Commercializing Science in Europe: The Cambridge Biotechnology Cluster

The article examines the variety of linkages firms have established with university science. These include using universities as a source of ideas for start-ups, scientific collaboration between firms and laboratories, the role of scientists on the scientific advisory boards of firms, and the role of universities in supplying firms with a labour market for talented scientists. These linkages are plentiful across Cambridge area biotechnology firms. However, and perhaps surprisingly, our evidence shows that a key actor, the University of Cambridge does not dominate the scientific linkages of the area's firms. A large percentage of Cambridge's firms do not derive from its university. The majority of scientific collaborations are not with University of Cambridge laboratories, nor do Cambridge scientists dominate the scientific advisory boards of firms. Moreover, the majority of scientists within area biotechnology firms appear not to have left University of Cambridge laboratories to move to industry.     

A Generalized Randomization Approach to Local Measures of Spatial Association

This article establishes a unified randomization significance testing framework upon which various local measures of spatial association are commonly predicated. The generalized randomization approach presented is composed of two testing procedures, the extended Mantel test and the generalized vector randomization test. These two procedures employ different randomization assumptions, namely total and conditional randomization, according to the way in which they incorporate local measures. By properly specifying necessary matrices and vectors for a particular local measure of spatial association under a particular randomization assumption, the generalized randomization approach as a whole yields a reliable set of equations for expected values and variances, which then is confirmed by a Monte Carlo simulation utilizing random permutations.     

Fortune Favours the Prepared Region: The Case of Entrepreneurship and the Capitol Region Biotechnology Cluster

The US Capitol region ranks as one of the important biotech clusters in the US. This article documents the general dimensions of the innovative milieu and highlights the historical development of the cluster. The Capitol region biotechnology cluster, in essence, is the result of three reinforcing sets of factors: pre-existing resources, entrepreneurship and the incentives and infrastructure provided by government. Due to significant investments in science and technology the region was prepared to capitalize on technological opportunities in biotechnology as well as institutional policy changes that facilitated technology-based entrepreneurship.     

Knowledge Management Approach to Performance: a United Arab Emirates Experience

Knowledge management is gaining prominence in academia and practice. The need for organizations in the United Arab Emirates (UAE) to empower themselves through knowledge management cannot be ignored. Yet, not much empirical evidence on the subject can be found in the literature. This study investigates the effect of the following factors: organizational culture, organizational infrastructure, technical infrastructure, management support, reward and vision clarity on organizational performance in terms of efficiency, customer satisfaction, decision‐making, quality of work, and financial benefits. A questionnaire was used to collect data from general managers, functional managers, IT managers and chief knowledge officers from a variety of business companies from private and public sector drawn from Dubai Financial Market website. Data was analyzed using the Statistical Package for Social Sciences (SPSS). Results show that all investigated knowledge management dimensions are implemented in UAE organizations subject of this study. They are also significantly correlated with performance improvement except reward.     

Multi-level Science Policy and Regional Innovation: The Case of the Munich Cluster for Pharmaceutical Biotechnology

Knowledge-based industries tend to develop within regional or local clusters that allow for knowledge spillovers, the generation of a critical mass of complementary competencies and skills as for spatial proximity to academic organizations out of which many highly innovative firms have been founded. The prototype of that development certainly is the biotechnology industry which has emerged since the 1970s first in the US where especially small and medium-sized research companies have been established around leading science bases. Following the example of the US biotechnology industry, public policies in many industrialized countries aimed at stimulating cluster formation in biotechnology. This holds true especially for member states of the European Union (EU) where public policy initiatives have been initiated at different territorial levels. This article refers to the Munich pharmaceutical biotechnology cluster and applies institutional and organizational indicators that have been developed in various systemic analyses of technological development and innovation. It will be shown that reforms of the institutional environment in which the innovative organizations are embedded were crucial for the commercialization of biotechnological research in Germany. These reforms have occurred mostly at the regional and national level, whereas the EU played a role especially in establishing the regulatory framework for the biotechnology industry. Organizational indicators will be applied in order to assess the modes of knowledge production within the cluster.     

