Urbanization,Place of Experiment And How the Electric Fish Was Caught by Emil Du Bois-Reymond

Laboratories, along with the researchers, organisms, instruments, and experiments associated with these places of investigation, are not isolated from the world beyond their physical and institutional boundaries. Both laboratories and the cities in which they are embedded are subject to change, as was most dramatically apparent in their dynamic and far-reaching transformation during the industrial revolution of the nineteenth century. Using the example of Berlin and the institutionalization of experimental physiology by Emil du Bois-Reymond, in this paper I study experimental work on frogs and fish in order to demonstrate how a city and a laboratory cooperate in the production of knowledge. Emil du Bois-Reymond's research on electric fish illustrates how an exotic organism and a laboratory came together in a city and how the research was driven by innovation and development in urban and industrial technology. Ongoing changes in the urban landscape entered du Bois-Reymond's workplace and became part of the material culture of his experimental physiology and his attempts to demonstrate that the electric fish discharge is fundamentally similar to the excitation of nerve and muscle.     

Alexander von Humboldt: Galvanism,Animal Electricity,and Self-Experimentation Part 2: The Electric Eel,Animal Electricity,and Later Years

After extensive experimentation during the 1790s, Alexander von Humboldt remained skeptical about “animal electricity” (and metallic electricity), writing instead about an ill-defined galvanic force. With his worldview and wishing to learn more, he studied electric eels in South America just as the new century began, again using his body as a scientific instrument in many of his experiments. As had been the case in the past and for many of the same reasons, some of his findings with the electric eel (and soon after, Italian torpedoes) seemed to argue against biological electricity. But he no longer used galvanic terminology when describing his electric fish experiments. The fact that he now wrote about animal electricity rather than a different “galvanic” force owed much to Alessandro Volta, who had come forth with his “pile” (battery) for multipling the physical and perceptable effects of otherwise weak electricity in 1800, while Humboldt was deep in South America. Humboldt probably read about and saw voltaic batteries in the United States in 1804, but the time he spent with Volta in 1805 was probably more significant in his conversion from a galvanic to an electrical framework for understanding nerve and muscle physiology. Although he did not continue his animal electricity research program after this time, Humboldt retained his worldview of a unified nature and continued to believe in intrinsic animal electricity. He also served as a patron to some of the most important figures in the new field of electrophysiology (e.g., Hermann Helmholtz and Emil du Bois-Reymond), helping to take the research that he had participated in to the next level.     

Facts and Philosophy in Neurophysiology. The 200th Anniversary of Johannes Müller (1801–1858)

Johannes Müller was the founder of the first school of physiology in Germany. His anatomical, morphological and physiological research as well as his epistemological view of scientific medicine opened the way to a deeper understanding of the structure and the function of the organism. With important discoveries like the law of sense energy, the reflex movement and the definition of different organic stimuli, he enriched the knowledge of neuroanatomy, neurophysiology and sensory physiology and smoothed the way to an experimental physiology. All his famous students like Hermann von Helmholtz, Emil Du Bois-Reymond, Ernst Brücke, Jakob Henle, Robert Remak, Rudolf Virchow and Ernst Haeckel solved many crucial research problems, which Müller identified and pointed out to them as open questions, due to the insufficient methods of investigation. Müller's research method, epistemological view of biological sciences, and his open-minded personal style encouraged the development of new methods adapted to particular problems.     

Nightscapes of Play: Enjoyment of Architecture and Urban Space through Bicycling

Anti‐automobile, anti‐capitalist, and pro‐environmental worldviews are known to shape bicyclists’ right to the city demands. This research uncovers another layer of their radical engagement with the city: playful enjoyment of architectural structures and urban space, using the case study of Midnight Mystery Ride, a community bicycle ride taking place in the middle of the night once a month in several cities around the world. Through theoretical lenses of play and rhythmanalysis, I argue that bicyclists at night take over spaces built with exchange vale in mind and introduce use value in the same spaces. Interviews with bicyclists demonstrate how their unconventional use of space questions separation from natural rhythms and nature. I demonstrate that their nighttime use of the city is also a critique of how urban space is organised largely for profit and discipline and of how the human and playful potential of urban space are not fully realised.     

