Age‐Related Cortical Bone Maintenance and Loss in an Imperial Roman Population

This article explores age‐ and sex‐related patterns of cortical bone loss, assessed by radiogrammetry of the second metacarpal, from a skeletal sample excavated from the Imperial Roman port city of Velia (1st and 2nd century ad ), to contribute to our understanding of health and disease during the Imperial period. Patterns of age‐ and sex‐related bone loss and health at Velia are also compared with other historical samples and to modern clinical data. It was hypothesised that patterns of age‐ and sex‐related bone loss in this well‐represented Roman sample (n = 71) would mirror those reported in modern populations. Differences in the quantity of cortical bone between three age groups (18–29, 30–49 and 50+ years) are significant in both men and women; however, the pattern of bone loss differs between the sexes. Women show a gradual decline in bone quantity beginning in middle age, whereas men only lose bone in old age. However, there are no significant sex differences at any age group in the metacarpal cortical index. These findings suggest the hypothesis should be refuted because significant sex differences, particularly in old age, are an expected hallmark of bone loss in Western populations today. The possible biocultural and gender‐related factors that may have contributed to the observed patterns of bone maintenance and loss at Velia are discussed. Copyright © 2011 John Wiley & Sons, Ltd.     

The geochemical diversity of neogene clay deposits in Crete and its implications for provenance studies of Minoan pottery*

The determination of provenance probably forms the primary role of geochemical analyses in archaeological ceramic studies. In what has comprised a successful field of study, the ultimate basis for such research has been the comparison of pottery compositions with the geochemical diversity displayed by clay deposits within a given study area. Although such studies are now common, the understanding of chemical and mineralogical variability in ceramic raw materials has been somewhat neglected, with the dominance of assumptions rather than the actual analysis of clays. In this paper, a study is presented of Neogene clays in Crete (Greece), a clay type commonly used in ancient and modern pottery production. Sixty‐one samples were taken from 28 locations in the central and eastern parts of the island, to reveal both intra‐ and inter‐deposit variability. In one deposit chosen for multiple sampling, the 14 samples display great variability in the alkali elements, Fe and Co, and to a lesser extent in the REEs. Many of the geographically separate deposits differ from each other in chemical composition, with Eastern Cretan deposits showing higher REE concentrations and higher Th/Sc ratios, whereas Central Cretan deposits of younger geological stages are characterized by a lower Th/U ratio. Mineralogical analysis by XRD is used to explain aspects of the geochemical variability of the clays.     

The relationship of bone mineral density and other growth parameters to stress indicators in a medieval juvenile population

In this study the radii of 34 juveniles from Wharram Percy, a British medieval site, were measured for bone mineral density (BMD) using dual energy X‐ray absorptiometry (DXA) in order to investigate evidence of stress including Harris lines, cribra orbitalia and deficient cortical index, which is usually attributed to poor nutrition. BMD measurements are used in modern children to assess growth and development and generally correlate with linear growth. Only rare chronic illnesses affect bone mineral accrual in children. Radiographs of the radii were examined to assess cortical index and of the femora and radii for Harris lines. The results indicate that BMD is well correlated with dental age and linear growth, but is poorly correlated with cortical index. The variability in cortical index indicates the influence of environmental factors. There is no relationship between BMD and the presence or absence of Harris lines or cribra orbitalia. Thus, despite obvious evidence of skeletal stress in this juvenile population, bone was not under‐mineralised and bone mineral accrual proceeded normally with growth. This reinforces the conclusion that cortical index is a more sensitive indicator of environmental stress than either Harris lines or cribra orbitalia, and may be compared with BMD measurements to assess the effect of stress on growth. Copyright © 2005 John Wiley & Sons, Ltd.     

