Yorkshire’s influence on the understanding and treatment of mental diseases in Victorian Britain: The golden triad of York,Wakefield, and Leeds

In the late-eighteenth and nineteenth centuries, a more humane approach to the care of the insane in Britain was catalyzed in part by the illness of King George III. The Reform Movement envisaged “moral” treatment in asylums in pleasant rural environments, but these aspirations were overwhelmed by industrialization, urbanization, and the scale of the need, such that most asylums became gigantic institutions for chronic insanity. Three institutions in Yorkshire remained beacons of enlightenment in the general gloom of Victorian alienism: the Retreat in York founded and developed by the Quaker Tuke family; the West Riding Lunatic Asylum in Wakefield led by Sir James Crichton-Browne, which initiated research into brain and mental diseases; and the Leeds Medical School and Wakefield axis associated with Sir Thomas Clifford Allbutt, which pioneered teaching of mental diseases and, later, the first Chair of Psychiatry. Three other Yorkshiremen who greatly influenced nineteenth-century “neuropsychiatry” in Britain and abroad were Thomas Laycock in York and Edinburgh, and Henry Maudsley and John Hughlings Jackson in London.     

The Third Man: Robert Dunn’s (1799–1877) Contribution to Aphasia Research in Mid-Nineteenth-Century England

Throughout his medical career, Robert Dunn (1799–1877) published a number of clinical cases with postmortem reports involving acquired language disorders, with the first noted in 1842. He developed a physiologically informed approach to psychological function during the 1850s along with a group of notable colleagues Benjamin Collins Brodie, Henry Holland, Thomas Laycock, John Daniel Morell, and Daniel Noble. He was also active in ethnographic research on human origins and racial diversity. As such, Dunn represents an interesting player in the developing fields of neurology, psychology, and anthropology in England in the latter part of the nineteenth century. These various strands converged at the meeting of the British Association of the Advancement of Science in 1868, where Dunn shared the program of lectures on the cutting-edge topic of aphasia with Paul Broca (1824–1880) and John Hughlings Jackson (1835–1911). Dunn’s ideas developed over a longer time frame than his younger colleagues and as such represent a unique blending of concepts from the earlier work of Franz Josef Gall (1758–1828) and Jean-Baptiste Bouillaud (1798–1881) to the perspectives on language organization in the brain developed after 1861.     

The Transition from Animal Spirits to Animal Electricity: A Neuroscience Paradigm Shift

The Animal Spirits Paradigm had been in place for over a thousand years as a general way of looking at the nervous system, and was completely ingrained into the fabric of scientific thinking. However, the community of researchers in the 17th and 18th centuries abandoned their long-held assumptions, and started anew with the novel assertion that the currency of nervous function was, instead of Animal Spirits, a uniquely-animal electricity. This conceptual rearrangement represented a scientific revolution in thinking, a change in absolute perspective that required the reinterpretation of old data within a completely novel framework. The manner in which this transition occurred followed the general form of scientific paradigm shifts as outlined by Thomas Kuhn (Kuhn, 1962)     

The transition from animal spirits to animal electricity: a neuroscience paradigm shift

The Animal Spirits Paradigm had been in place for over a thousand years as a general way of looking at the nervous system, and was completely ingrained into the fabric of scientific thinking. However, the community of researchers in the 17th and 18th centuries abandoned their long-held assumptions, and started anew with the novel assertion that the currency of nervous function was, instead of Animal Spirits, a uniquely amimal electricity. This conceptual rearrangement represented a scientific revolution in thinking, a change in absolute perspective that required the reinterpretation of old data within a completely novel framework. The manner in which this transition occurred followed the general form of scientific paradigm shifts as outlined by Thomas Kuhn (Kuhn, 1962)     

REVIEWS

Collective Violence. Edited by James F. Short, Jr., and Marvin E. Wolfgang. Ancient Polynesian Society. By Irving Goldman. New Guinea Highlands Pidgin: Course Materials. By S. A. Wurm. Materials in New Guinea Pidgin (Coastal and Lowlands). By Don Laycock. Land Tenure and Economic Development. Problems and Policies in Papua-New Guinea and Kenya. Marion M. Ward (editor).     

