Origins of the Creutzfeldt and Jakob concept

A review of the publications of Hans Creutzfeldt and Alfons Jakob pertaining to the concept which bears their name (CJD) reveals that they described a neuropathological syndrome and were opposed to its classification as a neurological disease. The evidence on which Creutzfeldt and Jakob based their view is reevaluated, and studies by other workers are cited in which a range of environmental and genetic factors generated the CJ syndrome, challenging the proposition that CJD is a disease with a single cause.     

The social representation and reality of BSE's impact in North Central Alberta

Bovine Spongiform Encephalopathy (BSE), popularly known as ‘Mad Cow’ disease, was discovered in the late 1980s in Britain; in 1996, scientists announced a ‘probable’ link between eating BSE‐contaminated meat and a new form of Creutzfeldt‐Jakob disease, a fatal human brain disease. Britain's beef industry was devastated, beef consumption dropped, export markets closed and a mass cull of older cattle was implemented. This article uses social representation theory to analyze how Canada's 2003 BSE outbreak was portrayed to Canadians in major newspapers and compares this representation with BSE's impact in two rural Alberta counties. The day Canada's BSE case was reported, the United States closed its border to Canadian cattle and beef. The event was represented as ‘devastating’ to Canada's cattle and beef industries and rural areas in general, a view that went largely unchallenged and was critical to gaining government support for the affected industries. Little evidence of economic devastation was found in the heart of Alberta's cow‐calf producing area; producers adapted to their changing economic circumstances and acquired other sources of income. But there is little doubt that the financial uncertainty associated with BSE added to stress levels among farm families.     

Devotion to St James and family identity: the Thurns of Salzburg

Miles or knight referred in twelfth-century Salzburg to a servile retainer of a ministerial or noble. In the thirteenth century the knights coalesced with the lesser ministerials, who were the vassals of the great ministerial lineages, to form the estate of knights, the lowest strata of the Salzburg nobility. The Thurns are an example of lesser ministerials who belonged to the estate of knights and who rose to prominence in the thirteenth century by serving the archbishops of Salzburg. The founder of the lineage's fortunes was Werner I of Lengfelden (1230–1268), the master of the archbishop's kitchen, who built St Jakob am Thurn, south of Salzburg. The distinguishing characteristic of the lineage was its devotion to the Apostle James, a saint associated with knighthood. The Thurns adopted Jakob as their leading name, built the church of St James next to their tower, St Jakob am Thurn, and the church of St James in Faistenau, and were buried in the chapel of St James in Salzburg, which they endowed.     

A Patient With Word Blindness in the Seventeenth Century

Johann Jakob Wepfer (1620–1695), city physician in Schaffhausen, Switzerland, published two books on “apoplexy.” He proposed new ideas about the events in the brain during such attacks, based on Harvey’s theory of the circulation of the blood. Wepfer postulated extravasation of whole blood or serum in the brain, in opposition to the Galenic notion of blocked ventricles. His case histories are remarkably precise and untainted by interpretation. This allows the recognition of a patient with word blindness, who was also unable to read words written by himself. Unlike patients with pure “alexia without agraphia,” he could not write complete sentences because of additional language defects, especially speech comprehension. Jules Dejerine (1849–1917) would, in 1892, not only describe a patient with the pure form of this syndrome (cécité verbale avec intégrité de l’écriture spontanée et sous dictée) but also provide an explanation of its anatomical basis.     

Out of ‘Common Humanity’: Humanitarianism,Compassion and Efforts in Australia to Assist Jewish Refugees in the 1930s

In June 1935, Edith Roll, a thirteen-year-old from Vienna, wrote to her Australian pen-pal, Jean Doig, aged ten. This correspondence was tragically short-lived. Edith Roll’s family was swept up in the murder and destruction of Jews in Europe. The efforts of Jean’s parents – the respected country doctor, Keith Doig, and his wife, Louie – who attempted but failed to assist Edith and her family, her father, Jakob Roll, her mother Emilie and brother Fritz, are examined in this article. To disregard their efforts as tangential to the history of refugees because they were unsuccessful means we miss an opportunity to explore the historically situated notions of compassion and empathy that can be at the centre of these endeavours. Drawing on personal letters rather than the views of government officials, this article examines the Doig family efforts and what inspired them, arguing that these are a vital part of the complex story of refugee and migration history.     