Compensatory bone remodelling in moose: a study of age,sex, and cross‐sectional cortical bone dimensions in moose at Isle Royale National Park

We studied interrelationships among age, sex, and cross‐sectional cortical bone dimensions using quantitative computed tomography (QCT) scans of metatarsal bones of 180 moose (Alces alces) that died in Isle Royale National Park, Michigan. As a large‐bodied quadruped with demanding ecological constraints on movement and behaviour, a moose experiences different weight‐bearing and mechanical stressors than humans, to whom most existing studies of mechanical adaptations of bone pertain. In moose, both sexes showed significant subperiosteal expansion and an increase in medullary area, with an overall increase in cortical bone area over time. Female moose did not exhibit cortical thinning or reduction in cross‐sectional area with age, rather they showed an increase in cortical bone area with periosteal apposition exceeding endosteal resorption, similar to the males. We also found that moose undergo changes in bone geometry through remodelling of bone similar to humans, suggesting a compensatory mechanism for increasing bone strength under conditions of decline in bone mineral density with age. Copyright © 2002 John Wiley & Sons, Ltd.     

Analysis of sexual dimorphism of craniofacial traits using geometric morphometric techniques

This work deals with the assessment of cranial sexual dimorphism in human skeletal samples applying geometric morphometric techniques. The purpose of this research is to apply such techniques to quantitatively describe in craniofacial traits the degree and pattern of shape and size sexual dimorphism. Likewise, we evaluate the precision and accuracy of semilandmark‐based techniques for sex estimation. We employ a sample of 125 adult skulls of known sex from the Coimbra collection. A set of coordinate points was selected to describe glabella, mastoid, frontal and zygomatic processes. The results of intra‐class correlation coefficient (ICC) show excellent intra‐ and inter‐observer agreement (ICC > 0.96) in the location of the coordinates of points employed. The principal component analysis (PCA) performed on shape variables shows a large superposition of both sexes, suggesting a relatively low degree of dimorphism in shape. As a consequence, the average percentages of correct sex estimations based on these variables were of 60.12 and 68.90%, obtained by discriminant analysis with leave‐one‐out cross validation and k‐means clustering respectively. Conversely, when centroid size is included in PCA, females and males exhibit large separation along the first component. The highest values of correct assignment (77.86 and 72.15%) were found using shape–size variables with discriminant and k‐means clustering analysis, indicating that the traits analysed display marked sex differences related to the larger size and more robust features of males. Finally, the advantages of geometric morphometric techniques are discussed. Copyright © 2009 John Wiley & Sons, Ltd.     

MODELLING CHANGES IN MOLLUSC SHELL INTERNAL MICROSTRUCTURE DURING FIRING: IMPLICATIONS FOR TEMPERATURE ESTIMATION IN SHELL‐BEARING POTTERY*

Firing experiments have been carried out on a clay containing naturally occurring fragments of mollusc shell. The transformation and/or decomposition of mineral phases with temperature was monitored by thermal analysis on the starting material and compared with X‐ray diffraction data on the fired specimens. Scanning electron microscopy revealed systematic changes in the internal microstructure of the shell fragments. Micrometer‐sized intra‐ and inter‐layer pores formed in the shells before the complete decomposition of calcite. The shape, dimension and location of the pores within the shell microstructure were found to be directly related to the firing temperature. The analysis of these microstructural features in archaeometric studies offers a good constraint on the estimation of the firing temperature in shell‐bearing pottery.     

Taphonomy and zooarchaeology of the Upper Palaeolithic cave of Dzudzuana,Republic of Georgia

