapur was still in a trial-and-error stage and the palette known from the twelfth century onwards had not yet been systematized.  相似文献   
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