The European miracle. Environment,economies and geopolitics in the history of Europe and Asia

This article analyses the 1936 “Wotan” essay by Swiss psychologist Carl Gustav Jung in light of one of its reigning motifs, Ergriffenheit. First, this term is examined within the works of Protestant theologian Rudolf Otto and Indologist Jakob Wilhelm Hauer, who used it to describe what they claimed to be the original religious experience, a state of being deeply stirred or even seized by the “the holy” or by “the ultimate reality.” The article then examines antecedents in Jung's theory of states of psychic seizure, in which two halves of the psyche come into conflict, the resolution of which leads to an increased capacity to create the arts of culture. The analysis then moves to the “Wotan” essay itself, where Jung brings together his own theory of psychic seizure with the theory of the original religious experience as proposed by the above-named scholars of religion in order to suggest that, under National Socialism, the Germans were in the midst of a collective confrontation with their own inner divinity, which should lead to a national spiritual rebirth. The article then investigates the works of several of the men Jung mentions in the essay, as well as his use of ancient Germanic mythology, to support his claim. Through his portrait of the Germanic archetype Wotan, Jung psychologizes and thereby essentializes the Romantic image of the Germans as “a people of poets and philosophers” as well as that of a Nietzschean “master-race.” In conclusion, the article argues that, at least in 1936, Jung's attitude towards Hitler and National Socialism was much more favorable than has previously been recognized.     

Wotan and the ‘archetypal Ergriffenheit’: Mystical union, national spiritual rebirth and culture-creating capacity in C. G. Jung's ‘Wotan’ essay

This article analyses the 1936 “Wotan” essay by Swiss psychologist Carl Gustav Jung in light of one of its reigning motifs, Ergriffenheit. First, this term is examined within the works of Protestant theologian Rudolf Otto and Indologist Jakob Wilhelm Hauer, who used it to describe what they claimed to be the original religious experience, a state of being deeply stirred or even seized by the “the holy” or by “the ultimate reality.” The article then examines antecedents in Jung's theory of states of psychic seizure, in which two halves of the psyche come into conflict, the resolution of which leads to an increased capacity to create the arts of culture. The analysis then moves to the “Wotan” essay itself, where Jung brings together his own theory of psychic seizure with the theory of the original religious experience as proposed by the above-named scholars of religion in order to suggest that, under National Socialism, the Germans were in the midst of a collective confrontation with their own inner divinity, which should lead to a national spiritual rebirth. The article then investigates the works of several of the men Jung mentions in the essay, as well as his use of ancient Germanic mythology, to support his claim. Through his portrait of the Germanic archetype Wotan, Jung psychologizes and thereby essentializes the Romantic image of the Germans as “a people of poets and philosophers” as well as that of a Nietzschean “master-race.” In conclusion, the article argues that, at least in 1936, Jung's attitude towards Hitler and National Socialism was much more favorable than has previously been recognized.     

Gabrielle Lévy and the Roussy-Lévy syndrome

In 1934, Gabrielle Lévy died at the age of 48. She became well known for an article she published on a hereditary polyneuropathy in cooperation with Gustav Roussy, resulting in the eponym Roussy-Lévy syndrome. Not much is known about this extraordinary neurologist/neuropathologist. Her family declared that she died from the disease she was studying. She was a pupil of Pierre Marie, with whom she worked at the Salpêtrière in Paris and wrote on war neurology. In cooperation with Marie, she published a number of articles on postencephalitic syndromes, which also became the subject of her 1922 thesis. Three years later, she became associate physician at the Paul-Brousse Hospital in Paris, where the study of brain tumors became one of the subjects of her scientific work. Remarkably, Lévy was first author in a few of her many articles, although Roussy confirmed that she often initiated the study and even wrote the main part. In this article her career is considered in the context of the struggle of women physicians to improve their position during the early-twentieth century. She probably died from a brain tumor or a postencephalitic syndrome.     

