The Golgi Stain: Invention,Diffusion and Impact on Neurosciences

The black reaction, invented in 1873 by Camillo Golgi (1843-1926), was the first technique to reveal neurons in their entirety, i.e. with all their processes. This important development passed unnoticed at first and only received wide international attention after a long delay. The Golgi stain was widely employed for almost thirty years and was directly responsible for major advances in our knowledge of the microscopic anatomy of the nervous system, as well as in other fields of study. In the hands of other researchers, the black reaction provided vital evidence that helped to establish the neuron theory. The Golgi stain was almost forgotten in the period between the two World Wars, but the introduction of the electron microscope to neurocytological research revived its use around the middle of the twentieth century. Today, the black reaction is still used extensively not only in combination with electron microscopy, but also as an autonomous technique in studies on the evolution, ontogeny, and organization of the nervous system.     

The original spaciality of the body itself: phenomenology and neurosciences

The phenomenological tradition stands opposed to contemporary cognitive science in this, that so far from being a mere thing in the physical world, a thing whose mind would contain some mental representation, the lived body is constituted in its sense of being for the subject by being used and actively appropriated by this self-same subject, as agent. Though not already generally acknowledged, there are important similarities between this conception and one, which emerges from the literature of brain cartography over the last twenty years, that of a functional morphogenetic neurodynamics, induced and modulated by experience in a relatively autonomous way, in relation both to the anatomic structures of the body, as well as the cytoarchitectonic frontiers of brain tissue. Taking advantage of the latter similarities, neuroscientific data can be employed to confirm the Husserlian theory of constitution against the attempts on the part of cognitive science to discredit it, and this whether we are talking about its later modification at the hands of Merleau-Ponty or the original version, which is that of a subjective (transcendental) auto-constitution of the lived body on the basis of the practico-kinaesthetic experience of .     

Status,scale and secret ingredients: the retrospective invention of London porter

Porter, a dark style of beer that was the staple of London in the eighteenth and nineteenth centuries, is conventionally addressed as a discrete invention, suited to large‐scale production, whose appearance led rapidly to enclosure of the trade by a few industrial‐scale producers. This paper by contrast presents the capitalist industrialization of brewing as co‐extensive with, and reinforced by, the long‐term emergence of a consensus definition of porter; the invention story is a retrospective construct that telescopes a century or more of technical change. Balancing established economic accounts, I address the role of product identity as a rhetorical device. London’s greatest brewers were in part assisted in capturing smaller competitors’ trade by the enshrining of large‐scale production as a ‘secret ingredient’ in its own right, essential to the nature of the ‘true’ product.     

The origins of democratic thinking: The invention of politics in classical Athens

While many (perhaps most) of those engaged in the study of philosophy would accept the continued reality and importance of an analytic/continental divide in the discipline, there has been no serious examination of the political dimensions of this rift. Here a series of political assumptions are revealed to be widely held among the British analytic philosophers who were active during the period in which the analytic/continental divide was being established. This paper will approach demonstrating the analysts’ beliefs about the political affiliations of continental philosophy in three ways. Firstly, it will produce direct evidence of the analysts’ belief in the relationship between 19th century continental philosophy and various politically undesirable regimes. Secondly, it will examine in detail one illustrative example, that of Hegel. Thirdly, it will illustrate how the political beliefs already canvassed permeated beyond the limited political critique of continental philosophy into the analysts’ writing on the history of philosophy.     

Bulgarian passports, Macedonian identity: The invention of EU citizenship in the Republic of Macedonia

In this article, I examine some of the social effects that Bulgaria's EU membership has for Macedonia and the meanings that identification documents have for ethnic Macedonians who instrumentalize Bulgarian claims on their Macedonian identity for their own ends. I argue that the case study of Macedonia helps us view identification documents as objects that neither necessarily fix nationality nor are ineluctable guarantees of belonging to the (Bulgarian) nation-state, and understand state documentation practices as practices that do not always produce determined identities and citizen-subjects.     