Informality and Flexible Specialization: Apprenticeships and Knowledge Spillovers in an Indian Silk Weaving Cluster

This article draws on quantitative and qualitative data from the Banaras (Varanasi) silk weaving cluster in North India to show how informal institutions based on family and community interact with the relations of production to enable flexible specialization while reproducing or accentuating inequality. The family‐based apprenticeship system produces a supply of highly skilled workers but contributes to labour surplus by lowering the costs of entry and making exit difficult. Surplus labour ensures that productivity gains resulting from technical improvements do not accrue to weavers as higher wages. A community of artisans called the naqsheband (designers) produces fabric patterns that are central to the industry's market. Geographical clustering results in quick diffusion of these designs and free imitation is the key to innovation. But this entails hyper‐competition, conservative changes, a culture of secrecy and quickly dissipating monopoly rents. The Banaras case enables us to understand how collective efficiencies as well as inefficiencies are created by the same institutions.     

Across the narrow sea: A Transnational Approach to Anglo-Dutch Travelogues

ABSTRACT

The busy traffic between England and the United Provinces in the seventeenth century produced travel literature by merchants, scholars, soldiers, and diplomats. What can these sources tell us about commonalities and differences among these travellers and between the nations?

This article provides a case study of a transnational approach, setting Dutch and English accounts side by side to enrich our understanding of how travellers sought out specific sites and institutions.

Strikingly, travellers reported on similar themes, such as royalty, universities and war, yet were also keen to draw contrasts with the visited country.

We show how these patterns of travel and imagery can throw light on Anglo-Dutch relations, providing us with the personal nuance often absent from official texts. Simultaneously, Anglo-Dutch relations affected the destinations and outlooks of travellers. The contribution of this article is its presentation of new material in an Anglo-Dutch framework.     

Maritime Cultural Landscape: A New Approach to the Cascais Coastline

Portuguese Archaeology only recently began to address the concept of maritime cultural landscape. In this article we intend to analyze the impact that this kind of approach has upon the study of a littoral characterized by a cliffed coast and a seafloor that is morphologically complicated by the estuary influences of the Atlantic Ocean and the Tagus River. The coast of Cascais, located near Lisbon, is the space that we wish to address with this epistemological paradigm. A large spectrum of sites composed of fortresses, lighthouses, harbors, anchorages, and shipwrecks permits a longue durée examination. The relationships and networks between humans and archaeological remains, directly and indirectly linked to the nautical past, are observed diachronically with a focus on the early Modern Period.     

"文革史学"初探--以中国近代史研究为例

“文革史学”是指1966-1976年“文化大革命”期间中国“史学”的发展和演变的历史,它既是中国史学史、也是“文革”研究的重要组成部分。“文革史学”是动乱年代政治运动的特殊产物,是中国史学史上极为黑暗的一页,给中国史学蒙上了极大耻辱。它截断了中国史学的优良传统,并离群索居,与不断前进的世界史学背道而驰;中国史学成了政治史学、影射史学的代名词,失去了作为一门科学的独立性与尊严。     

Innovating in Cluster/Cluster as Innovation: The Case of the Biotechvalley Cluster Initiative

It has been noted that innovation seems to take place to a higher degree in clusters than elsewhere and we have lately seen a worldwide wave of emerging cluster initiatives and similar innovation policy projects. Some of these are realistic efforts based on existing regional strengths and partly existing cluster structures. Most, however, are grasping at straws. The latter is especially true when it comes to technologies such as IT and biotech. We could subsequently add a new label—“pathetic clusters”—to the already existing list of embryonic, emerging, world-class or stagnating clusters. But what do we make of such “pathetic clusters” (are they really pathetic)? Although economic geographers often tend to explain innovation (competitiveness) by looking at cluster dynamics, in such accounts, the cluster concept itself can actually function as an innovation, imposing similar effects on the economy as more familiar types of innovation would, i.e. by creating a local competitive edge. It is reasonable to believe that if “pathetic clusters” play important roles in regional economies, then they do so in the form of social and organizational innovations rather than as Porterian drivers of innovation and industrial dynamics on a large scale. This function of the cluster concept—as a local innovation—is the focus of the paper at hand.     