Carn Alw as a source of the rhyolitic component of the Stonehenge bluestones: a critical re-appraisal of the petrographical account of H.H. Thomas

The source of the Stonehenge bluestones was first determined in the early 1920s by H.H. Thomas who was an officer with the Geological Survey of England and Wales. He determined that the so-called ‘spotted dolerites’ could be petrographically matched to a small number of outcrops in the Mynydd Preseli district in south-west Wales. The bluestones, however, comprise a number of additional lithologies, including rhyolite and ‘calcareous ash’, as well as various sandstones. Thomas was convinced that the volcanic lithologies in the bluestone assemblage were all sourced from a small area at the eastern end of the Mynydd Preseli, with the rhyolites originating from the prominent outcrop known as Carn Alw. Recently, provenancing of these rhyolites to Carn Alw has been questioned on the evidence of whole-rock geochemistry. This raised concerns over the original petrographical attribution. Accordingly a re-investigation was undertaken of the rhyolite petrography by re-examining the original specimens used by Thomas. Three of the original four thin sections studied by Thomas were re-examined, along with a newly made thin section from the fourth of Thomas' rock samples as the original thin section could not be located. The new petrographical evidence demonstrates convincingly that the two pairs of thin sections from the Preseli and Stonehenge as examined by Thomas do not match despite his contention and argues strongly that Carn Alw is not the source of the Stonehenge rhyolites which Thomas described. This reinforces the geochemical evidence presented recently and supports the contention that Craig Rhos-y-felin, to the north of Mynydd Preseli, is an important source of rhyolitic debris in the Stonehenge Landscape. Nevertheless, there remain uncertainties over the provenance of other Stonehenge rhyolites (and dacites), including four of the orthostats themselves.     

The Role of Faith in Historical Research

The implied strategy and the history projected in the new book of Jens Bruun Kofoed, Text and History, fails to measure up to the critical principles of both theology and science established by Thomas Acquinas' centuries' old distinction between faith and reason. An apologetic intention in Kofoed's book attempts to demonstrate that the biblical history of his evangelical faith is not unreasonable. Thomas Thompson, on the other hand, thinks it is necessary to hold the line between faith and science, which St. Thomas drew some seven centuries ago. What Kofoed argues in an effort to project a history of Israel, which would be an alternative to that of the “Copenhagen school” is not science. Nor are his rules of evidence those that the world of secular history requires. Led by an apologetic rhetoric and understanding of historical argument, Kofoed's revised Århus dissertation is dominated by a critique of the “Copenhagen school,” which attempts to show that an alternative answer is not impossible. Although emphasizing the historical methods of Thompson and Niels Peter Lemche in his critique, Kofoed neglects to include in his discussion their discussions of method or, in Lemche's case, anything he has written before 1991. His understanding of their dependency on the Annales school is clearly mistaken as is his understanding of the debates about the relationship between historicity, genre and composition. Finally, his discussion of the comparative method is misleading and ill informed.     

Biblical Inspiration & Islamic Instrumental Causality: Thomas Aquinas on prophecy and the two authors of Sacred Scripture

Scripture, according to the Christian tradition, has two authors: God as the principal author and the Holy Fathers as instrumental authors. Thomas’s biblical inspiration is accomplished through instrumental causality—the theory of causal motion where the power of a principal agent works hiddenly through a lower cause to achieve an end beyond the lower cause’s natural powers. However, Thomas formulates a new account of instrumental causality by integrating Islamic causal accounts within Greek and Christian ones. After confirming that Thomas accounts for biblical inspiration with instrumental causality, I will show how Thomas’s Commentary on the Sentences of Peter Lombard explains his theory of instrumental causality pertaining to the sacraments and how it neatly fits biblical inspiration. Finally, I will demonstrate that Thomas’s formulation of instrumental causality is novel incorporating Islamic influences through Arabic sources including: the Arabic Liber de Causis, Averroes’s two sources of motion, and Avicenna’s modes of efficient causation. The paper will thereby conclude that Thomas’s explanation on how Scripture comes to be is beholden to philosophical thinkers of the Arabic tradition.     

