Schistosomiasis A persistent parasitic disease

Abstract

Some of the more fascinating aspects of schistosomiasis biology that make this parasitic disease such a formidable challenge to control are explored. For instance, major environmental change can lead to outbreaks of disease. Research work applying genome analysis to schistosomiasis is described and improved knowledge of the molecular composition of the parasite should lead to the discovery of new targets for control strategies. The review demonstrates that research in tropical diseases requires an interdisciplinary input from diverse scientific professions.     

Reflections on Cardiovascular Diseases

Abstract

Cardiovascular diseases increase with the age of the individual and as the world's population will have an increasing number of aged members by the year 2000, these diseases deserve special attention. The present state of our knowledge is reviewed, and the author concludes that there is only a single motto for the future: Prevention.     

Embedding entrepreneurial regional innovation ecosystems: reflecting on the role of effectual entrepreneurial discovery processes

ABSTRACT

Collaboration between regional stakeholders is increasingly emphasized in innovation policy as a way to activate the inherent agency in a regional innovation system. Partnerships of diverse stakeholders have been identified as critical, being able to envisage and implement future pathways that in turn bring change to a region. Thus, the knowledge of various stakeholders is supposed to be combined in novel ways in order to define regional assets and possible future pathways. Nevertheless, it has been recognized that these agency activation approaches often fail to realize these long-term visions initially agreed by partners. We here draw on Sotarauta’s notion of policy ‘black holes’, where regional partners repeat past superficial successes rather than driving in to systemic change. We seek to understand the conditions under which regional stakeholders can build realistic and adaptable strategies that shift regional development trajectories. We explore this via a qualitative approach comparing entrepreneurial discovery processes in three peripheral regions, namely Twente (Netherlands), Aveiro (Portugal) and Lincolnshire (UK). We reflect on the potential value of more effectual (opportunistic/ flexible) approaches to entrepreneurial discovery. We argue that black hole problems may arise from the way agency activation strategies conceptualize long-term strategy development, if partners’ mind-sets are too causal and lacking flexibility to continually reorient strategies during implementation better towards these collective visions.     

Saving the Rose Theatre: England's first managed and monitored reburial

Abstract

The discovery of the Elizabethan Rose Theatre in London in 1989 led to pressure on the government for the site to be preserved for future full excavation and the display of the remains in situ. This paper describes briefly the historical and geological background to the theatre site, and discusses the rationale of the burial system adopted and the methods used to monitor the condition of the site. The burial system was designed with a limited life expectancy of a few years and it was, and still remains, the objective of the Rose Theatre Trust to raise sufficient money for the theatre to be displayed. However, fourteen years on, the system continues to perform satisfactorily. The methodology is reviewed, particularly the use of expensive and scarce Buckland sand, and finally, the options for the future of the theatre's remains are considered.     

The re-identification of great bustard (Otis tarda) from Fishbourne Roman Palace,Chichester, West Sussex,as common crane (Grus grus)

Abstract

This paper details the results of recent reanalysis of the animal remains from the 1960s excavations at Fishbourne Roman Palace, West Sussex. It argues that specimens originally identified as belonging to the great bustard are, in fact, misidentified remains of common crane. This discovery has important connotations. First, these findings need to be reported so that the avian archaeological record can be updated to avoid future syntheses of Romano-British faunal remains incorrectly including great bustard. Secondly, interpretations of the zooarchaeological remains at Fishbourne Palace will alter, due to the differing ecological histories of bustards and cranes.     

Our Heritage – Our Future

Abstract

Much of our present technology can be traced to the great discoveries at the beginning of our century, particularly relativity and quantum mechanics. This is our heritage. Based on these, reasonable extrapolations can be made for our future, and are here exemplified by microelectronics, lasers, molecular biology, new material, aviation and nuclear energy. But often the unexpected development is the most important, here compared with non-linear equations in mathematics. Man's great future will arise from such non-linearities and the space telescope may bring a new field theory, redundancy in computers may give us thinking machines and finally the discovery – or the proof of absence – of extra-terrestrial life will bring the greatest of all non-linear changes. It is concluded that human imagination is unlimited, that imagination lets man grow to transcend his limits and to fulfil his dreams.     

Technology,Free Labor,and Slavery: Lincoln on Discovery and Invention

Abstract

Abraham Lincoln presented a lecture in 1858–1859 on the process of “Discoveries and Invention.” In this lecture he discusses man's desire to improve his condition and the use of technology to that end. The process of discovery and invention allows man to develop that technology and alleviate his state. Education, especially literacy, allows knowledge to be passed down through time, facilitating yet further improvement. Yet, Lincoln warns that human nature can also become raw material, as seen in the institution of slavery. In light of Lincoln's more commonly known natural rights argument against slavery, this warning about human nature takes on greater significance. Coupled with an address on agriculture from 1859, Lincoln's lecture on discovery and invention attempts to illustrate the liberating power of invention and education while reminding us of the limits posed by man's natural equality.     

South American Palm Seeds (Orbignya sp.) in Dutch Shipwrecks

Abstract

In this note we report the discovery of some palm seeds (Orbignya sp.) from three shipwrecks in the Netherlands. They all date from the second half of the 17th century. Some palm seeds, published as Attalea funifera, were already known from the Dutch coast.     