度量关系的新方法:考古学中的网络分析

考古学中的网络分析以节点和链接为底层架构,强调以联系的视角去看待事物本身及其发展过程,探究此种联系是如何对古代社会的进程产生影响的.两个学术传统的交织塑造了当前网络分析在考古学中的面貌:社会网络分析(Social network analysis)和复杂性科学(Complexity science).其研究思路分为两种...     

The Geography of Knowledge Transfer and Innovation in Biotechnology: The Cases of Scotland,Sweden and Denmark1

This paper addresses themes at the heart of policy debates on innovation systems and concentrates on the process of progressive transformation that has been affecting the therapeutic and diagnostic sectors as a result of the application of molecular biology. The focus is on the relationship between firms' locational choices, innovation policy and industrial dynamics. The issue of knowledge transfer is explored and the discussion addresses the theoretical controversy between two contrasting approaches: while some describe open networks and collaboration as means of enhancing competences for learning, others argue that, as intellectual assets are protected by property rights, knowledge adheres to specific locations mainly as a consequence of scientists' immobility. Then it is assessed whether knowledge transfer, in its different forms, is prevalently local or tends to occur on a global scale. Finally, the perceived effectiveness of some policy measures directed to enhance connectivity among players holding complementary knowledges is examined. Countries such as Sweden, Denmark and Scotland, who have pioneered the implementation of cluster thinking in Europe, provides an ideal setting to conduct this empirical study.     

Experimentation in the Formation of Edge Damage: A New Approach to Lithic Analysis

Abstract

The paper describes a series of experiments recently carried out to test the formation of edge-damage on flaked stone tools which results from their being used in various tasks. Variables that were systematically tested include action, worked material, angle of the edge, and grip. The main criterion in distinguishing different patterns of damage was microflaking rather than abrasion in the form of striations and polish.

The results of these experiments may be applied to the identification of patterns of damage to the edges of prehistoric stone tools. The information gained from such microwear analysis may be used not only to provide details on the activities and settlement organization of prehistoric societies, but also to provide an important new dimension to lithic analysis in general. In lithic analysis, the main criteria of change have been the macromorphological features of the tools. It is our contention, however, that the additional information on the function of the tools, which is provided by microwear analysis, can contribute to the greater understanding of the processes of change in lithic assemblages and culture change as a whole.

The experimental program was designed to test the formation of edge-damage on implements manufactured in European chalk flint. It was to aid in the identification of wear patterns on lithic assemblages from the neolithic period in Central and Eastern Europe, a project in which the authors were involved. Its relevance, however, includes directly those assemblages of the post-Pleistocene period in temperate and Mediterranean Europe. The results of the experiments may also be useful, it is hoped, for lithic analysis in general, both in the Old and New World.     

Ancient Egypt in Brazil: A Theoretical Approach to Contemporary Uses of the Past

In this paper we consider archaeology as a product of social interaction, and discuss how ancient Egyptian materiality has been an important part of identity building in Brazil. We begin by reviewing our theoretical setting, and suggest that a postmodern approach is most helpful to our goal of understanding the social context of the public uses of archaeology. The paper then turns to the trajectory of “Egyptomania” in Brazil, from the 19th century onwards, highlighting the importance of cultural movements such as Kardecism and Masonry in this trend. We argue that the use of Egyptian subjects in Brazil has connections with social inequality, racism, and gender biases. Finally, we present a case study on positive recent trends in the presentation of ancient Egypt in school textbooks which highlights critical approaches to the use of ancient Egyptian subjects in contemporary Brazil.     

鹿邑微子墓补证——兼释相侯与子口寻(腯)

鹿邑县太清宫镇即春秋相邑。微子即西周金文之相侯。鹿邑大墓铜器铭文中的子口寻,即微子启之孙脯。长字象拄杖形是商周文字,不应用经过讹变的战国楚简中的长字予以否定。