We present the results of a detailed taphonomic and zooarchaeological study of the faunal remains from the Upper Palaeolithic layers of Dzudzuana Cave, Republic of Georgia. This study presents the first carefully analysed Upper Palaeolithic faunal assemblage from the southern Caucasus and thus serves as a significant point of reference for inter‐regional studies of Upper Palaeolithic subsistence in Eurasia. A series of intra‐site taphonomic comparisons are employed to reconstruct the depositional history of the bone assemblages within the different occupational phases at the site and to investigate subsistence, meat procurement and bone‐processing strategies. Caucasian tur (Capra caucasica), aurochs (Bos primigenius) and steppe bison (Bison priscus) were the major prey species throughout the Upper Palaeolithic. Their frequencies do not change significantly over time, and nor does bone preservation vary by layer. The assemblage is characterised by significant density‐mediated biases, caused by both human bone‐processing behaviours and in situ post‐burial bone attrition. Bone marrow extraction produced large numbers of unidentified bone fragments, many exhibiting green bone fractures. The density and size of bone assemblages and the extent of fragmentation indicate that Dzudzuana Cave was repeatedly occupied by Upper Palaeolithic foragers over many years. Skeletal part representation and butchery marks from all stages of carcass processing suggest that prey occasionally underwent field butchery. Intra‐site taphonomic comparisons highlight uniform patterns of cultural and economic behaviours related to food procurement and processing strategies. Copyright © 2007 John Wiley & Sons, Ltd.     

The chronology of epiphyseal union in the hand and foot from dry bone observations

Dry bone data for epiphyseal union at the hand and foot are scarce, incomplete or inexistent. This study documents the timing of fusion of secondary ossification centres at the hand and foot in a sample of known‐age human skeletons. The sample comprises 92 individuals (49 females and 43 males), between the ages of 9 and 22 years, from the identified skeletal collection curated at the National Museum of Natural History in Lisbon, Portugal. Epiphyseal union was recorded on the right and left side at the long bones of the hand (metacarpus and phalanges) and foot (metatarsus and phalanges), and also at the talus and calcaneus, using a three stage scheme (non‐fused; partially fused and completely fused). In the hand, intra‐observer agreement was 99% and inter‐observer agreement was 98%. In the foot, both intra‐ and inter‐observer agreement reached 100%. Lateral asymmetry was not significant and only 1.1% of the individuals in the sample were found to be asymmetric in the stage of epiphyseal fusion (1.8% in the hand and 0.3% in the foot). A minimum mean advancement of 1–2 years in females relative to males was observed. In the hand bones, epiphyseal union occurred between 12–18 years in females and 16–18 years in males. Comparatively, in the foot bones, epiphyseal union occurred slightly later, with the exception of the talus and calcaneus, which are the earliest bones to mature. Data in this study can be used to estimate the age of unidentified skeletal remains, either directly or by aiding in the modification of incomplete or imprecise data that have been collected over the years. Copyright © 2009 John Wiley & Sons, Ltd.     

Reconsideration of criteria for differentiating faunal assemblages accumulated by hyenas and hominids

Zooarchaeologists have established several criteria for differentiating hominid‐ and hyena‐derived faunal assemblages. In some cases, however, the patterns of skeletal part representation and bone surface modification on which these criteria are ultimately based have been observed in fossil bone assemblages of unknown origin, rather than in modern assemblages of known origin. When the proposed criteria are evaluated within an actualistic framework, only three are able to differentiate between hominid‐ and hyena‐created faunal assemblages. I suggest that only these three criteria—proportions of carnivores to ungulates in the assemblage, the preserved condition of long bone specimens (either as whole cylinders or as splintered shaft fragments), and the types of bone surface modifications—should be retained as important factors in a diagnosis of the ancient bone‐collector. The remaining four criteria—the relative proportion of horn pieces in the assemblage, the relative representation of podial bones, the relative representation of small and large bovid skeletal parts, and bovid mortality profiles—are not relevant or applicable to the problem of differentiating hominid‐ from hyena‐derived faunal assemblages. Copyright © 2002 John Wiley & Sons, Ltd.     