Copper worlds: a historical archaeology of Abraham and Jakob Momma-Reenstierna and their industrial enterprise in the Torne River Valley,c. 1650–1680

This article analyses the industrial enterprise of the Dutch-born brothers Abraham and Jakob Momma-Reenstierna and their investments in Sápmi and the upper parts of the Torne River Valley, northern Sweden, during the second half of the seventeenth century. The aim is to explore the driving forces behind the industrial projects of the two brothers in a larger global and colonial context. With inspiration from recent critical studies on the simplifications, and Eurocentrism, in earlier understandings of the birth of modernity, we focus on the modernizing processes taking place in the upper part of the Torne River Valley as a meeting zone between local populations and landscapes and external capital. Metal extraction was booming in the seventeenth-century Sámi areas. Both the Danish-Norwegian and the Swedish Crowns invested heavily in the mining of silver, copper and iron. The scientific focus in archaeology and history has hitherto been very much on the state-governed projects, and limited interest has been directed towards the private enterprises. Moreover, there is also a need to study the roles of the local Finnish and Sámi populations, as well as the global connections, in these colonial industrial projects.     

The Poison and the Spider's Web: Diderot and Eighteenth-Century French Epicureanism

This article argues that the term ‘Epicurean’ had multiple meanings in the moral and political thought of the eighteenth century. Concentrating on the reception of Epicureanism in France, it shows that some critics focused on Epicurus’ hedonistic moral psychology and labelled Epicurean those thinkers who denied natural sociability; for others, who instead focused on Epicurus’ materialist natural philosophy, to label a thinker an Epicurean was to label them an atheist. This polyvalence is presented as a salutary caution against essentialising claims about the content of eighteenth-century Epicureanism per se. Despite this sceptical stance, however, the article goes on to argue that it is nevertheless fruitful to investigate the engagement with Epicureanism by particular thinkers or in particular texts. Indeed, a comparative reading of Denis Diderot's Encyclopédie entry on ‘Epicuréisme’ and his source material in Johan Jakob Bruker and Pierre Bayle demonstrates that Diderot used his discussion of Epicureanism to intervene directly in contemporary theological controversies over the immortal soul and a providential god.     

Facts and Philosophy in Neurophysiology. The 200th Anniversary of Johannes Müller (1801–1858)

Johannes Müller was the founder of the first school of physiology in Germany. His anatomical, morphological and physiological research as well as his epistemological view of scientific medicine opened the way to a deeper understanding of the structure and the function of the organism. With important discoveries like the law of sense energy, the reflex movement and the definition of different organic stimuli, he enriched the knowledge of neuroanatomy, neurophysiology and sensory physiology and smoothed the way to an experimental physiology. All his famous students like Hermann von Helmholtz, Emil Du Bois-Reymond, Ernst Brücke, Jakob Henle, Robert Remak, Rudolf Virchow and Ernst Haeckel solved many crucial research problems, which Müller identified and pointed out to them as open questions, due to the insufficient methods of investigation. Müller's research method, epistemological view of biological sciences, and his open-minded personal style encouraged the development of new methods adapted to particular problems.     

Naturalism and its political dangers: Jakob Thomasius against Spinoza's Theological-Political Treatise. A study and the translation of Thomasius’ text

ABSTRACT

Jakob Thomasius was a well-known professor who in 1670 chose to address a new anonymous text in a faculty lecture. The text was Spinoza’s Theological-Political Treatise (TTP). Five years earlier, Thomasius had attacked libertine philosophers in two other faculty lectures, and now explicitly links those lectures with this critique of the TTP. This article examines the argumentative strategy and structure of Thomasius’ 1670 lecture, in the light of those 1665 lectures, to see what it was that upset the Leipzig professor. Thomasius’ text is a rarity in that it aims to critique the TTP primarily on political grounds, not religious, but this sees Thomasius’ fear of naturalism assume strongly political tones of fear of faction. This article assesses Thomasius’ version of moderate censorship, the link he draws between Hobbes and innovation, his debt to Comenius, and the coherence of his defence of moderate Lutheranism. This article also provides a translation of Thomasius’ heretofore untranslated text.     