Bernstein's long path to membrane theory: radical change and conservation in nineteenth-century German electrophysiology

This article aims at illustrating the historical circumstances that led Julius Bernstein in 1902 to formulate a membrane theory on resting current in muscle and nerve fibers. It was a truly paradigm shift in research into bioelectrical phenomena, if qualified by the observation that, besides Bernstein, many other electrophysiologists between 1890 and 1902 borrowed ideas from the recent ionistic approach in the physical-chemistry domain. But Bernstein's subjective perception of that paradigm shift was that it constituted a mere reinterpretation of the so-called preexistence theory advanced by his teacher Emil du Bois-Reymond in the first half of the nineteenth century.     

Solomon Carter Fuller, M.D. (1872-1953): American pioneer in Alzheimer's disease research

The appointment of Alois Alzheimer to Emil Kraepelin's clinic and laboratory at the Royal Psychiatric Hospital, University of Munich in 1903 offered new opportunities for clinical and pathological studies of the brain. At the opening of the facility in 1904, Alzheimer selected five foreign visiting students as his graduate research assistants, among whom was an American, Dr. Solomon Carter Fuller. A glimpse of Fuller's background as an African-American (born in Liberia) at the turn of the century, his continuing research after leaving Germany in 1906, and his critical view of the Alzheimer dementia entity are recounted. He was held in high esteem as a practicing neuropsychiatrist and teacher in the Boston area.     

Neurocinematography in Pre-World War II Netherlands: The Magnus-Rademaker Collection

Historical films made by neuroscientists have shown up in several countries during past years. Although originally supposed to have been lost, we recently found a collection of films produced between 1909 and 1940 by Rudolf Magnus (1873–1927), professor of pharmacology (Utrecht) and his student Gysbertus Rademaker (1887–1957), professor of physiology (1928, succeeding Willem Einthoven) and neurology (1945, both in Leiden). Both collections deal with the physiology of body posture by the equilibrium of reflex musculature contractions for which experimental studies were done with animals (labyrinthectomies, cerebellectomies, and brainstem sections) and observations on patients. The films demonstrate the results of these studies. Moreover, there are films with babies showing tonic neck reflexes and moving images capturing adults with cerebellar symptoms following cerebellectomies for tumors and several other conditions. Magnus’ studies resulted in his well-known Körperstellung (1924, “Body Posture”) and Rademaker’s research in his Das Stehen (1931, “Standing”). The films probably had an educative and scientific purpose. Magnus demonstrated his films at congresses, including the Eighth International Congress of Physiologists (Vienna, 1910) and Rademaker screened his moving images at meetings of the Amsterdam Neurologists Society (at several occasions as reflected in the Winkler-Monakow correspondence and the Nederlands Tijdschrift voor Geneeskunde). Next to these purposes, the films were used to analyze movement and a series of images from the films were published in articles and books. The films are important historical sources that provide a portrait of the pre-World War II era in neuroscience, partly answering questions on how physicians dealt with patients and researchers with their laboratory animals. Moreover, the films confirm that cinematography was an important scientific tool in neuroscience research.     

国内外城市功能疏解研究进展

由于城市聚集效益的存在,城市功能不断向中心城区集聚,过多的功能集聚带来了一系列城市问题,城市功能疏解的研究亟待开展。文章首先从人口疏解和产业疏解两大模块以及土地利用变化方面对功能疏解的测度方法进行述评,并简要分析了功能疏解的必要性和动力机制;其次对国内外功能疏解的经验进行梳理;再次对功能疏解的成效进行评价;最后对国内外功能疏解研究内容进行述评。总体而言,与国外研究相比,国内研究起步较晚,但内容上与国外研究基本相似;然而在方法上国内研究目前仍以数量分析为主,缺乏相关测度模型的构建。随着国内城市功能疏解实践的推进,以及在中国特殊的土地和户籍等政策影响下,功能疏解的方法和理论研究将不断完善。     

Instrument transfer as knowledge transfer in neurophysiology: François Magendie's (1783-1855) early attempts to measure cerebrospinal fluid pressure

