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K. Inoue W. Takigawa M. Sato M. Kumagai Y. Dodo K. Katayama 《International Journal of Osteoarchaeology》2005,15(3):186-195
Palaeopathology helps to define the migration of past diseases. Genetic and environmental factors play a role in the development of spondyloarthropathy (SpA). We report skeletal remains with SpA from the Jomon period in Japan. The skeleton is of a female who died at a young adult age. The skeleton had characteristic features seen in SpA as follows: (1) polyarticular arthritis; (2) erosions accompanying some bone formation; (3) enthesial ossification; and (4) periostitis in lower long bones. The findings suggest that SpA was present in prehistoric Japan before contact with European civilisation, and the present example of SpA is the oldest in Asia and the Old World. Copyright © 2004 John Wiley & Sons, Ltd. 相似文献
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Joël Blondiaux Anne Cotten Christian Fontaine Catherine Hnni Anne Bera Ren-Marc Flipo 《International Journal of Osteoarchaeology》1997,7(5):451-466
With continued archaeological discoveries of skeletal remains in the USA and Europe, discussion of the possible aetiology for recognized cases of symmetrical erosive polyarthropathy include the spondylarthropathies and rheumatoid arthritis. One skeleton from the fourth century site of Lisieux and a second from the eleventh century site of Rouen are characterized by numerous symmetrical marginal erosions, primarily involving the metacarpophalangeal and proximal interphalangeal joints. Results of maroscopic, microscopic and radiological examination are highly suggestive of a modern-day diagnosis of rheumatoid arthritis. These data are consistent with the presence of rheumatoid arthritis before the onset of the fourteenth century. © 1997 John Wiley & Sons, Ltd. 相似文献
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Koji Inoue Sinsuke Hukuda Masashi Nakai Kazumichi Katayama Jie Huang 《International Journal of Osteoarchaeology》1999,9(1):1-7
The antiquity of rheumatoid arthritis (RA) is still in dispute, due to the difficulty of conclusively differentiating peripheral polyarthritis, especially from spondyloarthropathy, in archaeological populations. In view of the importance of genetic factors in developing spondyloarthropathy and of the far lower prevalence of the disease in modern Japanese, a rarity of peripheral polyarthritis would be anticipated in the ancient Japanese population, given that RA had not been present there. One hundred and sixty adult Japanese skeletons of the late and final Jomon period (3400–2400 years bp ) were examined to find peripheral polyarthritis. There was one male skeleton with peripheral polyarthritis, showing marginal and surface erosions in the joints of the hands, feet, ankle and zygoapopheseal joints of the thoracic vertebrae. RA is suggested as the most probable cause of this pathology. This report raises the significance of further studies to consider whether more cases than anticipated exist in skeletal populations that would have been resistant to developing spondyloarthropathy. Copyright © 1999 John Wiley & Sons, Ltd. 相似文献
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This paper reviews evidence for the rare condition of porcine syndactyly. It describes eight archaeological examples from Britain, Northern Ireland and France. Syndactyly refers to the partial or complete fusion of two or more adjacent phalanges on the medio‐lateral border. The degree and character of fusion are variable, but phalanges frequently unite to create a single skeletal element. This condition has been identified by veterinarians, zoologists and naturalists in individuals and populations in a range of species, but in spite of substantial research on the condition in humans and to a lesser extent cattle, it remains relatively poorly understood in other mammals. Syndactyly is generally agreed to be primarily congenital in origin, although factors affecting its incidence remain far from fully understood. In light of the general paucity of discussion of specific conditions of animal palaeopathology, this paper presents an analysis of these newly discovered syndactyle pig specimens, offers a review of research with particular reference to pigs and discusses the etiology of the condition. Copyright © 2011 John Wiley & Sons, Ltd. 相似文献
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The rhinomaxillary syndrome consists of a group of maxillary bone changes, which may be present in part or in total, in lepromatous and near-lepromatous leprosy. The changes are a composite mixture of erosive, absorptive and proliferative bone reactions. The anatomical zones involved are the alveolar process of the maxilla, the anterior nasal spine, the palatine process of the maxilla, intranasal osseous structures, and the margins of the nasal aperture. 相似文献
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E. Haduch A. Szczepanek J. Skrzat R.