Complexity and participation: the path of strategic invention

Abstract

The epistemological basis of the participatory action-research (PAR) methodology in the so-called 'paradigm of complexity' is plagued with misconceptions, imprecision and significant omissions. The appropriate and contextualised translation of concepts from the natural sciences for use in the social sciences is particularly necessary in qualitative-structural and participatory-dialectic methodological trends. This paper focuses on the concepts of 'entropy', 'complexity' and 'strategic action'. Based on a general notion of complexity relating to the consideration of uncertainty, innovation and the contextualisation of systems, performance-related aspects indicative of actions implied by this paradigm may be highlighted. Thus, it is argued that the conceptualisation of operations such as 'acting in order to know' and 'act knowing/know by acting', encompassed in the notion of 'strategic invention', complement and exceed the scope of typical planning operations and even self-planning ('knowing in order to act'). In short, these definitions are coherent with an ecosystemic perspective of social and natural reality, in which it is necessary to contextualise what is more or less complex in the world, in our knowledge of the world and in our practical actions when acting in the world. Consequently, participatory action-research methodologies should adopt this complex ecosystemic epistemological perspective, and be designed through a 'strategic invention' approach, in order to clarify the concepts imported from other scientific disciplines.     

Innovation,diffusion, and culture contact: The holocene archaeology of Ghana

Stressing recent research, this review of Ghana archaeology highlights what we know of the advent of sedentism, agriculture, iron technology, and urbanism in Ghana and examines how certain patterns in Ghanaian prehistory depart from the expectations of the progressive evolutionary model that has framed our understanding of world prehistory. It is also argued that the archaeology of Ghana has much to contribute to current debates on the relationship between material culture and identity, and the impact of the Atlantic economy on non-European peoples, and to our understanding of cultural diversity in the past.     

The origin of the term plasticity in the neurosciences: Ernesto Lugaro and chemical synaptic transmission

The Italian psychiatrist Ernesto Lugaro can be regarded as responsible for introducing the term plasticity into the neurosciences as early as 1906. By this term he meant that throughout life the anatomo-functional relations between neurons can change in an adaptive fashion to enable psychic maturation, learning, and even functional recovery after brain damage. Lugaro's concept of plasticity was strongly inspired by a neural hypothesis of learning and memory put forward in 1893 by his teacher Eugenio Tanzi. Tanzi postulated that practice and experience promote neuronal growth and shorten the minute spatial gaps between functionally associated neurons, thus facilitating their interactions. In addition to discovering the cerebellar cells known by his name and advancing profound speculations about the functions of the glia, Lugaro lucidly foresaw the chemical nature of synaptic transmission in the central nervous system, and was the first to propose the usage of the terms "nervous conduction" and "nervous transmission" in their currently accepted meaning.     

Golgi,Cajal and the Neuron Doctrine

Camillo Golgi and Santiago Ramón y Cajal shared the Nobel Prize in 1906 for their work on the histology of the nerve cell, but both held diametrically opposed views about the Neuron Doctrine which emphasizes the structural, functional and developmental singularity of the nerve cell. Golgi's reticularist views remained entrenched and his work on the nervous system did not venture greatly into new territories after its original flowering, which had greater impact than is now commonly credited. Cajal, by contrast, by the time he was awarded the Nobel Prize, was already breaking new ground with a new staining technique in the field of peripheral nerve regeneration, seeing the reconstruction of a severed nerve by sprouting from the proximal stump as another manifestation of the Neuron Doctrine. Paradoxically, identical studies were going on simultaneously in Golgi's laboratory in the hands of Aldo Perroncito, but the findings did not seem to influence Golgi's thinking on the Neuron Doctrine.     

Neurobiographies: writing lives in the history of neurology and the neurosciences

This essay surveys the present state of biographical writing in the history of neurology and neuroscience. Individual lives play a significant role in practitioner-historians' narratives, whereas academic historians tend to be more nonindividualistic and a-biographical. Autobiographies by neurologists and neuroscientists, and particularly autobiographical collections, are problematic as an historical genre. Neurobiographies proper are published with several aims in mind: some are written as literary entertainment, others as contributions to a cultural and social history of the neurosciences. Eulogy, panegyrics and commemoration play a great role in neurobiographical writing. Some biographies, finally, are written to provide role-models for young neuroscientists, thus reviving the classical, Plutarchian biographical tradition. Finally, a recent cooperative biography of Charcot is mentioned as an example of how the biographical genre can help overcome the alleged dichotomy between the historiographies of practitioner-historians and academic historians.     

