More than a Disease: The History of General Paralysis of the Insane in Turkey

This article explores the history of general paralysis of the insane (GPI) and its treatment in Turkey. GPI was considered as “a disease of civilization” at the end of the nineteenth century. From the early years of the twentieth century, Turkish psychiatrists discussed and interpreted the causes of GPI and followed the European diagnostic and treatment methods of the disease. Austrian psychiatrist Julius Wagner-Jauregg (1857–1940) introduced and developed “malaria fever therapy” for general paralysis in 1917. Malaria fever therapy spread to other countries and, during the 1920s, the treatment was also used in Turkey. This article not only aims to illuminate an unnoticed aspect of the history of psychiatry in Turkey but also uses GPI as a model to illustrate how psychiatry in Turkey was influenced by the developments in Europe.     

The Spatial Dynamics of Epidemic Diseases in War and Peace: Cuba and the Insurrection against Spain, 1895–98

This paper examines the spatial transmission and rate of propagation of three infectious diseases (enteric fever, smallpox and yellow fever) in times of war and peace in Cuba between 1895 and 1898. For the three diseases studied, the analysis will demonstrate that, compared with peacetime, the Cuban Insurrection caused increased epidemiological integration of the settlement system of Cuba, acceleration of the spatial processes of disease transmission and a marked change in the geographical drift of infectious disease activity. While the first two findings may be attributed to the heightened levels of population mixing that accompanied the insurrection, the third implies that hostilities fundamentally altered the spatial courses of diseases. These changes transcended stark biases in the predisposition to infection among Spanish soldiers (to yellow fever) and Cuban civilians (to smallpox). Finally, it is shown that the military were the prime agents causing contrasts in the epidemiological experience of Cuba between war and peace.     

Application of Health Expectancy Research on Working Male Population in Bangladesh

Lower quality of life and more work-loss days for the workforce are barriers for economic development in Bangladesh. Using nationally representative data—the Bangladesh Demographic and Health Surveys for the 2004–2007 period, we examined the prevalence of diseases (asthma, diabetes, heart problems, high blood pressure, jaundice/hepatitis, malaria/fever, tuberculosis, and other) that prevented ever-married male workers from doing their regular activities in Bangladesh, and we examined changes in partial work-loss free life expectancy (WLFLE). The study found improvements in the mean number of work-loss days as well as in WLFLE; male workers at age 30 in 2007 expected 212 days more WLFLE than male workers of the same age in 2004. Other diseases prevented 17.8 per cent of male workers in 2004 and 9.1 per cent of male workers in 2007 from doing their normal work. Malaria/fever prevented 14.4 per cent and 11.5 per cent of male workers in 2004 and 2007, respectively, from doing their normal work. In both years, of all the diseases, the other diseases category and malaria/fever were found to be the major causes preventing Bangladeshi male workers from doing their normal work. This study recommends taking action against malaria/fever so that people can continue working without health problems or illness, and it recommends identifying other diseases which cause work-loss days. It suggests collecting data for both the males and females in a consistent manner by keeping the same questions with the same wording, order, and age groups consistent over time.     

A history of acute bacterial meningitis

Although meningitis was not yet known as such, its symptoms have been conceptualized in different ways and many theories about its causes have been formulated in the course of time. Terms like hydrocephalus and brain fever were used for different clinical manifestations of what today would be recognized as meningitis. Pathological-anatomical findings led to the emergence of the clinical entity from several old concepts of disease. Initially, diagnostic means were limited and therapeutic methods did not differ much from those that had been applied for centuries, even far into the nineteenth century. Discoveries in bacteriology and the introduction of the lumbar puncture provided a new paradigm for knowledge of the pathophysiology and treatment of what then became known with the term meningitis. The development of new therapeutic methods including antiserum, sulfonamides, and penicillin resulted in a decreasing mortality during the past century. Nowadays, with the use of antibiotics, bacterial meningitis can often be cured.     