rodek P. Brzegowy 《International Journal of Osteoarchaeology》2009,19(5):593-612
A skeleton from a 16–18th century burial site in Krosno Odrzańskie, Poland, was examined using classical morphological, metric and macroscopic palaeopathological observations, as well as radiography and tomography of the skull and long bones. A wide variety of the observed bone deformations probably occurred as a consequence of past rickets and/or osteomalacia, whose primary cause may also have been chronic renal failure. Preservation of the bones enables a discussion of the cause of such pathological changes. The subject under study appears to be a very interesting example of an individual whose skeleton shows advanced pathological alterations associated with the subject's vitamin D deficiency, overall health conditions and relatively long lifespan. Copyright © 2008 John Wiley & Sons, Ltd. 相似文献
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Tony Waldron 《International Journal of Osteoarchaeology》1993,3(3):213-218
The distribution of osteoarthritis of the hands was studied in 101 skeletons from archaeological sites in England. The results are similar to those found in epidemiological studies of modern populations. Osteoarthritis of the hands was more common in females than in males, and in females tended to involve a greater number of joints. The distal and proximal interphalangeal joints were commonly affected, the former more frequently than the latter, but otherwise the disease was largely confined to the first ray of the hand, centred on the trapezium. It is concluded that the pattern of osteoarthritis in the hand has probably not changed greatly over several hundred years. 相似文献
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The transition from a hunting/gathering economy to an agricultural economy, beginning about 10,000 years ago, was accompanied by the development of specialised innovations including nomadic pastoralism. It was also associated with the emergence of increasingly sedentary human societies in which relatively large numbers of people lived in a crowded urban environment. The dynamic relationship between agriculture and urbanisation undoubtedly had a profound effect on evolutionary dynamics in developing complex human societies. By the beginning of the Early Bronze Age (EB IA, ca. 3300 BCE) an agricultural economy was well established in the region surrounding Bâb edh‐Dhrâ, located in the southeastern plain adjacent to the Dead Sea in Jordan. However, the site apparently did not begin to develop as an urban centre until EB IB. The objective of this paper is to explore what is known about the EB IA people of Bâb edh‐Dhrâ. The presence of infectious and metabolic diseases coupled with high infant mortality and low life‐expectancy at birth suggest a society at risk. Nevertheless the people were robust and give evidence of at least a moderately successful adaptation to the environment in which they lived. Published in 2007 by John Wiley & Sons, Ltd. 相似文献
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This study collects data from three major journals and analyses them in order to assess the recent (1997–2006) nature of the study of palaeopathology within Britain. It considers the types of study published (case, population or method), whether findings are integrated with other data, the particular ‘theme’ that is considered (diet, activity patterns, etc) and the particular pathological condition focused upon (metabolic, dental, etc). The findings show there is a move away from the traditional case study and an increase in the acknowledgement of the value of integrating data with wider information. There is also a bias towards certain ‘themes’ and pathologies, reasons for which are discussed. Copyright © 2009 John Wiley & Sons, Ltd. 相似文献
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The subject of this paper is the partial skeleton of an adult female, dating to ad 1420–1640, excavated from the church at the deserted village of Wharram Percy, North Yorkshire, UK. Lesions are described which are probably indicative of hyperparathyroidism. Copyright © 2001 John Wiley & Sons, Ltd. 相似文献
