Solomon Carter Fuller, M.D. (1872-1953): American pioneer in Alzheimer's disease research

The appointment of Alois Alzheimer to Emil Kraepelin's clinic and laboratory at the Royal Psychiatric Hospital, University of Munich in 1903 offered new opportunities for clinical and pathological studies of the brain. At the opening of the facility in 1904, Alzheimer selected five foreign visiting students as his graduate research assistants, among whom was an American, Dr. Solomon Carter Fuller. A glimpse of Fuller's background as an African-American (born in Liberia) at the turn of the century, his continuing research after leaving Germany in 1906, and his critical view of the Alzheimer dementia entity are recounted. He was held in high esteem as a practicing neuropsychiatrist and teacher in the Boston area.     

Dysfunctional domesticity: female insanity and family relationships among the West Riding poor in the mid-nineteenth century

"Dysfunctional domesticity" contributes to the growing reevaluation of the importance of the history of the family to understanding the history of insanity. Using patient case histories from the West Riding Pauper Lunatic Asylum, this article examines representations of family life among poor in England in the 1830s and 1840s. Among the so-called moral causes of insanity, family relationships held a prominent place. Female patients more than male patients had their mental illnesses attributed to their domestic circumstances: the poverty of their home lives, grief over a death of friends and family, love and marital relationships gone wrong, and violence in their homes. The case histories reveal that poor women experienced many pressures in the domestic sphere, and insanity may have been one way to escape dysfunctional domesticity.     

Theoretical change and therapeutic innovation in the treatment of syphilis in mid-nineteenth-century France

This article examines changes in the treatment of venereal disease in mid-nineteenth-century France in light of theoretical developments in the understanding of these diseases. It focuses on three theories of venereal disease: the orthodox theory of the "unity" of gonorrhea and syphilis; the physiological theory of Fran?ois Broussais, which essentially denied the actual existence of such a disease; and Philippe Ricord's new doctrine of venereal disease, a theory that is often credited with having established the distinction between syphilis and gonorrhea. The argument is that theoretical considerations played a major role in the evaluation of the relative merits of these theories and that any understanding of the appeal of Ricord's new doctrine must consider not only its pathological claims but its therapeutic implications as well. This was not, however, simply an instance of theory applied. These two aspects of Ricord's new doctrine, its pathology and its therapeutics, were inextricably bound up with one another, so that judgment of the one necessarily entailed judgment of the other. The argument is that therapeutic practice should not be seen simply as a downwind consequence of changes in the theoretical understanding of disease, but rather as an integral part of the process of change. These were the kinds of developments that led doctors to believe that French medicine was making very real progress at mid-century.     

Alexander the Great, the dahlia, and the tortoise

Some of the problems of establishing the cause of the death of Alexander the Great are like the attempts to find causes other than hysteria for Anna O.'s symptoms. The more general problem of using plausibility as a criterion of the truth of such reconstructions are illustrated by the arguments embedded in Tom Stoppard's Arcadia.