The impossible interview with the man of the hidden biological structures. Interview by Paolo Mazzarello

This paper presents an "impossible interview" to Professor Camillo Golgi, placed in time in December 1906. The Italian Professor Golgi from Pavia has been awarded the Nobel Prize for Physiology or Medicine ex aequo with the Spanish anatomist Santiago Ramón y Cajal. Both scientists have obtained the award for their work on the anatomy of the nervous system. However, they have opposite views on the mechanisms underlying nervous functions. Golgi believes that the axons stained by his "black reaction" form a continuous anatomical or functional network along which nervous impulses propagate. Ramón y Cajal is the paladin of the neuron theory, a hypothesis questioned by Golgi in his Nobel lecture of Tuesday, December 11. After the ceremony, an independent journalist has interviewed Professor Golgi in the Grand Hotel in Stockholm. Excerpts about his education, his main scientific discoveries, and his personal life are here given (reconstructing the "impossible interview" on the basis of Golgi's original writings).     

Marine trophic levels targeted between AD 300 and 1500 on the Georgia coast,USA

The marine trophic levels targeted during Swift Creek (AD 300–700) and Savannah (AD 1200–1500) occupations at the Cathead Creek site (9Mc360) and at two sites from the Kings Bay Locality (9CAM171a, 9CAM177), coastal Georgia, USA, differ in a consistent temporal and spatial pattern. Vertebrate and invertebrate remains from these three coastal sites contain similar suites of estuarine animals. However, Swift Creek peoples at these distinct hydrological settings obtained more biomass from fishes and less from molluscs compared to the subsequent Savannah occupants. The two Swift Creek faunal collections are less rich, more diverse, and more equitable than the two subsequent Savannah collections regardless of location. Furthermore, the mean trophic level is higher in the Swift Creek collections compared to the Savannah ones at both locations. These observations apply to both biomass and Minimum Number of Individuals. These differences likely are defining characteristics distinguishing the Swift Creek and the Savannah economies. More research is needed to determine the extent to which these temporal and spatial patterns are attributable to environmental and cultural variables.     

Dying for the fatherland: Thomas Abbt's theory of aesthetic patriotism

This article aims to dissect Thomas Abbt's (1738–1766) theory of aesthetic patriotism as laid out in his On Dying for the Fatherland (1761) and his prize-essay On Mathematical, Metaphysical and Moral Certainty (1763). Aesthetic idioms, such as the emphasis on the intrinsic pleasure from the order and beauty of virtue, had been invoked throughout the eighteenth century to vindicate the morally optimistic view of humanity against the sceptical vision of an exclusively utility-centred mankind. In the post-Montesquieu debates on the moral foundations of modern politics, German-speaking authors in particular, from both republics (Switzerland) and monarchies (Prussia), appropriated the aesthetic idioms in order to reject those theories which grounded patriotism in some sort of self-interest or proclaimed it redundant in modern society. Thomas Abbt was one of the most prominent representatives of this intellectual position. Combining the general emphasis of Shaftesbury on the role of aesthetic appreciation in moral and political agency with the more specific German Baumgartenian analysis of ‘beauty’ as a central principle in human ‘empirical psychology’, Abbt argued that patriotism in modern monarchies could be grounded in an aesthetic passion of enthusiasm generated through sensuous examples of great virtue. The example of a king fighting for his country on the battlefield could inspire monarchical subjects to follow his example as well as regenerate patriotism among them. Abbt was adamant that patriotism based on aesthetic foundations had to be supported and stabilised by a pervasive patriotic culture of remembrance and emulation of dead heroes through the fine arts, as well as by a system of meritocratic honour in the army.     

