Lung cancer, chronic disease epidemiology, and medicine, 1948-1964

Beginning in the early 1950s, a series of epidemiological, biochemical, pathological, and animal studies demonstrated a link between cigarette smoking and lung cancer. A number of reputable scientists challenged these findings, but for a variety of reasons, including the behavior of the tobacco industry, historians have assumed that these objections were insubstantial and disingenuous. Viewing these objections in scientific and medical perspective, however, suggests that there was a legitimate and reasonable scientific controversy over cigarette smoking and lung cancer in the 1950s and early 1960s. That controversy had important consequences. A new chronic disease epidemiology emerged, transforming the role and importance of epidemiology to medical research. This new epidemiology supplemented Koch's postulates, establishing a statistical method that allowed for linking environmental factors to the etiology of chronic diseases. The 1964 report to the surgeon general, Smoking and Health, represented the denouement and codification of these developments. This reexamination of the scientific controversy over smoking in the 1950s and early 1960s provides an important context for understanding the subsequent public relations battles between the tobacco industry and public health after 1964.     

A Sixteenth-Century Wealden Blast Furnace: A Report on Excavations at Panningridge,Sussex, 1964-1970

Abstract

The excavation recovered evidence for two periods of iron smelting; there were substantial surviving structures from a blast furnace thought from documentary sources to have produced pig-iron from 1542 until at least 1563 and, superimposed, indications of a later furnace built with major changes in layout at some time after 1563 but abandoned well before 1611. It was possible to compare, in particular, the application of water-power in the two periods and to sample ore and cast iron. The features of the first furnace could be related to references in surviving account books, and thus a yardstick may be offered for future fieldwork on undocumented furnaces of the period.     

Killing Kith and Kin: The Viability of British Military Intervention in Rhodesia, 1964-5

This article uses correspondence from former members of theRhodesian security services, recent oral testimony from Britishpoliticians and civil servants, and newly available documentaryevidence from archives around the world, to re-examine the viabilityof British military intervention in Rhodesia during 1964 and1965. It argues that the military and political obstacles tothe use of force cited at the time and since have been grosslyexaggerated. This article argues that with sufficient resolve,the Labour government led by Harold Wilson could have used forcein an attempt to prevent or end Rhodesia's Unilateral Declarationof Independence of 11 November 1965. This might have offereda possible solution to one of the most protracted and embarrassinginternational problems that confronted successive British governmentsduring disengagement from Empire.     

The Spatial Dynamics of Poliomyelitis in the United States: From Epidemic Emergence to Vaccine-Induced Retreat, 1910-1971

This article seeks to advance an understanding of the spatial dynamics of one of the great emergent viral diseases of the twentieth century-poliomyelitis. From an apparently rare clinical condition occurring only sporadically or in small outbreaks before the late nineteenth century, poliomyelitis had, by the early 1950s, developed into a globally distributed epidemic disease. But, from 1955, continued growth was suddenly and dramatically reversed by the mass administration of inactivated (killed) and live (attenuated) poliovirus vaccines. After almost half a century of vaccine control, the world now stands on the brink of the global eradication of the disease. Against this background, the article draws upon information included in the U.S. Public Health Service's Public Health Reports and the U.S. Centers for Disease Control and Prevention's Morbidity and Mortality Weekly Report to examine the spatial dynamics of poliomyelitis during the phases of epidemic emergence (1910-1955) and vaccine-induced retreat (1955-1971) in the United States. It is shown that epidemic emergence was accompanied by shifts in the spatial center of activity from early diffusion poles in the northeastern states, to the western seaboard, and then finally to cover all the states of the Union. This was accompanied by accelerating epidemic propagation. The introduction of mass vaccination from the mid-1950s realigned spatial transmission of the disease, producing increased spatial volatility in the geographical center of activity and heightened dependence of epidemic outbreaks upon endemic reservoirs in the most populous states. Finally, the empirical results are generalized to suggest that the emergence and reemergence of many infectious diseases is a distinctively geographical process.     

Amnesty International in Crisis, 1966-7

During 1966, Amnesty International, which had been establishedin 1961 to campaign for the release of ‘prisoners of conscience’,was shaken by a severe internal crisis. It was alleged thatAmnesty had been penetrated by British Intelligence agents,and that it had channelled secret British government fundingto the families of political detainees in Rhodesia. Althoughthe organization survived the crisis, it resulted in the resignationof Amnesty’s founder Peter Benenson as President, andprovoked a re-evaluation of its operational methods. This articleoffers the first detailed account of this episode, drawing onhighly significant new archival and documentary sources.     

Dynamics of Disintegration: Diaspora,Secession and the Paradox of Nation-States

Abstract. The underlying logic of an international system based on nation-states should lead to the gradual elimination of trans-national loyalties, intra-national divisions and stateless communities. Paradoxically, current realities indicate that the reverse is true, with these phenomena becoming more and more prevalent. The article proposes a comprehensive analytical framework for the study of the complex relationships between diaspora formation, secessionist (and irredentist) drives and the existing nation-state system. It traces the genesis, and the subsequent effects, of differing variants of diaspora formations and secession (irredentist) movements to the interplay between two distinct independent variables: (1) the formation and disintegration of different nation-types (ethno-focal or ideo-focal); and (2) the modus operandi of different regime-types (libertarian or authoritarian). The processes produced by these interactions generate a perennial source for the rejuvenation of old identities and the awakening of new ones, which in turn constitute an incessant challenge to the prevailing state system. Thus rather than becoming an anomalous anachronism of the past, diasporas and separatist sentiments appear to be not only an endemic feature of the international system, but a pivotal element in comprehending the direction of present and future trends in it.