Digging for the Dead: Archaeological Practice as Mortuary Commemoration

Abstract

Archaeologists have yet to fully appreciate the complex interactions between archaeological practice and contemporary responses towards death and commemoration in the UK. The paper reflects upon the experience of working with the local community during archaeological fieldwork in and around an English country churchyard at Stokenham in the South Hams district of Devon in southwest England during 2005 and 2006. Using this case study, it is argued that the current theories and parameters of both mortuary archaeology and public archaeology fail to adequately engage with the diverse community perceptions and concerns over mortality and commemoration. At Stokenham, the archaeological research and student-training programme engaged local people in the discovery of their past but (more importantly for the local community) also helped to secure an acceptable commemorative future. It is argued that this provides a case study of how archaeological practice can interact with community attitudes to death and memory.     

POTTERY VESSELS FROM A NEWLY DISCOVERED AMMONITE DOVECOTE AT AIN AL-BAIDA,AMMAN

Abstract

This paper deals with pottery vessels from a newly discovered Ammonite dovecote located at Ain al-Baida in north-east Amman. This dovecote may have operated independently or as an adjunct to a large estate or farm holding. Based on parallel ceramic studies, the writers date the establishment to the period from the late eighth to the sixth centuries BC. This discovery is unique, since no other comparable example from the late Iron Age is attested in Jordan.     

The Rose Theatre: Twenty Years of Continuous Monitoring,Lessons, and Legacy

Abstract

The discovery of the Rose Theatre in 1989 led to the implementation of new planning guidance focused on the presumption that the preferred response to development impacting on archaeological sites would be mitigation and preservation in situ. There was little understanding of what the impact of mitigation would be on the quality of the buried evidence and the Rose Theatre site was the first to be scientifically monitored. As a direct result research was implemented and the PARIS series of conferences were initiated.     

Sputniks,explorers and propaganda: The discovery of the earth's radiation belts 1

Abstract

The most important scientific discovery of the early space era ‐ the 1958 discovery of the radiation belts of the Earth ‐ was made in the context of Cold War rivalry between the USSR and the USA. The paper uses previously unavailable archival records to reconstruct the relative contributions of American and Soviet researchers and their interations during the process of discovery. The former discovered what is now known as the inner radiation belt, while the latter observed the outer radiation belt and gradually came to realize the existence of two distinctively different zones of radiation. The uses of science for the purposes of Cold War political propaganda affected the behavior of scientists and led to the misrepresentation of the events in mass media.     

Auroral Research and the Character of Astronomy in Enlightenment Sweden

Abstract

The observation of the magnetic effects of the aurora borealis by Olof Hiorter in the 1740s was hailed by Swedish scientists as one of the major discoveries in contemporary research. This article investigates the political and academic context of the discovery, focusing on the astronomical ideals promoted by Hiorter. He used the discovery in order to buttress the importance of his own scientific character – technically competent, hard-working and research-oriented. He contrasted this ideal with the character of an ordinary university professor who was described as more of a bureaucrat, interested in science only as long as it could boost his reputation, and not averse from stealing results of technically more competent underlings. Hiorter's opponents at the university decried his lack of theory and devalued the importance of technical skill. This conflict is discussed in the context of ideals concerning cultural, political and economic values of science and scientists.     

A Gothia in the Hellespont in the early eighth century

Abstract

Alexander Kazhdan has recently brought to light a fascinating passage in the Commentary on Gregory of Nazianzos' Poems by Cosmas of Jerusalam, an obscure and little read text. While my interpretation of the passage differs from the one proposed by Prof. Kazhdan, the credit for its discovery belongs entirely to him.     

War on the Mind

Abstract

The new biology, a formidable triad of the disciplines of biochemistry, genetics and cell biology, has given an entirely new insight into disease processes. It is forcefully argued here that this interdisciplinary approach should be applied to tropical diseases. The detailed strategy and possible engineering of a malaria vaccine, as developed at the author's Institute, are cited as an example. But finally, society must decide if the new biology is to be used for research on the diseases of the rich or the poor peoples of this planet.     

Early ironworking in Iron Age South India: New evidence for the social organization of production from northern Karnataka

Abstract

Iron production was integral to political and ritual practices during the South Indian Iron Age (ca. 1200–300 b.c.), yet the investigation of the social relations of metals production during this period has been overshadowed by studies of iron consumption, particularly of iron objects in megalithic mortuary contexts. Recent archaeological research in the Tungabhadra River Corridor, Karnataka, has revealed iron production debris within and between settlements in more ephemeral occupational contexts, such as rockshelters. One notable discovery is the earliest ironworking facility in South India at Bukkasagara. The regional pattern suggests that iron production involved at least two classes of specialist producers—smelters and smiths—who exercised varying degrees of control over the practice and products of their craft. It also suggests that iron production was an important component in the construction and negotiation of Iron Age social differences, affiliations, and inequalities.     

Balancing Archaeological Responsibilities and Community Commitments: A Case from Honduras

Abstract

Exploring the implications of a recent discovery in NW Honduras, this paper considers the ethical dilemma that arises when an archaeologist's responsibility to disseminate information conflicts with her/his commitment to protect cultural resources. We suggest that applied archaeology that benefits local communities among which investigations are conducted is a first step toward developing long-term solutions to conservation and stewardship challenges.     

La Découverte de L’Amérique

This article examines the significance accorded to the discovery of America in the period between 1492 and the publication of Alexander von Humboldt’s Kosmos in 1855. It argues that, the « discovery » of America was perceived as the « uncovering » of not merely a place, but of an epistemological challenge which both transformed, Europe’s intellectual dependence on Antiquity, and shaped its evolving perception of both space and time. It argues that, after the discovery, human history came to be seen, in terms of as series of inventions all of them related to human movement, which were projected, as more and more of the globe was « discovered » into an unpredictable future.