Mesoglia & microglia--a historical review of the concept of mononuclear phagocytes within the central nervous system

More than a century and a half has elapsed since the first accounts of mesodermal phagocytic elements were proposed within the central nervous system. Over the intervening decades, body and substance were added to this concept through the advancement of histological techniques at the disposal of the researcher and the acute and keen-minded skills of the pathologist. Notable among these pioneering efforts were the contributions of W. Ford Robertson, Santiago Ramon y Cajal, Pio del Rio-Hortega and Wilder Penfield amongst an entire cavalcade of other noteworthy figures. The term 'mesoglia' and 'third element of the nervous system' was bestowed upon these cells towards the beginning of the twentieth century to account for their separate origins from neurons and macroglia. It was later amended by del Rio-Hortega in 1919, to 'microglia' in order to further discriminate between true mesodermal elements and oligodendrocytes, previously regarded as a component of 'mesoglia'. This particular contention sparked much controversy among del Rio-Hortega's peers and resulted in an escalation of fruitful research throughout Europe that eventually declined up to the outbreak of the Second World War. The post-war years were a period of the 'dark ages' that cast doubt on the very existence and nature of microglia, until the 'renaissance' of research was once again rejuvenated in the 1960s, by a new cohort of intrigued minds: Cammermeyer, Blinzinger, Kreutzberg and others who saw in the 'third element' the potential that is now commonly ascribed to microglia: the intrinsic immune effector cells of the CNS. It is now universally accepted that microglia are involved as the first line of rapid defence in any pathology of the nervous system, and as such, present a diagnostic tool for the neuropathologist. Although our knowledge of microglia stems from an extensive body of work conducted over the last two decades, much of the earlier work (pre-1960s) has remained somewhat obscure. This is partly accountable due to the limited availability of translated works, and additionally to the lack of a compendium of these articles. This paper will present a comprehensive overview of the pioneering research on mononuclear phagocytes within the central nervous system, which has direct bearing on our present-day understanding of the concept of microglia.     

Royal authority versus corporate sovereignty: the Levant Company and the ambiguities of early Stuart statecraft

The ambassadorship of Thomas Bendish (1646–1660) to the Ottoman Porte was a period of turmoil that saw the arrest and imprisonment of his predecessor, Sackville Crowe, and the arrest and subsequent beheading of a usurper, Henry Hyde. This crisis in Turkey coincided with the domestic crisis of the English Civil War, which plunged the English state into chaos. This article uses the Bendish/Crowe/Hyde affair to analyse the relationship between state and trading company in order to gain a deeper understanding of how the early modern economic and state-building system of mercantilism was made. The article will show that mercantilism was, in the words of Phil Stern, an “awkward alliance” where merchant and state required one another while remaining suspicious of the other’s motives and authority.     

The impossible interview with the man of the neuron doctrine. Interview by Edward G Jones

This paper follows the form of that by Mazzarello that precedes it (Mazzarello, 2006) and presents an imaginary interview with Santiago Ramón y Cajal in December 1906. A few days earlier Cajal had been awarded the Nobel Prize for Physiology or Medicine, an award that he shared equally with Professor Camillo Golgi. Golgi had been recognized for his work as a pioneer into investigations of the nervous system, primarily on account of his discovery of the "black reaction" of silver chromate impregnation of whole nerve cells and their processes. Cajal had been recognized for his implementation of that method and for laying with it the foundations of what was to become modern neuroanatomical science. Paradoxically, the two awardees had been led by their researches to diametrically opposed views of the organization of the nervous system. Golgi believed in a continuous network of axons that formed the basis of all the integrative properties of the nervous system, while Cajal had provided the information that led to the formulation of the neuron doctrine that saw the nervous system as being made up of chains of discontinuous cells joined by polarized functional contacts that we now call synapses. The paper takes the form of an interview with Professor Cajal in the Grand Hotel Stockholm. His responses to questions posed by the imaginary interviewer are all taken from Cajal's own writings.     

Etappen auf dem Weg zu einer Geschichte der Pflanzenzüchtung. Überlegungen aus Anlaß eines Buches von Thomas Wieland

Thomas Wieland's book is the first survey on the history of scientific plant breeding in Germany from 1889 to 1945. There are two mainlines of analysis: (1) The transformation of an agricultural practise of peasants into an academic discipline of scientists and (2) the importance of political arguments for this process of scientification. Most of the time Wieland's methods to present his thesis are exemplary: either as biographies or as breeding project histories. So he can write about a great diversity of aspects; but from his point of view – the discipline history as applied science – he cannot show the great importance of economic forces controlling plant breeding. This short article will not diminish the high value of Wieland's book. My aim is only to outline some desiderata for a history of plant breeding which is not yet written.     

