After the Exception: HIV/AIDS Beyond Salvation and Scarcity

Abstract: Access to treatment for HIV/AIDS became a flashpoint for global justice struggles in the late 1990s. An expanding international response, premised to a significant extent on the idea of HIV/AIDS as an exceptional global problem, has since delivered treatment, care and prevention to growing numbers of people. HIV/AIDS exceptionalism, however, has increasingly been questioned, many aspects of the response have been critiqued and donor funding has started to decline. I argue that, having been framed as an exceptional humanitarian emergency, the question of HIV/AIDS as a global problem is increasingly located within a discourse of scarcity. Tracking the growing entanglement of global HIV/AIDS relief with neoliberal governmentality and the emergence of something I term therapeutic neoliberalism, I argue that the shift from a rationality of salvation to one of administration poses new challenges for global health activism. Questioning the discourse of scarcity remains essential to an alternative global health agenda.     

Anglo-American Relations: End of a Special Relationship?

Obama's election in 2008 as the United States’ first self-styled Pacific President drew a hearty round of ‘end of the affair’ editorials about Anglo-American relations. His first term was littered with ‘snubgates’, serious irritations in policy areas regarded as being core to the special relationship, and indications of an accelerating US departure from Europe with his premier foreign-policy strategy declared to be a pivot to Asia. His return for a second term in 2013 augers a continuation of first-term adjustments in US foreign policy and greater domestic focus given a divided Congress and a bitterly split and war-weary United States with domestic priorities to the fore. Doomsayers - or so-called terminalists - have been repeatedly gainsaid by the Lazarus-like quality of the relationship in the past but can the Anglo-American special relationship survive in the Obama environment? This article suggests it can and sets out the author's rather unfashionable argument in four parts: the weight of history; the canons of international-relations theory; the importance of considering interest and sentiment in explaining the special relationship's resilience; and a relativist argument that suggests the United States still really does have no better ally than the United Kingdom.     

Historical Development of the Dopamine Hypothesis of Schizophrenia

This review examines the history of discoveries that contributed to development of the dopamine hypothesis of schizophrenia. The origin of the hypothesis is traced to the recognition that neuroleptic drugs interfere with brain dopamine function. This insight was derived from two distinct lines of research. The first line originated from the discovery in 1956 that reserpine depletes brain serotonin. This finding resulted in a sequence of studies that led to the discovery that brain dopamine is involved in neuroleptic-induced extrapyramidal motor disturbances. The second line of research was aimed at determining the mechanism of action of psychomotor stimulants. This research produced evidence that stimulants directly or indirectly activate brain dopamine receptors. Because nonreserpine neuroleptics such as chlorpromazine block stimulant-induced movement, these findings suggested that neuroleptics were dopamine antagonists. Most previous accounts of the development of the dopamine hypothesis of schizophrenia emphasize the first line of research and ignore the second.     

The Myth of Reserpine-Induced Depression: Role in the Historical Development of the Monoamine Hypothesis

For five decades it has been generally accepted that reserpine, an antihypertensive and antipsychotic drug, causes depression. The discovery that reserpine depletes brain monoamines was an important factor in the development of the monoamine hypothesis of depression, and it continues to be widely cited in support of this hypothesis. The present paper argues that, contrary to prevailing belief, reserpine is not depressogenic. The reason for perpetuation of this myth is reluctance to discard the monoamine hypothesis. This hypothesis ushered the modern biochemical paradigm into psychiatry and is still of great importance. It serves as a heuristic to guide research, it enhances psychiatry’s prestige, and it helps to validate and promote drug therapy for depression and other mental disorders.     

Notes and news from all over India

Allen G. Noble and Ashok K. Dutt, Editors. India: Cultural Patterns and Processes. Westview Special Studies on South and Southeast Asia. Boulder, Colorado, 1982. xiv + 378 pp. $18.00.     

Editor's Introduction

Hannaford, Ivan. Race: The History of an Idea in the West. Washington, DC: The Woodrow Wilson Center Press, 1996. xvii + 448 pp. including chapter references and index. $19.95 paper.

Hoberman, John. Darwin's Athletes: How Sports Has Damaged Black America and Preserved the Myth of Race. New York: Houghton Miffin, 1997. xxvi + 341

Williams, Vernon J., Jr. Rethinking Race: Franz Boas and His Contemporaries. Lexington: University Press of Kentucky, 1996. ix +152 pp. including chapter references and index. $34.95 cloth.

Wolpoff, Milford and Rachel Caspari. Race and Human Evolution: A Fatal Attraction. New York: Simon and Schuster, 1997. 463 pp. including chapter references and index. $26.00 cloth.