Gall’s German enemies

ABSTRACT

Franz Joseph Gall’s (1758–1828) proposal for a new theory about how to represent the mental faculties is well known. He replaced the traditional perception-judgement-memory triad of abstract faculties with a set of 27 highly specific faculties, many of which humans share with animals. In addition, he argued that these faculties are dependent on specific cortical areas, these being his organs of mind. After several years of presenting his new views in Vienna, he was banned from lecturing for what he considered absurd reasons. The edict enticed him to make a scientific journey through the German states, both to present his ideas to targeted audiences and to collect more cases. This trip, started in 1805, was extended to include stops in Denmark, Holland, and Switzerland before finally ending in Paris in 1807. For the most part, Gall was received with great enthusiasm in what is now Germany, but there were some individuals who strongly opposed his anatomical discoveries and skull-based doctrine. In this article, we examine the concerns and arguments raised by Johann Gotlieb Walter in Berlin, Henrik Steffens in Halle, Jakob Fidelis Ackermann in Heidelberg, and Samuel Thomas Soemmerring in Munich, as well as how Gall responded to them.     

A neolithic case of Down syndrome

The aim of the study is to draw attention to the existence of a Neolithic figurine from Greece with characteristics compatible with Down syndrome. We have reviewed the relevant medical and archaeological literature, and we have compared photographs of the figurine with photographs of a patient with typical Down syndrome (DS). From the above data we conclude that the 7000 years old artefact may well be the most ancient representation of the disease in Western civilisation.     

A neolithic case of down syndrome?*

Abstract

The aim of the study is to draw attention to the existence of a Neolithic figurine from Greece with characteristics compatible with Down syndrome. We have reviewed the relevant medical and archaeological literature, and we have compared photographs of the figurine with photographs of a patient with typical Down syndrome (DS). From the above data we conclude that the 7000 years old artefact may well be the most ancient representation of the disease in Western civilisation.     

Books in Summary

Darwinism and the Linguistic Image: Language, Race, and NaturalTheology in the Nineteenth Century, by Stephen G. Alter La Mythologie du Matriarcat, L'Atelie de Johann Jakob Bachofen, by Philippe Borgeaud with Nicole Durisch, Antje Kolde, Grégoire Sommer Social History: Problems, Strategies and Methods, by MilesFairburn Reflections on Revolutions, by Mark N. Katz Faces of History: Historical Inquiry from Herodotus to Herder, by Donald R. Kelley Who Do We Think We Are? Race and Nation in the Modern World, Philip Nicholson     

Securitizing infectious disease

Over the past decade there has been an increased awareness in the field of international relations of the potential impact of an infectious disease epidemic on national security. While states’ attempts to combat infectious disease have a long history, what is new in this area is the adoption at the international level of securitized responses regarding the containment of infectious disease. This article argues that the securitization of infectious disease by states and the World Health Organization (WHO) has led to two key developments. First, the WHO has had to assert itself as the primary actor that all states, particularly western states, can rely upon to contain the threat of infectious diseases. The WHO's apparent success in this is evidenced by the development of the Global Outbreak Alert Response Network (GOARN), which has led to arguments that the WHO has emerged as the key authority in global health governance. The second outcome that this article seeks to explore is the development of the WHO's authority in the area of infectious disease surveillance. In particular, is GOARN a representation of the WHO's consummate authority in the area of coordinating infectious disease response or is GOARN the product of the WHO's capitulation to western states’ concerns with preventing infectious disease outbreaks from reaching their borders and as a result, are arguments expressing the authority of the WHO in infectious disease response premature?     

Rates for the job. Measures of disease frequency in palaeopathology

Measures of disease frequency are discussed and their use in palaeopathology illustrated with examples, both hypothetical and real. It is shown that prevalence rates are the appropriate rates to use when calculating the frequency of diseases in skeletal populations. The extent to which prevalence rates accurately reflect those in the living population from which the skeletons were derived is also considered and it is suggested that they are a reasonable approximation for diseases that do not shorten life span, but not for those that do. Finally, suggestions are made for dealing with missing data.