Cortical index of three prehistoric human Pacific Island samples

To understand stress, attention must focus on the costs and limits of adaptation. The current study investigates two non‐specific indicators of stress in human skeletal remains from three prehistoric sites in the Pacific Islands as an attempt to understand differential responses to island environments. The samples used in this study represent both colonising and established populations and are spread geographically throughout the Pacific Islands. In the current study both inter and intrasample comparisons of cortical index (CI) and maximum femoral length are made. Within all the samples there is evidence of an age related decline in CI and a sexual dimorphism of CI and maximum femoral length. No significant correlations are found between the non‐specific indicators of stress and the temporal and spatial distributions of the samples. Overall, the indicators used in the current study show very similar results and therefore do not seem to reflect differential adaptation to Pacific Island environments through time and across island groups. Copyright © 2010 John Wiley & Sons, Ltd.     

Industrial clusters,organized crime,and productivity growth in Italian SMEs

We examine whether organized crime affects firms’ performance (defined using Total Factor Productivity growth) both directly and indirectly, by downsizing the positive externalities arising from the geographic concentration of (intra‐ and inter‐industry) market‐related firms. The analysis uses a large sample of Italian small‐ and medium‐sized manufacturing firms over the period 2010–2013. The results highlight the negative direct effects of organized crime on firms’ productivity growth. Any positive effect derived from industrial clustering is thoroughly debilitated by a strong presence of organized crime, and the negative moderation effect of organized crime on productivity growth is greater for smaller than for larger firms.     

Commonwealth perspectives on International Relations

The parallel development of the inter‐ and non‐governmental Commonwealths on the one hand and the field of International Relations and its oldest journal, The Round Table, on the other, should not go unnoticed at the start of the second decade of the century. This article suggests that the Commonwealth nexus has always constituted a distinctive perspective and debate in both the metropole and the rest of the Commonwealth's expanding official and unofficial networks. The Commonwealth 'School’ both reinforces and contrasts with other non‐US and non‐hegemonic approaches presently animating the field.     

Diameter of the human internal acoustic meatus and sex determination

We report the results of testing the diameter of the internal opening of the acoustic canal in the petrous part of the temporal bone for sex determination of skeletal remains. The method involves measuring the diameter using a suite of ordinary drills. The method is very simple and has the great advantage of utilising one of the sturdiest bone elements of the human skeleton. The method may be especially useful for the analyses of very fragmented skeletal remains or cremated bones, where the petrous bone may still be readily recognisable. The method was tested using a forensic sample of 113 left petrous bones with known sex. Intra‐ and inter‐observer testing was also performed. We found a statistically significant difference in diameter between males and females (means: males: 3.7 mm; females: 3.4 mm; P < 0.009). However, the low predictive value (70%) for correct sexing using two sectioning points ( < 3.0 mm = female; >3.5 mm = male) was disappointing. No additional accuracy was gained by employing both left and right petrous bones (a bilateral sample of 60 petrous bones was also tested), although left and right side diameter is highly correlated (R = 0.778; P = 0.0001). Copyright © 2005 John Wiley & Sons, Ltd.     

The New ‘Coimbra Method’: A Biologically Appropriate Method for Recording Specific Features of Fibrocartilaginous Entheseal Changes

This paper presents a revised version of the Coimbra method for recording fibrocartilaginous entheses. The method itself is the only biologically appropriate recording method for fibrocartilaginous entheses that scores features separately, thereby ensuring that the aetiology of individual features can be studied. The method divides the enthesis into two zones, scoring the relevant features in each zone. These features represent either bone formation or bone destruction and include erosive lesions, fine and macro‐porosity, and cavitations. The revised method includes a new feature, textural change, which is scored as absent or present when it involves 50% or more of the surface. All other features are now scored as zero (absent), one or two with the higher score representing greater expression of the feature. This change in scoring has led to the reduction of inter‐observer error with approximately 80% agreement for overall feature scores for both the common extensor origin and subscapularis insertion. The simplification of the scores and the reduction in inter‐observer error mean that the method is now recommended for widespread use. Copyright © 2015 John Wiley & Sons, Ltd.     