MESOGLIA & MICROGLIA – A Historical Review of the Concept of Mononuclear Phagocytes Within the Central Nervous System

More than a century and a half has elapsed since the first accounts of mesodermal phagocytic elements were proposed within the central nervous system. Over the intervening decades, body and substance were added to this concept through the advancement of histological techniques at the disposal of the researcher and the acute and keen-minded skills of the pathologist. Notable among these pioneering efforts were the contributions of W. Ford Robertson, Santiago Ramon y Cajal, Pio del Rio-Hortega and Wilder Penfield amongst an entire cavalcade of other noteworthy figures. The term ‘mesoglia’ and ‘third element of the nervous system’ was bestowed upon these cells towards the beginning of the twentieth century to account for their separate origins from neurons and macroglia. It was later amended by del Rio-Hortega in 1919, to ‘microglia’ in order to further discriminate between true mesodermal elements and oligodendrocytes, previously regarded as a component of ‘mesoglia’. This particular contention sparked much controversy among del Rio-Hortega’s peers and resulted in an escalation of fruitful research throughout Europe that eventually declined up to the outbreak of the Second World War. The post-war years were a period of the ‘dark ages’ that cast doubt on the very existence and nature of microglia, until the ‘renaissance’ of research was once again rejuvenated in the 1960s, by a new cohort of intrigued minds: Cammermeyer, Blinzinger, Kreutzberg and others who saw in the ‘third element’ the potential that is now commonly ascribed to microglia: the intrinsic immune effector cells of the CNS. It is now universally accepted that microglia are involved as the first line of rapid defence in any pathology of the nervous system, and as such, present a diagnostic tool for the neuropathologist. Although our knowledge of microglia stems from an extensive body of work conducted over the last two decades, much of the earlier work (pre-1960s) has remained somewhat obscure. This is partly accountable due to the limited availability of translated works, and additionally to the lack of a compendium of these articles. This paper will present a comprehensive overview of the pioneering research on mononuclear phagocytes within the central nervous system, which has direct bearing on our present-day understanding of the concept of microglia.     

The great war and the french people

Thomas Hobbes's theory of action seems to give up on the idea that actions are ‘up to us’. Thomas Pink has argued that this counter-intuitive stance should be understood as the implication of his radical assault on the scholastic Aristotelian model of action. Hobbes rejects the existence of the immaterial soul. This means that he must also reject the existence of so-called elicited acts of the will, which form the primary locus of human agency. In this paper an alternative interpretation is presented. It is argued that Hobbes's fundamental disagreement with the scholastic tradition is not over the existence of elicited acts of the will but over scope and productiveness of mechanical explanation. Hobbes aims to give an account of human actions as in our control and as ‘up to us’ while at the same time applying and defending his mechanical mode of analysis. This paper contributes to the contextualisation of Hobbes's views and furthers our understanding of his theory of action.     

The substance of sexual difference: change and persistence in representations of the body in eighteenth-century England

The claims of Thomas Laqueur for a shift from a one-sex to a two-sex model of sexual difference are incorporated into many recent histories of gender in England between 1650 and 1850. Yet the Laqueurian narrative is not supported by discussions of the substance of sexual difference in eighteenth-century erotic books. This article argues that different models of sexual difference were not mutually exclusive and did not change in linear fashion, but that the themes of sameness and difference were strategically deployed in the same period. Thus, there was an enduring synchronic diversity which undermines claims for linear transformation.     

The economic of agricultural land tenure

This article sheds new light on the interesting but little-studied figure of Thomas Scott of Canterbury (1566–1635). In presenting Scott's ideas I will modify the interpretation laid out by Peter Clark whose groundbreaking study, ‘Thomas Scott and the Growth of Urban Opposition to the Early Stuart Regime’, is still the only secondary source that pays detailed attention to Scott and his thought, especially his religious opinions. The necessity to revisit Clark's interpretation of Scott's place within the political and doctrinal debates of early Stuart England stems from the conviction that his political work and his ideological stances deserve more subtle attention. Most importantly, they were part of the emerging reaction against the policies of the first two Stuart Kings which can be labelled ‘country patriotism’. Finally, the elucidation of Scott's writings will provide a novel insight into an early configuration of English national identity.