A Review of: “Michael Hagner,Geniale Gehirne. Zur Geschichte der Elitegehirnforschung”

Charcot and Pasteur were scientific contemporaries, but their relationship has not been extensively studied. We analyzed available source documents from the Charcot Library, Bibliothèque Nationale, Institute Pasteur, and Pasteur Library. These documents demonstrate that in spite of geographical proximity, international and local recognition, Charcot and Pasteur largely pursued their careers independent of one another. Although the Paris scientific climate was one of active debate, Pasteur's and Charcot's interactions remained distanced but mutually respectful and did not descend into rivalry or contention. With different primary interests and different etiological views, side by side, they exemplified two models of French medicine at the close of the nineteenth century: medical scientist and scientific physician.     

Broca’s faculté du langage articulé: Language or Praxis?

De Oliveira-Souza, Moll, and Tovar-Moll (this issue) historically reevaluate that Paul Broca’s aphemia should be considered as a kind of apraxia rather than aphasia. I argue that such a claim is unwarranted, given the interpretation of the faculty of speech Broca derived from his predecessors, Jean-Baptiste Bouillaud and Franz Joseph Gall, and also with a view on the then generally held opinion that the terms aphémie and aphasie were synonyms. I will discuss evidence that patients such as Leborgne, producing only very few words or syllables, suffer from a global aphasia, affecting all modalities, despite Broca’s statement that Leborgne’s comprehension was intact. I also point to Broca’s claim that the faculty of speech, located in the left anterior hemisphere, is independent from hand preference because it is an intellectual and not a motor function, and to his statement that the cerebral convolutions are not motor organs. I finally contend that, in order to determine whether a given language problem should be labeled as aphasia or apraxia, it is crucial to first be clear on the components of old and new models of language production.     

Broca’s Aphemia: The Tortuous Story of a Nonaphasic Nonparalytic Disorder of Speech

Broca coined the neologism “aphemia” to describe a syndrome consisting of a loss of the ability to speak without impairment of language and paralysis of the faciolingual territories in actions unrelated to speech, such as protruding the tongue or pursing the lips. Upon examining the brains of patients with aphemia, Broca concluded that the minimum possible lesion responsible for aphemia localized to the posterior left inferior frontal gyrus and lower portion of the middle frontal gyrus. A review of Broca’s writings led us to conclude that (a) Broca localized speech, not language, to the left hemisphere, (b) Broca’s aphemia is a form of apraxia, (c) Broca’s aphemia is not, therefore, a terminological forerunner of aphasia, and (d) Broca was an outspoken equipotentialist concerning the cerebral localization of language. Broca’s claim about the role of the left hemisphere in the organization of speech places him as the legitimate forebear of the two most outstanding achievements of Liepmann’s work, namely, the concepts of apraxia and of a left hemisphere specialization for action.     

Do body proportions among Jomon foragers from Hokkaido conform to ecogeographic expectations? evolutionary implications of body size and shape among northerly hunter‐gatherers

This study documents and interprets adaptive postcranial morphology among prehistoric Jomon period foragers from Hokkaido, Japan (HKJ). The Hokkaido climate is differentiated from other Japanese islands by freezing winters with sea‐ice accumulation in the northern regions. Increased brachial and crural indices are, however, observed among HKJ foragers, while body mass (BM) has not yet been estimated for these groups. Based on previous observations and paleoclimatic reconstructions, it was predicted that increased BM and increased distal relative to proximal limb lengths would typify HKJ foragers. Similar BM was observed between HKJ foragers and groups from colder environments. Intralimb indices do, however, suggest similarity between HKJ foragers and groups from high‐latitude, warm environments. It is likely that HKJ foragers retained cold‐derived BM in association with Pleistocene migrations to Hokkaido via Northeast Asia. That is, enlarged BM among HKJ foragers is associated with long‐term evolution in a colder environment. Relatively elongated distal limbs may represent morphological response to a slightly warmer environment. Following migration to Japan from a colder environment, elongation of distal limb segments resulted in elevated brachial and crural indices. Relatively elongated distal appendages may also reflect positive nutritional status as HKJ people experienced lesser rates of systemic stress than other Jomon groups. It is also possible that elongated distal relative to proximal limbs are associated with neutral mutation and genetic drift. This interpretation suggests a neutral mutation associated with relative limb length in some HKJ ancestor with subsequent spread of this allele through isolation and drift. Ontogenetic and temporal studies of intralimb indices among Jomon people are necessary to further evaluate these interpretations. Copyright © 2009 John Wiley & Sons, Ltd.     

