A Probable Case of Thalassemia Intermedia from Tell Masaikh,Syria

In this report, we describe the first potential case of hereditary anaemia from the Middle Euphrates valley (Syria). The skeletal changes identified in the studied specimen were consistent with marrow hyperplasia, and the distribution, especially the involvement of the facial bones, the sternum and ribs, was suggestive of thalassemia. The identified haplotype indicates M4b1 haplogroup suggesting that the analysed specimen was either a newcomer from Asia or a descendent of Asian origin in the maternal line, most likely from the Indian Peninsula where characteristic mutations of mtDNA can be identified today. The genetic data might explain a case of thalassemia in the Syrian lower Euphrates valley. Copyright © 2015 John Wiley & Sons, Ltd.     

The White Shark (Carcharodon carcharias) in the Ancient Peruvian Ceremonial Centre of Huaca Pucllana

New data regarding the white shark (Carcharodon carcharias) at the archaeological complex Huaca Pucllana (200–700 ad ) are presented on the basis of the recent discovery of teeth in ritual offering features. Previous information of this species from fossil, archaeological and modern records is reviewed. The use of the white sharks as an El Niño indicator is rejected. Past and present white shark distribution in the South East Pacific is reviewed, and the extermination of pinniped colonies as a factor in the poor modern record is discussed. Copyright © 2014 John Wiley & Sons, Ltd.     

Did Children in Medieval and Post‐medieval Poland Suffer from Scurvy? Examination of the Skeletal Evidence

Late‐medieval and post‐medieval writings report that scurvy was a widespread condition in medieval and early historical Poland. Archaeological and historical data indicate that the diet of children was based on foods poor in vitamin C and contained small amounts of raw plant products. Also, historians emphasise that in medieval and post‐medieval Poland, there were seasonal fluctuations in food availability, frequently accompanied by poor harvests. Both resulted in long periods of poor nutrition, which affected children most severely. The aim of this study was to investigate skeletal manifestations of scurvy in subadult remains from medieval and post‐medieval Poland. Following standards described by Ortner and colleagues, anatomical sites pathognomonic of scurvy in subadults (<17 years) were assessed for abnormal porosity and hypertrophic bone among skeletons excavated from three sites: Ostrów Lednicki (dated to the 11th–14th centuries AD), Cedynia (10th–14th centuries AD) and Słaboszewo (14th–17th centuries AD). In total, 3.6% of all examined children were found to bear traces of vitamin C deficiency. The prevalence of scorbutic lesions was 4.5% for Cedynia, 2.6% for Ostrów Lednicki and 3.6% for Słaboszewo. The majority of affected children were less than 7 years of age. Scurvy was likely more widespread in the living populations than it appears from the calculation of skeletal markers, because some individuals might have recovered or died before obvious traces became apparent. Also, in some children, scurvy might not have reached an advanced stage, identifiable in the skeletal material. The prevalence of scurvy reflects not only dietary patterns but also food storage and preparation techniques adopted in the Polish territories during the Middle Ages, which contributed to low intakes of vitamin C. Copyright © 2015 John Wiley & Sons, Ltd.     

Neonatal Mortality,Young Calf Slaughter and Milk Production during the Early Neolithic of North Western Mediterranean

The North‐Western Mediterranean witnessed a rapid expansion of farmers and their livestock during the Early Neolithic period. Depending on the region, cattle played a more or less important role in these communities; however how these animals were exploited for their milk is not clear. Here we investigate calf mortality to determine indirectly whether cattle dairying was practised by Early Neolithic stock herders. Age‐at‐death (AtD) frequencies for calves from two sites: Trasano (Italy, Impressa culture: 7–6^th millennium BC) and La Draga (Spain, Cardial culture: 6^th millennium BC) were estimated from dental eruption and development stages, and measurements of un‐fused post‐cranial material. Adult age classes are well represented in the dental AtD frequencies and were interpreted as the result of the slaughter of prime beef and retired lactating females. For calves aged less than 12 months, there was no statistical difference in the AtD frequencies based on dental and post‐cranial material indicating that the data is a good representation of the mortality patterns of calves, either natural or deliberate. At both sites there was a strong mortality peak at 3–6 months in all AtD profiles. At La Draga, this peak was clearly differentiated from a peak at 0–1 month, which can be interpreted neonatal mortality possible a consequence of the birthing season coinciding with the end of winter during more humid climatic conditions that at present. The deliberate slaughter peak around 3–6 months is discussed, and we propose that stock herders controlled the mortality of infant classes, possibly in response to variable external environment pressures while maintaining animal productivity. Copyright © 2014 John Wiley & Sons, Ltd.     