Perkins’s patent metallic “Tractors”: Development,adoption, and early dissemination of an eighteenth-century therapeutic fad

ABSTRACT

The metallick Tractors were patented by Elisha Perkins, a Connecticut physician, in 1796, for the treatment of various ailments, particularly those associated with pain. They were subsequently rapidly and widely disseminated on the basis of testimonials and aggressive marketing tactics. Dissemination was facilitated by endorsements from prominent physicians, politicians, and clergy, by quasi-theoretical explanations of efficacy based on then-current experiments of Galvani and others, and by the apparent simplicity and safety of the procedure. Abandonment of this ineffective therapy was later prompted by the application of blinded placebo-controlled trials using sham devices.     

Neurognostics Question: An American Neurophysiologist,Pioneer of Electromyography,A President of Universities and Scientific Advisor to United States Presidents

The semantics of pain are an important and interesting aspect of any language. Ancient Greek and Latin had multiple words for pain, which makes scrutinizing different meanings problematic. The ancient physician Galen approached this issue through the use of adjectives to describe the qualities for pain, instead of the words for pain themselves. The medical texts of Celsus and Caelius Aurelianus reveal that Latin also vested particular significance in qualifiers to distinguish between different types of pain. This article looks at the qualifying terms used for pain in the ancient Greek and Latin languages to reveal a sophisticated Greco-Roman vocabulary for pain.     

Diagnosis versus Dialogue: Oral Testimony and the Study of Pediatric Pain

Abstract: Through the perspectives of the children, this essayexamines the communication between pediatric pain patients andtheir doctors. Based upon the oral history responses of thirty-twopatients with chronic pain present for evaluation at the PediatricPain Clinic at UCLA, oral testimony was employed to uncovera wide range of topics related to a child's experience withpain such as family dynamics, how and when pain became a life-changingfactor, coping strategies, and external sources that contributeto the child's understanding of pain. Most important, childrenwere encouraged to explain what it was like to be in pain, notonly to describe symptoms but also to share their dreams andhopes, their fears and uncertainties—as well as the placeof pain in their world.     

Veterinary immunology as colonial science: method and quantification in the investigation of horsesickness in South Africa, C. 1905-1945

This article examines the practice of veterinary immunology in South Africa during the first half of the twentieth century through an analysis of research into a horsesickness vaccine at the Onderstepoort Veterinary Institute. From the early 1900s, Arnold Theiler prioritized research into horsesickness, by then defined as an insect-borne disease caused by an ultravisible virus. He succeeded in devising a means of prophylaxis using a simultaneous injection of infective blood and immune serum, but he discovered antigenically different strains of the virus, which could overcome the immunity produced by his treatment. The practical value of Theiler's methods was further limited by difficulties in standardizing the biological material used in immunization, the results of which remained too erratic for application on a large scale. No further advances were made until the 1930s, by which time Onderstepoort had been drawn more closely into international scientific networks. Using techniques derived from research into yellow fever in America and canine distemper in Britain, the Onderstepoort scientist Raymond Alexander invented a method of immunization that utilized the propagation of the horsesickness virus in the brains of mice. Alexander's methods, which were characterized by successful technical adaptation and innovation, depended upon methods of quantification first developed by Paul Ehrlich to standardize diphtheria antitoxin during the 1890s. During the 1940s, vaccination expanded rapidly in South Africa, and Onderstepoort later exported the vaccine and associated technology to other countries affected by horsesickness.     

Schmorl's nodes: clinical significance and implications for the bioarchaeological record

