Cajal's Views on the Nobel Prize for Physiology and Medicine (October 1904)

In this report we present and discuss an unpublished letter written by Santiago Ramón y Cajal in October 1904 in relation to his possible nomination for the Nobel Prize for Physiology and Medicine. This letter shows that Cajal was aware of his previous nominations for the Prize. He was convinced that these nominations had not been successful because neither anatomy nor histology were among the sciences included in the Nobel Statutes' definition of Physiology or Medicine. He gives a list of the merits he thought might be used for a new nomination, which included only works concluded during the previous five years.     

Periostitis and osteolysis in a medieval skeleton from South‐West Hungary: (Leprosy,treponematosis, tuberculosis or hypertrophic osteoarthropathy) A diagnostic challenge!

This paper uses macroscopic and radiological examinations to provide differential diagnoses of pathological lesions in the well‐preserved skeleton of a young male from the medieval site of Zalavár in South‐West Hungary. Macroscopic inspection of the skeleton revealed conspicuous thickening of the tibiae and fibulae with ‘tree bark’ appearance of the cortex. Periosteal proliferations are also found on the calcanea and on the posterior part of the femora. The metatarsals showed bony proliferation and bone dissolution. No alteration of the axial skeleton or the skull was noted. Radiographs showed thickening of the cortex of tubular bones due to a multilayered type of periosteal apposition. The likelihood of these symptoms being the result of melorheostosis, hypervitaminosis A, fluorosis, thyroid acropachy, endosteal hyperostosis, tuberculosis (TB), hypertrophic osteoarthropathy (HOA), treponematosis and leprosy is reviewed. None completely explains the entire spectrum of pathological lesions in the current individual, but the individual may have suffered from two co‐existent diseases. As a clinical entity, the changes in the metatarsals are compatible with leprosy, whereas the periosteal proliferations of the lower limbs point to a diagnosis of HOA as a secondary syndrome. Thus, a combination of leprosy and TB is suggested as a potential diagnosis. Although not definitive, our differential diagnosis was able to exclude a number of conditions producing periosteal apposition. Copyright © 2011 John Wiley & Sons, Ltd.     

Comparison of Nonlinear Static Methods for the Seismic Assessment of Plan Irregular Frame Buildings with Non Seismic Details

The use of Nonlinear Static Procedures (NSPs) for the seismic assessment of plan irregular buildings is challenging. The most common pushover-based approaches have led to adequate results in regular buildings, and hence, there is a need to verify the validity of such methods on the assessment of irregular structures. In this article, four commonly used nonlinear static procedures (CSM, N2, MPA, ACSM) are applied on the assessment of two existing five- and eight-story plan-asymmetric buildings in Turkey. The accuracy of the different NSPs is evaluated through comparisons with the results derived from nonlinear dynamic analyses. The results are presented in terms of interstory drifts, normalized top displacements, lateral displacement profiles, chord rotations, base shear, and top displacement ratios. The performance of such procedures in evaluating the damage limitation according to the Eurocode8 is also verified. Special attention is given to the ACSM (Adaptive Capacity Spectrum Method) whose performance in 3D plan irregular buildings has recently been tested. Conclusions about the performance of each NSP are outlined at the end of the article.     

Wavelet-Based Damage Detection in Reinforced Concrete Structures Subjected to Seismic Excitations

The feasibility of using output-only model-free wavelet-based techniques for damage detection in reinforced concrete structures subjected to seismic loads is explored through the analysis of the results of a full scale shake table test of a reinforced concrete bridge column recently performed at the NEES Large High Performance Outdoor Shake Table. The evaluated approaches are based solely in the analysis of the acceleration time histories recorded in the structure. The viability of using numerical models to validate this type of damage detection methodologies is also evaluated. Wavelet analyses were capable of identifying the rebar fracture episodes and partially identified the frequency shifts in the structure as the inelastic demand increased. It was also found that, depending on the methodology employed, the use of numerical models to validate damage detection techniques can oversimplify the actual problem and/or induce spurious irregularities.     

Understanding interdisciplinarity in its argumentative context: thought and rhetoric in the perception of academic practices

ABSTRACT

The meaning and value of interdisciplinarity can be described in several, at times even contradictory, ways. Yet, little is known about how these play a role in individuals’ argumentation and everyday thinking. Drawing on Michael Billig’s rhetorical psychology, this paper explores how individuals draw on meanings, values, and connotations of interdisciplinarity to construct arguments and counter-arguments about this practice. This approach sheds light on the contradictions that surround interdisciplinarity, and thus on the rhetorical context in which its meaning is constituted. The value of rhetorical psychology for the study of interdisciplinarity is demonstrated through the analysis of the discourse of 27 interviews with researchers and administrators from a large British university. The analysis identifies 12 interpretative repertoires interviewees use to argue and to think about interdisciplinarity. Highlighting these repertoires and the contradictions between them is relevant for stimulating individuals’ reflexivity, critical thought, and decision-making regarding disciplinarity and interdisciplinarity.     

From Savages and Barbarians to Primitives: Africa,Social Typologies,and History in Eighteenth–Century French Philosophy

This article describes the conceptual framework (what I call a “style of reasoning”) within which knowledge about Africa was legitimized in eighteenth–century French philosophy. The article traces a shift or rupture in this conceptual framework which, at the end of the eighteenth century, led to the emergence of new conditions for knowledge legitimation that altered Europe’s perception of Africa. The article examines these two conceptual frameworks within the context of a discussion of the social theory of the time, which categorized Africans first as savages, and then, with the advent of our modern “style of reasoning,” as primitives. The argument used to demonstrate this change in categorizations is historical. (In the terminology of Michel Foucault, the paper is an “archaeological” investigation of knowledge about Africa.) The greater part of the article analyzes in detail the principal social theory of Enlightenment philosophy, the stadial theory of society, with the aim of demonstrating how it determined what could be affirmed about Africa. The shift in the perception of Africans from savages to primitives involved an epistemological change in how societies were grasped. The article provides a greater understanding of the constitution of Africa as a cognitive construct, which is not only of theoretical concern; this construct shaped Europe’s intervention in Africa, and continues to influence what we believe Africa is and should become.     

Revisiting the Epipalaeolithic-Neolithic Transition in the Extreme NW of Africa: The Latest Results of the Chronological Sequence of the Cave of Kaf Taht el-Ghar (Tétouan,Morocco)

African Archaeological Review - This study focuses on the chronostratigraphic sequence of the Cave of Kaf Taht el-Ghar (Dar Ben Karrich, Tétouan, Morocco) excavated in 2012 in the framework of...     

The manufacturing process of 3rd millennium BC bone based incrusted pottery decoration from the Middle Guadiana river basin (Badajoz,Spain)

The aim of this study is to present the manufacturing process developed on 3rd millennium BC white incrusted pottery from the middle Guadiana River basin (Badajoz, Spain), alongside the analytical procedure developed to determine the nature of these incrustations. The analytical procedure developed in this paper will assess the nature of these incrustations as burnt bone and in fewer cases as calcium carbonate, turning upside down the usual tendency for the Iberian Peninsula, where calcium carbonate has been the only kind of incrustation identified up until now. The analytical facilities used are: SEM-EDX, XRF microprobe, XRD and FTIR. The assessment of the nature of the incrustations as burnt bone has been a hazardous task and it has been necessary to develop a procedure using several analytical techniques and reference materials.