Fran?ois Magendie's (1783-1855) experimental model for measuring blood pressure in animals, which he developed in 1838, had a major impact on French physiology in the nineteenth century, especially upon Etienne-Jules Marey (1830-1904) in Paris. In due course it was also adopted by other European investigators, such as the Leipzig physiologist Carl Ludwig (1816-1895), and by clinicians who developed it into a major measuring tool. Historians of science, however, have paid hardly any attention to Magendie's further laboratory investigations conducted with the assistance of Jean-Louis Marie Poiseuille's (1799-1869) sphygmomètre (blood pressure meter). After having used the apparatus to conduct his experiments on a variety of blood vessels, Magendie also applied the sphygmomètre in 1840 to the ventricular system of the brain in order to measure cerebrospinal fluid (CSF) pressure. But the scope of this new procedure had yet to be defined: the new measuring device invited many speculative interpretations about the meaning of CSF flow for the physiology of the ventricular system in healthy and diseased brain function. As such, Magendie's experiments produced phenomena in very heterogeneous knowledge areas, and CSF measurement was situated at the interface of quite disparate investigative spaces regarding the structure and function of the brain. In his textbook Le?ons sur les Fonctions et les Maladies du Système Nerveux (Lectures on the Functions and Diseases of the Nervous System), Magendie described extending application of the measuring "apparatus of Poiseuille" from blood vessels to parts of the brain. The instrument thus became something of a liquidodynamomètre (liquor dynamometer), that paved the way for later applications, including (after 1896) diagnostic intracranial pressure (ICP) measurement by Theodor Kocher (1841-1917) and Harvey Cushing (1869-1939). The current paper focuses on the experimental contingencies that prompted the instrument transfer in Magendie's laboratory and opened up new epistemological perspectives for research in neurophysiology.     

全球化视角下的世界城市网络理论

城市诞生时就相互保持着联系,只有将城市纳入世界城市网络中才能正确把握城市产生和发展的本质。1980年以来在第三次全球化浪潮的背景下,世界生产要素和产品市场开始整合,世界城市的兴起是国际劳动分工在空间上的表达。Cohen、Friedmann、Sassen、Castells和Taylor等学者提出并发展了世界城市理论,世界城市网络理论已经成为研究城市问题的重要框架。联系数据的缺乏长期制约了世界城市网络的实证研究,二十世纪九十年代中期以来学者们创新性地解决了方法论的问题,对世界城市网络的各个层面进行了实证研究。     

后福特方式下城市产业空间格局和结构的演变——以广州服装产业为例

随着生产方式由福特制向后福特制演变,城市产业空间呈现出特有的格局变化,进而影响城市空间结构的变化.文章在构建后福特生产方式下城市产业空间格局和结构变化的理论框架的基础上,利用2008年和2018年广州服装企业数据,探究其空间格局和结构演变.研究结果表明:①广州服装产业空间格局演变符合后福特生产影响下的产业空间变化特征,...     

Contrasts between first-tier and second-tier cities in Europe: a functional perspective

Second-tier cities have been experiencing renewed interest within policy and research contexts, which is reversing a tradition of relative neglect due to the long-standing focus on large cities and capitals. This paper compares European second-tier and first-tier cities with regard to the presence of urban functions and how these are spread over their urban regions. The analysis shows the existence of a substantial ‘first city bonus’: a surplus of urban functions in first-tier cities which cannot be explained by their size or network embeddedness. We also show that second-tier cities are better served with urban functions in the absence of a dominant capital. In first-tier urban regions, the core municipality exploits the critical mass of the urban region to support its own functions, leaving that region functionally underserved. Second-tier cities lack this absorptive capacity, and their urban regions are endowed with more urban functions. These functional differences mean that second-tier cities demand a differentiated research and policy approach, in which city-regional integration becomes an important territorial development strategy. Rather than the dispersion process in first-tier cities leading to a ‘regionalization of the city’, integration in second-tier urban regions may be seen as a process of ‘citification of the region’.     

基于GIS的盐城城市内部空间结构演变分析

根据1984、1997、2003、2006年4个时相数据,运用GIS的空间分析方法,对盐城城市工业、居住、公共服务用地的空间分异特征进行分析,并利用多种景观格局指数,分析了三种功能用地的完整性、集聚性和异质性特征。结果表明:1984-2006年盐城城市内部空间结构演变过程可划分为集聚、分散、再集聚三个阶段,同时演变中存在"工业围城"、城市中心区的工业和居住用地比重偏大等问题。     

Knowledge Production,Urban Locations and the Importance of Local Networks

This paper analyses the relationship between knowledge production and urban locations in industrial design, a knowledge-intensive business service (KIBS). KIBS concentrate in urban locations. This is often explained by the co-location of client firms and market access in large cities. Recent research on knowledge production, however, reveals that knowledge productive networks are significant for both the competitiveness and location of KIBS. Thus, to understand the urban location of industrial design, it is important to analyse how knowledge production is organized within the industry. Industrial design is concentrated in urban locations, but most of its clients are located elsewhere. Hence, it seems that industrial design firms concentrate in urban locations mainly because their knowledge networks include specific types of formal and informal local social networks.     