Back pain is one of the major contributors to disability and loss of productivity in modern populations. However, osteological correlates of back pain are often absent or, as yet, unidentified. As bioarchaeologists depend on osteological evidence to interpret quality of life in the past, back pain, with its profound effects on modern populations, is largely overlooked in archaeological samples. This study addresses this shortcoming in bioarchaeological analysis by exploring the relationship between a defined vertebral osteological lesion, the Schmorl's node, and its effect on quality of life in a clinical population. Using patient insight, healthcare practitioner diagnoses and MR imaging analyses, this study investigates: (1) Schmorl's nodes and sociodemographic factors; (2) the number, location and quantitative aspects (e.g. length, depth, area) of Schmorl's nodes, and how these influence the reporting of pain; (3) the dynamic effects of Schmorl's nodes, in combination with other variables, in the reporting of pain; and (4) the perception and impact of pain that patients attribute to Schmorl's nodes with regard to quality‐of‐life issues. The results of this study indicate that Schmorl's nodes located in the central portion of the vertebral body are significantly associated with patient reporting of pain, and that the presence of osteophytes, in the affected vertebral region, may increase the likelihood that an individual will report pain. This finding provides bioarchaeologists with an osteological correlate to begin interpreting the presence and impact of pain in archaeological populations, with implications for scoring Schmorl's nodes. Copyright © 2007 John Wiley & Sons, Ltd.     

How the mosquito (man) liberated Cuba

Disease is a more efficient killer of armies than man, but military historians tend not to dwell on this fact, for fear of relegating human volition to a secondary role in the outcome of wars. Thus, studies of the Cuban War of Independence from 1895 to 1898 tell of thrilling machete charges and awe-inspiring battleships, but pay insufficient attention to the insects and microbes that really killed the Spanish army and prepared the ground for the liberation of Cuba. This essay argues that the mosquito and yellow fever did most of the work of freeing Cuba from Spanish military occupation. It also tells how the theory of a Cuban physician, Carlos Finlay, helped to liberate the island from yellow fever following the American occupation in 1898. In this way the essay unites two sundered histories that belong together, and then goes on to explain why the medical community ignored Finlay for almost 20 years, just time enough to allow Cubans to found a new nation.     

Towards an Archaeology of Pain? Assessing the Evidence from Later Prehistoric Bog Bodies

This paper highlights the potential for what could be termed an ‘archaeology of pain’, reflecting on the potential significance and role of the infliction, suffering, endurance and observation of pain by individuals in the past. It presents a case study of ‘bog bodies’, human remains recovered from wetland which, due to the anoxic, waterlogged conditions, preserves human flesh and associated evidence, including injuries and cause of death. The central argument is that evidence from pathological investigations of certain later prehistoric bodies provides hitherto neglected information concerning the embodied experience of pain, in particular its duration and intensity, which may be central to the interpretation of these events. This understanding can be framed not only in terms of the experience of pain by the victims, but also in the potential perception of pain and suffering by those inflicting these and potentially by any observers of the final moments of these individuals.     

抗战时期华北根据地的卫生防疫工作述论

抗战时期华北根据地疾疫流行广泛,疟疾、痢疾、伤寒、麻疹和流行性感冒等尤为严重。边区政府和军队从"一切为了战争胜利"的目的出发,积极建立各级卫生组织,颁布卫生防疫法规,开展积极的卫生防疫宣传和广泛的群众性卫生运动,切实实施包括组建各种医疗组和卫生防疫队、帮助各级政权训练卫生防疫人员、协助地方卫生工作、充分发挥中医中药的作用等各种卫生防疫办法,不仅有效地预防和控制了各种疾疫的流行,巩固了根据地的社会稳定,而且转变了根据地民众的卫生观念,破除了根据地民众落后的封建迷信思想,增进了广大民众对边区政府和军队普遍的政治认同,为其后的卫生防疫工作尤其是新中国的疾疫救治和卫生防疫体系的建立提供了丰富的经验。     

Cinchona and Quinine: A Remarkable Anniversary

Abstract

The use of the bark of the 'fever tree', cinchona, to cure intermittent fevers was first described in print by an Augustian monk in 1638, just over 350 years ago. The discovery and the first records are here chronicled. As such fevers were widespread, demand for the bark increased greatly, and attempts were made to establish cinchona tree plantations in tropical zones, most of them unsuccessfully. Only Dutch commercial production in what is now Indonesia was profitable. Chemical synthesis of antimalarial drugs reduced natural production of quinine for a time, but as drug resistance among the parasites that cause the malaria has increased, culvitation of the natural source has again become important.     