Protagonists and politics in the Italian women's movement: a reflection on the work of Annarita Buttafuoco

This article retraces Annarita Buttafuoco's work as a historian of the women's political movement in Italy through a brief survey of her essays and books. These covered more than two centuries of history, ranging from the echoes of the French Revolution in Italy and the constitution of the Jacobin Republics to the struggles for female suffrage and emancipation in the liberal era down to the period after the Second World War and the founding of the Italian Republic. Emphasizing the originality of both the sources and the methodological approaches she used, the article offers a critical appreciation of Annarita Buttafuoco's research and her role in organizing and shaping collective research projects. It is focused on three specific issues: the history of women as conscious historical subjects, the history of women's political movements not only in their social and political contexts but also in relation to institutional networks and the practices of citizenship.     

Historical Development of the Dopamine Hypothesis of Schizophrenia

This review examines the history of discoveries that contributed to development of the dopamine hypothesis of schizophrenia. The origin of the hypothesis is traced to the recognition that neuroleptic drugs interfere with brain dopamine function. This insight was derived from two distinct lines of research. The first line originated from the discovery in 1956 that reserpine depletes brain serotonin. This finding resulted in a sequence of studies that led to the discovery that brain dopamine is involved in neuroleptic-induced extrapyramidal motor disturbances. The second line of research was aimed at determining the mechanism of action of psychomotor stimulants. This research produced evidence that stimulants directly or indirectly activate brain dopamine receptors. Because nonreserpine neuroleptics such as chlorpromazine block stimulant-induced movement, these findings suggested that neuroleptics were dopamine antagonists. Most previous accounts of the development of the dopamine hypothesis of schizophrenia emphasize the first line of research and ignore the second.     

From Active Young Explorers to Passive Young Consumers: The Commercialization of Canada's OWL Magazine

This article provides a content analysis of OWL magazine, a popular Canadian children's periodical published initially by a non-profit organization and, after 1997, by a for-profit corporation. Researchers examined issues of OWL from 1982, 1992, and 2002 to assess changes in the magazine in response to commercial ownership. Quantitative and qualitative methodologies were used to show how OWL has shifted from a primarily science and animal-themed magazine to a general interest “consumer” magazine for children with features like video game reviews. This shift from 1982 to 2002 is discussed within larger changes in Canadian children's commercial media and marketing. Canadian and American children's commercial media “boomed” during the 1980s and 1990s, placing additional pressure on OWL to incorporate content that met advertisers' interests and emerging consumerist outlook of Canadian children. We conclude by discussing how this research informs ongoing theoretical debates about the commercialization of childhood.     

Burial of an early 19th century suicide in the crypt of St Bride's church,fleet street

A skull from the St Bride's collection showing evidence of gunshot wounds is described. The position of the wounds suggests that they were self-inflicted. Examination of historical records confirms that the individual committed suicide by shooting himself in the mouth. The fact that this individual was buried in the crypt of St Bride's church in 1821 is discussed in relation to early 19th century attitudes to suicide.     

Women's history in Italy (nineteenth and twentieth centuries)

This essay surveys the development of women's history in Italy since its origins, examining the principal questions that have driven research and debate from the 1960s to the present, the ways in which women's history in other countries (notably the US) has been influential in Italy, the impact of women's history on other branches of historical research in Italy and its place — or rather lack of place ‐ in Italian universities.     

Innovations of modern Chinese history studies since reform and opening-up

This paper reviews new developments in the study of modern Chinese history since 1979, especially key questions in modern Chinese history, together with innovations in content, structure and research methods. These new developments reflect the broadening of academic exchanges with foreign countries, the initiation of reforms, the influence of the modernization process, and far-reaching innovations in the discipline of modern Chinese history studies since the reform and opening-up of China.     

