Social Networks and Actual Knowledge Flow in the Irish Biotech Industry

This paper presents an analysis of networks among small and medium-sized enterprises in the Irish biotech sector. The study applies social network analysis to determine the structure of networks of company directors and inventors in the biotech sector. In addition, on the basis of interviews, this article analyses the extent of actual knowledge flow through these industry networks. The paper makes both a theoretical and methodological contribution to innovation network research. In relation to theory, the findings of the social network analysis indicate that the extent and path of knowledge flow are influenced by both the type of knowledge in question and whether the network is of a formal or informal nature. Methodologically, the results of this paper raise questions about the application of social network analysis in innovation studies.     

Holocene climatic change and past Irish societal response

The extent to which North Atlantic Holocene climatic perturbations influenced past human societies is an area of considerable uncertainty and fierce debate. Ireland is ideally placed to help resolve this issue, being occupied for over 9000 yr and located on the eastern Atlantic seaboard, a region dominated by westerly airflow. Irish bog and lake tree populations provide unambiguous evidence of major shifts in surface moisture through the Holocene similar to cycles recorded in the marine realm of the North Atlantic, indicating significant changes in the latitude and intensity of zonal atmospheric circulation across the region. To test for human response to these cycles we summed the probabilities of 465 radiocarbon ages obtained from Irish archaeological contexts and observe enhanced archaeological visibility during periods of sustained wet conditions. These results suggest either increasing density of human populations in key, often defensive locations, and/or the development of subsistence strategies to overcome changing conditions, the latter recently proposed as a significant factor in avoiding societal collapse. Regardless, we demonstrate environmental change is a significantly more important factor in influencing human activity in the landscape than has hitherto been acknowledged.     

Two cases of leprosy from Žatec (Bohemia), dated to the turn of the 12th century and confirmed by DNA analysis for Mycobacterium leprae

The leprosy known today primarily from tropical areas was a relatively common disease in European Middle Ages. This article describes two skeletons bearing palaeopathological indications of leprosy from a cemetery at ?atec in North-West Bohemia (Czech Republic). The archaeological context clearly shows that these individuals were buried prior to the second decade of the 12th century, and most probably in the second half of 11th century. This rules out the possibility that these individuals might have contracted the disease in connection with the Crusades, in which a Bohemian contingent under Prince Vladislav II participated from 1141 to 1142. Molecular genetic methods were applied to detect specific DNA fragments of the causative agent of leprosy, Mycobacterium leprae. The nasal concha of one individual yielded DNA that could be directly sequenced after isolation and amplification. The vertebral body of the second individual, on the other hand, did not provide DNA of sufficient quality for direct sequencing and only weak amplification was detectable. The morphological and genetic analyses both indicate that leprosy existed prior to the Crusades in medieval Bohemia, albeit that its prevalence was probably not as great as in northern or western Europe.     

An Iron Bastard Minion Drake Extraordinary by John Browne from the Pinnace Swan (1641–53)

A small iron gun recovered from the wreck of the Caroline warship Swan has been identified as a drake, a lightweight tapered-chamber design dating from the 1620s. It is the only known cast-iron example of such a piece made by John Browne, gunfounder to Charles I, who was the leading figure in its development and manufacture in England. The gun was found together with an associated carriage, port-lid, and case shot appropriate to its calibre.
© 2004 The Nautical Archaeology Society     

The rise and demise of the Irish and Scottish computer hardware industry

This paper examines the dynamics of the computer hardware industry in Ireland and Scotland in a global context, from its inception in the late 1950s to the present. It provides a detailed account of plant openings and closures in both the system assembly and the component manufacturing segment. It describes the development of the computer hardware industry from mainframe assembly, through minicomputer assembly to microcomputer assembly and the shift of system assembly and component production activity to the Far East and Eastern Europe since the mid-1990s. The developments are analysed in terms of Schoenberger's (1997) model of concentrated deconcentration in the context of time-based-competition. It is shown that the model, with substantial qualification, fits the developments since the 1980s.     

Does size of local labour markets affect wage inequality? a rank-size rule of income distribution

The questions addressed in this paper are: (i) does wage inequalityincrease with local population size, and if so, (ii) what arepossible factors behind this increase? In a cross-section analysisof Swedish local labour markets using unique full populationdata, the article shows that urban scale, i.e. size of localpopulation, has significant positive effects on wage inequality.Testing for potential explanations, labour market diversification,human capital, migration, age structure and employment are shownto be significantly associated with inequality. Given theseeffects, the article raises the question of how to understandand incorporate scale effects into models of long-term changein wage inequality.