Brown-Séquard and his syndrome

The contributions of Charles Edouard Brown-Séquard (1817-1894) to the advancement of medical science included his emphasis on functional processes in the integrative action of the nervous system, his discovery of the vasomotor nerves, his experimental demonstration that the adrenal glands are esential to life, and his pioneering work on hormone replacement therapy. He is best remembered, however, for his work in delineating the sensory pathways in the spinal cord. His later work on the sensory function of the cord emphasized dynamic spinal mechanisms that may well have major implications for the rehabilitation of patients with cord injuries.     

Turkish–Dutch mosques and the formation of moral subjects

This article explores how mosque spaces become everyday sites of ethno-religious subjectivation for immigrants and citizens originating from Turkey in the Netherlands. I argue that the symbolic and material constructions of mosques as simultaneously moral and moralizing spaces undergird the production of ethno-religious subjectivities through mosque-centered everyday practices. The articulation of Muslimness to Turkishness at mosques in culturally specific and gendered ways is crucial for the formation of a particular modality of the Turkish–Dutch self as moral subject. The ensuing incorporation of practices and activities that are deemed ‘secular,’ i.e. ‘cultural’ or ‘recreational’ to mosque services engenders a creative tension between the sacred and profane conceptions of mosque space. Mosque administrators and their congregations concur that recreational activities and quotidian accessibility to mosques are essential to the long term survival of Turkish–Dutch alterity, for mosques are spaces where children and youth are exposed to the performances of Turkish-Islamic morality and subjected to collective social control. However, the diversification of mosque services does not always sit comfortably with the meaning and use of mosques as sacred sites proper within a secularized framework. A creative tension between mosques as serene and pure spaces of the sacred and mosques as impure and immoral spaces of the everyday arises, as a result.     

Death of a President and his Assassin—Errors in their Diagnosis and Autopsies

On July 2, 1881, Charles Julius Guiteau shot President James Abram Garfield in the right flank. The President died because of infection produced by the unsterile fingers and probes repeatedly inserted into the wound. The major complaint of the wounded President was intractable pain in his legs and feet. This symptom failed to alert the doctors to the possibility of vertebral and spinal cord injury. Garfield died with sepsis after 80 days of intense national concern, and for the patient there was psychological, physical, and nutritional deprivation. His autopsy revealed the bullet was not in the pelvis as his doctors had expected, but adjacent to the first lumbar vertebra it had shattered. The trial and execution of Guiteau split the medical community into those that considered him insane and those who felt execution was justified. Guiteau was delusional and his brain revealed chronic inflammation and histological features suggestive of syphilis. At the time, and since, the propriety of the execution has been questioned.     

‘Seeing in the Dark’: Franz Joseph Thun and his Encyclopedia

Abstract

In the late 1790s the extravagant Bohemian aristocrat Franz Joseph Thun (1734–1801) composed a massive encyclopedia containing his wide-ranging and esoteric knowledge, which was not discovered until 2009. In this article I discuss the contents of his encyclopedia and investigate Thun’s place within the broader intellectual climate in Central Europe. I argue that Thun was an exceptional case in the Habsburg context, where scientists generally rejected outright the sort of excesses his encyclopedia contains. None the less, he became famous for his experiments with a spirit named ‘Gablidon’ and for his sessions in Mesmerism. His encyclopedia focuses on three topics: human ethics, man’s place in nature, and the sins of the French Revolution. He saw man as the middle link in the ‘great chain of being’, whose morality must be based on submission to God. Although he distanced himself from the Catholic Church, he rejected the French Revolution as an attempt to establish a state without religious basis.     

Brown-Séquard and cerebral localization as illustrated by his ideas on aphasia

Brown-Séquard's concept of localization was built on the phenomena of inhibition and dynamogenesis, constituting a dynamic system in which reflex mechanisms, that played a part not only in the spinal cord but in the brain as well, were considered of particular importance. The use of this concept is considered in Brown-Séquard's discussion of the subject of cerebral localization, and especially of aphasia. The origin and development of Brown-Séquard's ideas on aphasia from 1861 onwards are discussed, as is the part he possibly played in the transfer of knowledge from Paris to London (Broca and Jackson). In the 1870's Brown-Séquard debated on cerebral localization with Charcot before the Société de Biologie. Opposing the cluster theory of localization, Brown-Séquard developed the theory of "réseau de cellules anastomosées", a kind of network theory in which scattered cells subserving the same function are connected by nerve fibers. This was to him a plausible theory, with which he was able to explain the fact that damage in several locations may produce the same effect, and, to account for observations that some functions remain unimpaired despite extensive brain-injury. Although Brown-Séquard's arguments were not always valid, because they were based on imprecise observations, his dynamic model, nowadays, seems valuable. He influenced "anti-localizers" such as Goltz, but also Jackson and probably Von Monakow and Sherrington.     

The political will and the administrative won't? Mathieu Thomassin and his dauphins (Charles III and Louis II)

The delphinal counsellor Mathieu Thomassin composed a Breviere des anciens droys … du Dauphiné de Viennoys (c.1453) after a career of 30 years in the service of Charles III (the French king Charles VII) and Louis II (the future Louis XI). This was his first major historical text in French, but has been overshadowed by his better-known Registre delphinal, commissioned by Louis II in 1456. This article analyses the historical culture and the conception of history revealed in the Breviere. It notes how Thomassin's careful definitions of frontiers in the past and present reflect his experience of territorial disputes. History and geography are imbued with polemic, however, allowing Thomassin to override competing claims to territory or autonomy by delphinal opponents within and outside the Dauphiné. The principles set out in the Breviere were refined and extended in the Registre. However, it is unlikely that either work was ever intended for wide circulation; rather, they were written to provide ‘authentic’ texts which could be consulted primarily by other delphinal officers. As such, they reflect on occasion the divergence of views between a proto-professional administrator, with a concern for the long-term, and his preoccupied (if not dilettante) prince, much more subject to the requirements of realpolitik.