Palaeopathological evidence of infectious disease in skeletal populations from later medieval Serbia

Published data on palaeopathology are limited from the area of Serbia. This paper provides evidence for infectious disease in 1617 skeletons from eight Medieval Serbian cemeteries. Two hundred and three individuals were analysed by the first author and data on the remaining skeletons were derived from previous published work. A total of 23 adult individuals, and no non‐adults, had evidence of infectious disease. Historical data on infectious disease at that time are considered, particularly leprosy, treponemal disease, and infections affecting only the soft tissues, such as the plague, dysentery, smallpox and rabies, and the results of the analyses compared, with discussions on the limitations of the study. Copyright © 2001 John Wiley & Sons, Ltd.     

Review Article: Nationalisms,National Identities and Nation States: Gendered Perspectives

Books reviewed in this article: Nira Yuval‐Davis, Gender & Nation Lois West (ed.), Feminist Nationalism Rick Wilford and Robert L. Miller (eds.), Women, Ethnicity and Nationalism: The Politics of Transition Cynthia Cockburn, The Space Between Us: Negotiating Gender and National Identities in Conflict     

Rickets and child abuse: the case of a two year old girl from the 4th century in Lisieux (Normandy)

The burial of a child of two years of age from the 4^th century site of Lisieux‐Michelet (Calvados, France) was examined for bone hyperplasia and a variety of mechanical deformations recognized in association with skeletal trauma. Results of DNA analysis of bone using the PCR method identified this child as female. Microscopic features of the teeth (interglobular dentine) and a sample taken from the tibia conclusively determined that this child suffered from vitamin D‐resistant rickets and possibly X‐linked hypophosphataemic rickets as its most common form of occurrence. In addition, evidence for child abuse is suspected based on the presence of cranial and tooth fractures and the appearance of successive plaque‐like endocranial (meningeal) appositions. This is the first palaeopathological report of child abuse in antiquity. Copyright © 2002 John Wiley & Sons, Ltd.     

Well preserved non‐collagenous extracellular matrix proteins in ancient human bone and teeth

Ancient bones in a good preservation state, ascertained by microscopic techniques, conserve extracellular matrix proteins over thousands of years. With new techniques, intact extracellular matrix proteins from ancient bones and teeth are extracted and separated by one‐dimensional and two‐dimensional electrophoresis. Proteins were identified in Western blots by special antibodies against different human extracellular matrix (ECM) molecules of bone. We have confirmed different types of ECM human bone molecules such as osteonectin, osteopontin, and alkaline phosphatase with specific antibodies in human bone samples from different age groups. Additionally, we selected bone samples from different cultural time periods, such as the Middle Ages, the Bronze Age and the Late Pre‐Pottery Neolithic Phase (PPNB), and teeth from individuals from the Early Middle Ages and from the Late PPNB. The survival of intact extracellular matrix proteins in ancient bones and teeth dating from recent times to the Late PPNB, and reliable techniques to identify these proteins, present a great challenge to further research. A Match Set with PD‐Quest 7.2 shows that only 16% of protein spots in the teeth are also found in the bone of the same individual. In combination with the results of macro‐ and microscopic investigation, biochemical techniques will help us in obtaining a better understanding of bone and teeth in health and disease. Copyright © 2006 John Wiley & Sons, Ltd.