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Skin ulcers of the lower leg are known to cause both destructive and, more commonly, bone‐forming lesions. Typically, bone‐forming lesions in this disorder have clearly defined margins although there may be extensive reactive bone formation involving much or all of the adjacent diaphysis. These lesions are best described in patients from tropical areas, and in these environmental contexts, these are known as tropical ulcers, but leg ulcers can be caused by a variety of diseases and conditions, of which vascular insufficiency plays an important role among the elderly. The lesions are important clinically because of the disability associated with the ulcer and because of complications that can develop including osteomyelitis and cancer. In most cases, the bone lesions caused by ulcer are easily diagnosed in archaeological human skeletal remains and provide some insight into the prevalence of this disorder in antiquity. In this paper, we review the gross and radiological manifestations of bone lesions resulting from overlying skin ulcer in tibiae of 13 cases including archaeological and modern medically documented skeletons. In two of the cases, there is medical documentation regarding the presence of a chronic ulcer on the lower leg. The objectives of this paper were to explore the diversity of bone lesions associated with ulcers of the tibia and to provide an improved basis for the diagnosis of this disorder in human skeletal remains. Copyright © 2011 John Wiley & Sons, Ltd. 相似文献
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J. Blondiaux C. A. Baud N. Boscher-barr C. Dardenne N. Deschamps P. Trocellier L. Buchet 《International Journal of Osteoarchaeology》1992,2(3):241-244
Instrumental neutron activation analysis (INAA) of the bones of a 6th century case (AD ) of hypertrophic osteoarthropathy (HOA) showed high levels of Zn, Mn and K in the periosteal new bone. The concentration of Zn in the periosteal new bone appeared to be biogenetic in origin and connected with active mineralization processes in the abnormal bone tissue. Manganese and potassium concentrations were, at least partly, related to diagenetic processes. 相似文献
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Mastoiditis is a disease that follows otitis media and may lead to severe endocranial complications. Most studies on mastoiditis and middle ear diseases in archaeological skeletal remains are based on radiological investigations. The following study describes the morphological changes in the pneumatised cells of the mastoid process due to mastoiditis in archaeological skeletal remains, based on macroscopic, endoscopic, light and scanning‐electron microscopic investigations. For the purposes of this study, we used an early medieval Frankish population from Dirmstein, State of Rhineland‐Palatinate, Germany. Copyright © 2008 John Wiley & Sons, Ltd. 相似文献
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Barma Grande 2, a male skeleton of upper palaeolithic age from Balzi Rossi (Liguria, Italy), shows a marked degree of upper limb bilateral asymmetry. Similar cases of asymmetry in palaeolithic hominid fossils have variously been attributed to high levels of behavioural asymmetry (related to handedness) or a pathologically induced alteration of upper limb skeletal remodelling processes. As in many of these cases, the skeleton from Barma Grande lacks any indications of trauma or pathology in the smaller left limb. Consideration of the morphology of the preserved upper limb elements and a comparative analysis of asymmetry in normal and pathological male palaeolithic fossils and normal recent human samples suggests that the asymmetry in Barma Grande 2 was a secondary effect of trauma or pathology in the left side. The degree and pattern of asymmetry in numerous humeral and ulnar measurements indicates an adult onset of altered loading patterns. Several possible aetiological factors are considered, with the most probable being an entrapment neuropathy, direct trauma to one or more muscles about the shoulder, or possibly glenohumeral joint instability. © 1997 by John Wiley & Sons, Ltd. 相似文献
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Despite an observable increase in the number of studies using ancient DNA analysis to diagnose disease in human remains, there remain issues to be addressed about the quality of the resulting publications. This paper describes the qualitative analysis of published papers that describe the detection of pathogenic DNA in human skeletal and mummified remains from archaeological sites. Its ultimate goal is to provide an overview of the main problematic issues in relationship to standards developed in molecular biology and to make recommendations for future work. Sixty‐five papers published between 1993 and 2006 were surveyed and the quality of each was assessed using 15 criteria. Interesting results emerged. Of particular note was the high number of papers that did not acknowledge the use of even basic contamination control (90%) or procedures to validate results independently (85%). This study illustrates that attention to contamination control and authentication of results is needed in future research, if confidence in aDNA analysis in palaeopathology is to be increased. Additionally, methods of analysis must be described in published papers to ensure transparency in processes utilised to generate the data. Copyright © 2008 John Wiley & Sons, Ltd. 相似文献