„Die Photographie als Hülfsmittel mikroskopischer Forschung”︁? Joseph von Gerlach (1820–1896) und die frühen anatomischen Mikrophotographen

The Erlangen anatomist Joseph von Gerlach was one of the first medical researchers who used microphotography for their scientific aims in basic tissue research. Already in 1863, Gerlach published a famous handbook on the methodology of the microphotographic technique, entitled Die Photographie als Hülfsmittel mikroskopischer Forschung. Here, he discussed the technological, practical and epistemological standards and constraints of the newly introduced visualisation technique of scientific photography. The efforts and setbacks of Gerlachs' innovative approaches shall be characterised in the present paper. Furthermore, some of the most important arguments put forward by some of his peers are closely compared and thoroughly scrutinised. These anatomical and biological microscopists objected frequently to Gerlach's photographic approach as being "unscientific" or "insufficient" to support the growth of experimental morphology and neurohistological research. In his scientific self-defence, Gerlach developed important auxiliary arguments that display many facets of the epistemological discourse of 19th-century medical research, particularly on the question of how scientific objects should be visualised and identified in the experimental laboratory.     

长春市居住与工业空间演进的耦合性测度及影响因素

以长春市为研究对象,基于用地现状图等数据,借助ArcGIS软件,采用斑块聚合指数、标准差椭圆、核密度估计等研究方法,对1995-2013年长春市居住与工业空间演进的耦合性进行了测度,发现： ①长春市居住、工业与城市用地分布的“离散化”趋势明显,其中居住用地的斑块聚合指数波动幅度较大;②从居住与工业用地“中心-外围”分布特征来看,三环以内居住与工业用地呈现明显的“逆协同”演变规律,二者的用地密度变化表现出明显的差异性;③从居住与工业用地格局演进来看,二者布局的耦合度呈下降趋势。从成长路径依赖、政府调控引导、市场经济驱动、科技创新带动、空间主体的决策等六个方面分析了影响居住与工业空间演进耦合性的影响因素。     

A diasporic right to the city: the production of a Moroccan diaspora space in Granada,Spain

In this paper, I bring together ideas of ‘diaspora space’ and ‘the right to the city’ and empirically demonstrate how the formation of diasporas is frequently dependent on migrants attaining certain rights to the city. These rights, I argue, are conditioned and attained by the interplay of urban structural context with the place-making strategies of migrants. Drawing on 8 months of ethnographic fieldwork, I demonstrate that Moroccan migrants in Granada, Spain, have achieved a partial right to a neighbourhood of the city, producing a multi-sensory, self-orientalised diaspora space. First, I show that certain urban conditions in Granada provided a foothold for Moroccan migrants to begin to form a diaspora and transform urban space. Second, I demonstrate that through the mobilisation of a strategically self-orientalised cultural capital, the diaspora have partly appropriated the valuable history of Al-Andalus, a key component in the city’s tourist imagery. These factors and strategies have enabled Moroccan migrants to gain a right to have a visible presence in the city, a right to produce and transform urban space and a right to spatalise diverse identities – all key rights, I argue, in the formation of a diaspora.     

Neoliberalising the divided city

This paper examines the relation between ethno-nationalism and neoliberalism in urban space. Contrary to common views in urban studies, it argues that the ‘ethno-nationally divided city’ and the ‘neoliberal city’ are not antithetical, but that neoliberal nationalism is a new modality of urban conflict in a globalised world, which reshapes the relation between the local and the global and draws new urban geopolitics. By investigating practices of nation-branding in a divided city, this paper bridges different theoretical fields to shed light on an aspect of urban conflict that has largely been ignored by the literature on nationalism and urban divisions. It also complements existing research on neoliberal nationalism by emphasising the spatial and material aspects of nation-branding, and by showing how it can be used by competing ethno-national leaders to mobilise their communities and extend their control at the national and urban levels. By highlighting processes common to neoliberal and divided cities, this paper draws on recent calls within urban geopolitics to rethink current theoretical categories and labels attributed to cities. It develops this analysis by examining contemporary neoliberal urban policies in Skopje, Macedonia, which have become a new battlefield where interethnic conflicts unfold.