Sichuan’s promotion of education and activities of felling temple trees in the late Qing Dynasty

During Sichuan’s promotion of education in the late Qing Dynasty, trees in the domain of Buddhist or Daoist temples, which were part of temples’ property, had been felled across the province. The profits gained were used to repair or build schools as well as to fund their management. In different regions, the characteristics and intentions of the felling activities differed. Meanwhile, such fever gave rise to corrupt practices of deceitfully seeking profits which in turn caused numerous disputes and lawsuits, reflecting the confrontation provoked between the state and the people as well as different communities over tradition, ritual, and belief. The investigations of felling temple trees could enrich the understanding of provincial promotion for education in the late Qing period, and that of the social and cultural changes taking place in rural communities in modern times.     

神秘介质与吉本芭娜娜的小说风格

本文将吉本芭娜娜神秘小说分为三种主要类型,认为《月影》是对日本古代神话传说的发想;《哀愁的预感》是对悬疑小说的一种再创造;《甘露》则是集中展示神秘精神的文本。同时认为,神秘介质与吉本芭娜娜的小说风格之间之所以呈现出上述关系,与作家幼年时代的特殊经历,当代日本社会宗教热的走向与影响不无关系。     

Phantoms in Artists: The Lost Limbs of Blaise Cendrars,Arthur Rimbaud,and Paul Wittgenstein

There have been an increasing number of reports of postamputation pain and problems linked to phantom limbs over recent years, particularly in relation to war-related amputations. These problems, which are often poorly understood and considered rather mysterious, are still relevant because they are difficult to treat medically. Functional neuroimaging techniques now enable us to better understand their pathophysiology and to consider new rehabilitation techniques. Phantom limbs have often been a source of inspiration to writers, particularly in the period following the First World War, which was responsible for thousands of amputees. Some artists have suffered from postamputation complications themselves and have expressed them through their artistic works. Blaise Cendrars (1887–1961), one of the greatest authors of the twentieth century, suffered from stump pain and phantom limb phenomena for almost half a century following the amputation of his right arm during the First World War. He suffered from these phenomena until the end of his life and his literary work and personal correspondence are peppered with references to them. Arthur Rimbaud (1854–1891), one of the most famous poets in world literature, developed severe stump pain after his right leg was amputated due to a tumor. He survived for only six months after the procedure but left behind an account of the pain he experienced in correspondence to his family. The famous pianist Paul Wittgenstein (1887–1961), whose right arm was amputated during the First World War, became a famous left-handed concert pianist. The phantom movements of his right hand helped him to develop the dexterity of his left hand. The impact on the artistic life of these three men provides an original illustration of the various postamputation complications, specifically phantom limbs, stump pain, and moving phantom.     

Perennial crisis and the loss of flexibility

Crisis interrupts routine in unwelcome ways with an uncertain outcome. The Greek word krisis (κρíσις), which is etymologically close to criterion and criticism, was occasionally used in relation to social ailments. However, more often, it was used to refer to a medical condition characterized by a high fever. A critical condition in English and other European languages refers to a similar situation. Two possible outcomes were envisioned in ancient Greece: you died or you recovered. In the contemporary world, the term ‘crisis’ can be of limited relevance since crisis is endemic and chronic in one or several domains virtually everywhere. There are two general causes for this: accelerated, runaway globalization generates unpredictable, unintentional side effects; and different parts of a lifeworld change at different speeds, leading to disjunctures and destabilization. Perhaps volatility is a more appropriate term.     

国际合作抑或金融监管——以胡佛与斯特朗对欧洲经济重建分歧为中心

作为1920年代美国经济外交的重要制订者和参与者,胡佛和斯特朗都支持美欧经济合作,并鼓励美国民间私人力量参与一战后欧洲的重建,但面对美国对外贷款及其带来的国内投机,二人的分歧也日益突出。胡佛和斯特朗之间分歧反映了他们在欧洲重建方面不同的利益诉求,其背后则是美国不同利益集团的矛盾和冲突。而这种分歧和冲突导致了美国国内的对外经济决策权力分散和碎化,缺乏有力的决策核心,使美国的对欧政策缺乏一致性和连续性,并自相矛盾。