Morphological changes in the shape of the non‐pathological bony knee joint with age: a morphometric analysis of the distal femur and proximal tibia in three populations of known age at death

This study examines possible morphological variation in the knee joint of Homo sapiens with increasing age in ostensively healthy and non‐pathological distal femora and proximal tibiae. Throughout the lifetime of each individual, the hard tissue of the knee undergoes considerable remodelling as a response to biomechanical stresses, changes in bone microarchitecture and reduction of bone mineral content as a concomitant of ageing. The knee is also subject to greater levels of degenerative joint disease than any other joint. If death occurs whilst such diseases are in the earliest stages, initial bone changes may not be visually obvious in museum specimens. If such specimens are used for comparative analyses, it is hypothesised that changes might render it problematic if all ages are conglomerated into discrete samples. This study therefore investigates the degree to which the distal femur and proximal tibia change shape during ageing and, if changes are present, whether they are expressed similarly in males and females. It also examines whether changes are of greater magnitude than those morphological differences which might exist between populations. In an example population of African‐Americans, results indicate that there is a statistically significant difference in shape between age groups and those differences become progressively greater between the youngest and oldest adults. Results also show that although morphological variation caused by ageing is apparent, those shape differences attributable to sexual dimorphism are more powerful. When two additional populations are analysed jointly with the African‐Americans (Caucasian Americans and the European Spitalfields sample), results indicate that inter‐population shape differences are considerably greater than differences caused by increasing age. Results imply that it is justifiable to combine specimens of all ages into discrete samples for comparative purposes. Copyright © 2007 John Wiley & Sons, Ltd.     

An investigation of cortical bone loss and fracture patterns in the neolithic community of Çatalhöyük,Turkey using metacarpal radiogrammetry

Bioarchaeologists have conducted numerous studies on human skeletal remains using metacarpal cortical bone radiogrammetry. This method allows cortical thickness of the second metacarpal to be quantified. As a sensitive index of bone health metacarpal cortical thickness is evaluated in the context of functional adaptations, growth, ageing and bone loss in osteoporosis, as well as used as a reliable indicator of fracture risk. The focus of this study is an examination of the widely used calculation that expresses second metacarpal cortical bone values, followed by an examination of age and sex-related patterns of cortical bone loss and skeletal fragility fracture in a Neolithic archaeological skeletal sample from Çatalhöyük, Turkey. Using metacarpal radiogrammetry, 49 adult metacarpals (f = 27 m = 22) were examined. Data were collected for size variables, length (L) and total bone width (TW) as well as quantity variables, medullary width (MW) and cortical thickness (CT). These parameters were then used to calculate the widely used cortical index (CI) and two new indices expressing medullary width and cortical bone thickness in relation to length (medullary width index, MWI and cortical thickness index, CTI). The ratios were then used to explore age- and sex-related cortical bone loss and fragility fracture patterns amongst the inhabitants of Çatalhöyük. Çatalhöyük males and females demonstrate an inverse relationship where CTI decreases as age and MWI increase. Analyses indicate statistically significant age-related change in MWI amongst the oldest females. Despite age-related loss of bone, no typical fragility fractures are observed. We discuss the role of ageing and lifestyle factors at Çatalhöyük that may have been beneficial to skeletal health and a reduction in the risk of fragility fracture.     

Metacarpal radiogrammetry: a useful indicator of bone loss throughout the skeleton?