Broca and Charcot’s Research on Jacques Inaudi:The Psychological and Anthropological Study of a Mental Calculator

In the nineteenth century, French scientific institutions became interested in young “mental calculators,” arithmetical prodigies able to quickly and accurately perform complex mental calculations. The first scientists to study mental calculators were phrenologists who sought to prove the existence of a calculating organ in the frontal lobe. Paul Broca introduced one such mental calculator, Jacques Inaudi, to the Anthropological Society of Paris in 1880. Broca attributed extraordinary faculty for mental calculation to memory functioning (the psychological hypothesis) rather than physiological difference (the phrenological hypothesis). In 1892, prominent French Academy of Sciences member Jean-Martin Charcot produced a noteworthy study of Inaudi on the organization’s behalf. Charcot observed that Inaudi called upon auditory memory rather than visual memory in his mental calculations, unlike most mental calculators who preceded him. Like Broca, Charcot was skeptical of the phrenological hypothesis, though he noted that Inaudi’s skull was markedly plagiocephalic. Interestingly, anthropological examination of Inaudi is consistent with the themes of modern cognitive neuroscience. Thus, Charcot seems to have anticipated present research on the localization of mental calculation and memory for numbers.     

Making the Brain Plastic: Early Neuroanatomical Staining Techniques and the Pursuit of Structural Plasticity, 1910–1970

The concept of neuronal plasticity is widely used, but seldom defined in the neurosciences. It can signify many different occurrences, such as structural alterations of axons and dendrites (Cotman & Nadler, 1978), behavioural adaptations (Rosenzweig & Bennett, 1996), or physiological changes in synapse formation (Martin et al., 2000) at different stages of health and disease. Although there is such a wealth of research from many disciplines, the neuroanatomical aspects of plasticity are the focus of this paper. It seeks to illuminate the evolution of different concepts of plasticity concerning the structure and circuitry of the central nervous system (CNS). Early modern morphological research on de- and regeneration phenomena in the 19th- and early 20th-century is well documented. These studies, however, almost exclusively concentrated on the peripheral nervous system (PNS). It was one of the major contributions of Santiago Ramón y Cajal (1852–1934), that he applied the concept of regenerative capacities to the CNS. But the term plasticity seemed to have disappeared for about two decades after his death. The ensuing comeback of the expression may be attributed, at least in part, to new neuroanatomical staining and tracing methods. The pursuit of these techniques will serve as a guidepost through varying approaches in different times: It was the 1950s which seemed to spawn the time for new departures in structural investigations of neuronal plasticity.     

Introduction: space,place and the geographies of women's caregiving work

The vast majority of caregivers, whether formal or informal, paid or unpaid, are women. Health care restructuring across the West, inspired by a shift from the welfare to neoliberal state, has greatly impacted caregiving. The idea for this collection arose as a result of a special paper session on the geographies of caregiving, held as part of the Association of American Geographers Meeting (Chicago, 2006). In hearing the papers presented, it became clear that geographers are engaged in interesting and innovative research in this area, much of which involves women's caregiving work in particular. As both unpaid informal family caregiving and paid formal practitioner-provided care are mainly addressed in this collection, they are briefly discussed in this editorial. This is followed by a discussion of the geographical contributions to the growing caregiving literature, which provides the foundation for an overview of ongoing and new research directions. The four articles that make up this special issue are then reviewed in brief. Finally, we identify issues that cut across all four articles, leading to a discussion of future research directions.     

The first archaeological example of Freiberg's infraction

Freiberg described a condition in which collapse of the juvenile second metatarsal head gave rise to localized pain and swelling.¹ This eponymous disease is traditionally classed as one of the osteochondroses, a group of disparate lesions that typically manifest as destruction of an immature epiphysis. A medieval second metatarsal is presented, which by osteological and radiological examination is diagnostic of Freiberg's infraction. This is the first reported archaeological example of the condition.