Artifacts of the neurosciences: A resource guide to museums and collections

ABSTRACT

Medical museums and collections care for important artifacts relating to the history of the neurosciences across the United States, the United Kingdom, and Europe. This essay highlights the collections and galleries of greatest interest and worth a visit. It also provides a list of online directories of medical museums and bibliography of related publications.     

The invention and uses of folk art in Germany: wooden toys from the Erzgebirge mountains

This article attempts to historicise the concept of “folk art” using the example of wooden toys from the Erzgebirge mountains to show that it was invented by cultural élites as a marketing concept at the beginning of the twentieth century in order to support a domestic industy caught in structural crisis.     

Language as apparatus: entanglements of language,culture and territory and the invention of nation and ethnicity

Postcolonial linguistics has shown that African languages emerged from a complex figuration of missionary, scientific and colonial practices. The article interprets this emergence as the result of an existential onto-epistemological dislocation stabilised through the hegemonic project of colonialism. It rests on an apparatus of modernity that separated nature and culture/society and stabilised this new order with a particular notion of language as an autonomous object. In the nineteenth century, language enters a conjunction of territory and culture, which played out in Europe in the terms of a nationalist, hegemonic trajectory and in Africa as the fractionation of ethnic/linguistic groups and the pervasive linguo-ethnification of contemporary societies. Thus, language can be understood to be an apparatus productive of nationalism as well as ethnicity. In an attempt to demonstrate the plausibility of this conceptualisation, I show how today these trajectories have effects in that Afrikaans in South Africa as ethnified language loses and Swahili in Tanzania as national language gains ground at the respective universities. Both languages compete with global academic English, which despite its colonial heritage appears as a deterritorialised, culturally neutral language.     

The international monetary system: diffusion and ambiguity

This article examines the dynamics of power and rule‐setting in the international monetary system. It begins with a brief discussion of the meaning of power in international monetary relations, distinguishing between two critical dimensions of monetary power: autonomy and influence. Major developments have led to a greater diffusion of power in monetary affairs, both among states and between states and societal actors. But the diffusion of power has mainly been in the dimension of autonomy, rather than influence, meaning that leadership in the system has been dispersed rather than relocated—a pattern of change in the geopolitics of finance that might be called leaierless diffusion. The pattern of leaderless diffusion, in turn, is generating greater ambiguity in prevailing governance structures. Rule‐setting in monetary relations increasingly relies not on negotiations among a few powerful states but, rather, on the evolution of custom and usage among growing numbers of autonomous agents. Impacts on governance structures can be seen on two levels: the individual state and the global system. At the state level, the dispersion of power compels governments to rethink their commitment to national monetary sovereignty. At the systemic level, it compounds the difficulties of bargaining on monetary issues. More and more, formal rules are being superseded by informal norms that emerge, like common law, not from legislation or statutes but from everyday conduct and social convention.     

“Reckless,cavalier, dismissive,petty and vengeful”?: The impact of municipal constituency change on candidate diversity

The demographic composition of electoral districts has an important influence on the identities of candidates because they affect the political opportunity structures of ethnic minorities and other marginalized groups. The 2018 municipal election in Toronto, Canada provides a unique opportunity to examine how changes to electoral districts impacted the participation of visible minority candidates. At the end of the initial nomination period, the right-wing populist provincial government of Doug Ford reduced the number of city council wards from 47 to 25, which also affected the boundaries of school board districts. Candidates and aspirants then had the opportunity to re-register in the new constituencies. This change constitutes a natural experiment that allows us to isolate the impact of district structure on the relationship between demographics and candidate ethnicity. Using logistic and Poisson regression modeling, we compare the proportion and number of Visible Minority and White candidates before and after consolidation. Contra expectations, we did not find any effect on minority candidates, but show some evidence that consolidation reduced opportunities for Whites. We trace this unexpected finding to the geographic patterns of ethnic settlement.