Metacarpal radiogrammetry has received increasing interest in recent studies of archaeological human bone in facilitating the identification of age-related cortical bone loss and osteoporosis risk in the past. The technique is relatively simple and non-destructive, and existing comparative clinical data is an advantage in its application to archaeological samples. In order for metacarpal radiogrammetry to be useful in identifying individuals that could have been at risk of fracture in the past, cortical bone loss as measured at the second metacarpal is assumed to be reflective of bone loss occurring throughout the skeleton and across the metabolically different cortical and trabecular bone. Archaeological studies have frequently relied on literature reviews of clinical data to justify the technique as valid and useful. However, the present study has examined whether cortical bone loss measured in the second metacarpal is similar to bone loss measured at specific skeletal sites that are more frequently affected by osteoporosis-related fracture. Skeletons from two post-medieval collections from London, UK, Redcross Way and Farringdon Street (lower burial ground of St. Bride's Church) were studied. The results of the present study demonstrate that the second metacarpal is useful in identifying age-related bone loss at sites that are predilected to osteoporotic fracture, most notably the distal radius, which is prone to Colles' fractures. Metacarpal radiogrammetry also correlates well with bone loss in skeletal sites that are primarily composed of trabecular bone, including the fourth lumbar vertebra (a site of compression fractures) and the iliac crest (the location for clinical biopsies). The present study also confirms previous findings of significant differences between the pattern of cortical bone loss between the metacarpal and the femur. The poor relationship between these two areas is most likely attributable to mechanical loading.     

Implementing Cleaner Production Programmes in Changzhou and Nantong,Jiangsu Province

Cleaner Production (CP) has been advocated worldwide as a strategy for companies to obtain environmental and economic benefits simultaneously. This analysis of how city‐level CP programmes were implemented in Changzhou and Nantong (Jiangsu Province, China) finds that both cities failed to meet the Province's targets to implement CP at all large‐ and medium‐sized companies by the end of 2000. Ineffective vertical control, weak inter‐agency co‐ordination, and lack of alignment between CP requirements and the core missions and operating procedures of implementing agencies have impeded CP implementation in the two cities. The relatively few successful CP outcomes at companies are based on the professionalism and skills of individual implementing agents. However, successes that rely exclusively on individual agents may not last, and thus institutional changes will be needed if the government's CP programmes are to lead to broader CP adoption.     

NDVI variation and its relation to climate in Canadian ecozones

Parks Canada began the Northern Satellite Monitoring Program in 1997, with the objective of tracking large‐scale vegetation variation in Canadian ecosystems and helping land managers to develop appropriate management practices in response to climate change. Under this program, a sequence of 10‐day composite Advanced Very High Resolution Radiometer (AVHRR)‐derived Normalized Difference Vegetation Index (NDVI) data from 1985 to 2007 was examined to study seasonal and inter‐annual relationships between vegetation and climate data over Canadian ecosystems using statistical and wavelet analysis. Statistical analysis showed that temperature was the principal driver for seasonal variability in greenness, explaining more than 70 percent of seasonal variation in vegetation for most Canadian ecozones. In comparison with temperature, the relationships between NDVI and precipitation were weaker but still significant. Maximum annual NDVI showed increasing trends in Canadian ecozones during the study period, although increasing rates were spatially heterogeneous. Wavelet analysis confirmed that inter‐annual variation in NDVI was different at two ecozones in Canada. NDVI variation in the Northern Arctic was significant at scales of 3–4 years from 1997 to 2001, which was associated with temperature and precipitation variation. Comparatively, NDVI variation in the Boreal Shield was significant at scales of 5–8 years from 1991 to 1999, but did not correspond with climate variation.     

CT and micro‐CT analysis of a case of Paget's disease (osteitis deformans) in the Grant skeletal collection

This paper presents a case study in which Paget's disease of bone is differentially diagnosed in an individual from the Grant skeletal collection using non‐destructive computed tomography (CT) and micro‐computed tomography (micro‐CT) analyses of the pubis, in addition to plain film radiography and macroscopic examination. In archaeological and modern osteological samples diagnosis frequently relies on macroscopic examination, plain film radiography and histological examination of bone samples. CT and micro‐CT modalities provide researchers with a non‐destructive view of the internal structure of bone unhampered by the superimposition that is characteristic of plain film radiographs. Given the importance of the increased cortical and trabecular thickness in the differential diagnosis of Paget's disease, these techniques are ideal means by which to non‐destructively examine culturally‐sensitive and scientifically‐valuable human remains for signs of Paget's disease of bone. Copyright © 2009 John Wiley & Sons, Ltd.