The White Paper: Wilder Penfield,the Stream of Consciousness,and the Physiology of Mind

ABSTRACT

Wilder Penfield is justly famous for his contributions to our understanding of epilepsy and of the structure-function relationship of the brain. His theory on the relationship of the brain and mind is less well known. Based on the effects of the electrical stimulation of the cortex in conscious patients, Penfield believed that consciousness and mind are functions of what he referred to as the centrencephalic integrating system. This functional system comprised bidirectional pathways between the upper brainstem, the thalami, and the cerebral cortex of both hemispheres, and was the physical substrate from which memory, perception, initiative, will, and judgment arose. It was the source of the stream of consciousness and the physical basis of mind. This paper reviews how Penfield arrived at this conception of the mind-brain relationship. Although Penfield ultimately felt that he had failed in his attempt to unify brain and mind, his work shed new light on the relationship of memory to the mesial temporal structures and to the temporal cortex; and his association of consciousness and the brainstem preceded the conceptualization of the reticular activating system by a generation. In these, as in so many aspects of neurobiology, Penfield was prescient.     

Neuronomy,education, and outreach in neuroscience: A historical case study of Burt Green Wilder

Burt Green Wilder (1841–1925) was a pioneering naturalist and anatomist who is historically known for his brain collection and for his contributions to neuroanatomical nomenclature. During his 42-year career, Wilder also used brain measurements for education and outreach, especially in regard to issues of race and gender. Additionally, Wilder influenced neuroscience education and acted as a scientific liaison to the public. For example, he designed early implementations of the sheep brain dissections that are still being conducted today, as well as likely conducted the first “Brain Day.” This article reviews each of these topics, as well as others, with the aim of accurately placing Wilder in the history of neuroscience as a naturalist and anatomist who, among other achievements, pioneered the use of brain measurements for education and outreach.     

The Reward of a King: Machiavelli,Aquinas, and Shakespeare's Richard III

Abstract

Richard III centers on the rise and fall of a man who claims that he will “set the murderous Machiavel to school” and proceeds to seize the crown of England, only to lose his grip on that coveted prize in his own sudden personal and political unraveling. Insofar as we see Richard as a genuine but failed Machiavellian, it remains difficult to determine the extent to which Shakespeare's critique of Richard is a critique of Machiavelli. Yet Shakespeare's account of Richard's hopes, successes, and failures, examined in light of relevant classical texts, points to fatal flaws in Machiavelli's account of reason, conscience, and the end of human actions, demonstrating that the concept of the objective good is an essential component of any meaningful and coherent account of human action. Thus, Richard's ultimate descent into madness is a sign of the fate that even the “best” Machiavellian statesman or society is destined to share.