Drugs for Tropical Diseases in the Third World

Abstract

The relationship between the World Health Organization's Special Programme for reducing tropical diseases and the pharmaceutical industry is the author's main theme. The problems of malaria, schistosomiasis, filariasis trypanosomiasis – both types – leishmaniasis and leprosy are surveyed with references to their chemotherapy, the search for new drugs and possible immunity. It is concluded that existing drugs are far from perfect, but untll better ones have been discovered, they represent the best treatment for most of the diseases reviewed.     

Preparing Geography,Earth and Environmental Science (GEES) Students for Employment in the Enterprise Culture

Maps and related graphics are important means of representing key issues in development education and related themes. This paper examines the use of world maps in materials used in teaching development in higher education and concludes that many are not 'fit for purpose'. Many of these maps create false connotations, which can lead to misleading understandings of key issues.     

Urban experimentation & sustainability transitions

ABSTRACT

This special issue deals with various research questions regarding the impact of urban experimentation on transitions towards sustainability in different industries and sectors. Cities have been identified to play a vital role for sustainability transitions. Not only are they places with an increased urgency for change, but they also bring about many current sustainability initiatives and interventions. This special issue focuses on investigating the relationship between urban experimentation and institutional change. The articles shed light on various characteristics of urban environments that influence experimentation and potentially lead to institutional change and thus elaborate on some of the distinct mechanisms through which urban experimentation can lead to broader systemic changes.     

From the editors

From a background in documenting traditional Sami knowledge of major predators, the author discusses the conflict of interests between Sami reindeer herding and Swedish environmental policy on the matter of governmental administration of predators. The author argues that a recognition of the fact that different cultures see and relate to nature and the countryside from different standpoints and within different frames of reference is missing in today's debate in Sweden. According to the author this could lead to a situation of eco‐colonialism if Sami experiences and apprehensions are not taken into account in Swedish environmental policy.     

Historiographical Myth,Discipline, and Contextual Distortion

Summary

Although academic disciplines are given to mythologising their own histories, corrective historicisation is no straightforward matter. Anachronisms are most difficult to avoid where our own tacit understandings of the world are used to help structure contexts that are themselves often unstable and indeterminate. This is often the case in attempts to relate agents and propositions to a context of pre-existing problems. Propositions and concepts that are the result of satiric reduction, or unintended consequence, disrupt narrative sequences that lead directly and neatly to present disciplinary identities.     

Interdisciplinarity as critical Inquiry: Visualizing the Art/Bioscience interface

Abstract

Much˙ of the physiology of human cells is controlled at their surfaces. Our knowledge is based on an interdisciplinar:r approach involving research in subject areas ranging from physics to medicine. In this review, the structure and function of cell surfaces, their turnover and their role in cell division is described. The concept of cell sulrface diseases is introduced and discussed. The conclusion is reached that further knowledge of cell surfaces will lead to better treatment of many common diseases.     

The Risk of Technology

Abstract

To remain competitive in the present technological revolution we must recognize that our traditional type of university education is not appropriate to more than a fraction of those entering higher education. Ageing university staff and a sad waste of skill of junior researchers in the United Kingdom, Europe and Ihe United States are the symptoms which should encourage a diversity in universities, some to specialize in teaching, others in research, and thus lead to a hierarchy of universities.     

Polesworth: a north Warwickshire country pottery

Abstract

In 1986 excavations for house foundations at Polesworth in northern Warwickshire (SK 263 980) uncovered a pottery waster dump. Fine wares, lead glazed and unglazed coarsewares, including a number a horticultural vessels, were recovered, together with kiln furniture. An archaeological excavation adjacent to the construction site revealed stratigraphy relating to the backfilling of a clay pit with potting waste early in the 18th century. Documentary and other evidence shows that the pottery was in production from the late 17th to early 19th centuries.     

Reviews

Abstract

It is widely held that the hazardous nature of their occupation made miners unusually susceptible to the appeals of evangelical religion. Data relating to Methodist chapel membership and attendance and to Easter communication in the Church of England are presented for overlapping time periods in three contrasting mining areas of County Durham. These show that the lead miners of Upper Teesdale were exceptionally Methodist; the colliers of the Deerness Valley and the east coast villages of the Easington area were not. The differences between the three areas are explained by the interaction of cultural and social-structural features.     

Royal Scottish Geographical Society April 1948

ABSTRACT

Land use in Scotland's countryside is currently an issue of major public concern, largely because of a sea-change in agricultural policy which seemslikely to lead to the withdrawal of some land from agricultural use. In addition, there has been concern about the scale of upland afforestation, about land availability for housebuilding, and about claims on land for conservation and for rural development. This article provides an overview of these current landuse issues in Scotland.     

PARIS London: One Hundred and Fifty Years of Site Preservation

Abstract

This paper outlines the history of preservation in situ as practised in London over the last hundred and fifty years. It touches upon the early development of the City of London and the destruction of significant remains, which gradually lead to a heightening of sensitivities and public concern for preservation, particularly of built fabric such as the Roman defences. The role of cases such as the Walbrook Mithraeum and Rose Theatre are discussed, both influential in changing the relationship between development and archaeology. The paper concludes by noting how much we have learnt from past mistakes, but notes that more can be done to make these sites more accessible.     

RECALCULATING MOUND VOLUME AT MOUNDVILLE

Abstract

Volume is a critical measure in quantifying differences among earthen mounds. Previous methods for measuring mound volume are prone to error by oversimplifying the symmetry of earthworks. However, the wide availability of contouring software has made it simpler to calculate volume. The results obtained using a computerized technique referred to as the gridding method are compared with previous mound volume estimates at Moundville. The outcome shows that volumes calculated using the gridding method are much smaller than the original estimates. Inflation of the volume of earthen mounds may lead to misrepresentations regarding the degree of sociopolitical organization that existed at Moundville and at other prehistoric mound-building societies in the southeastern United States.     

Migration strategies and occupational outcomes of southern Italian graduates

Abstract

The aim of this work is to analyse whether internal migration of graduates is an efficient strategy for addressing scarce occupational opportunities in southern Italy. Analysis of data on the southern graduate population in 2004 shows the rise of a new aspect of social discrimination for recent graduates in the process of transition to the labour market. In fact, the probabilities of adopting different strategies of geographical mobility are not homogeneously distributed, but they change on the basis of available family resources. This differentiation has an impact on labour market outcomes, modifying strategies and ways that lead the transition towards employment.     

Opportunities for exploitation of magnetic materials in an energy conscious world

Abstract

It is not generally recognised that in terms of both value and volume, global production of magnetic materials far exceeds that of semiconductors. What is also not realised is that about a twentieth of all energy generated in industrialised societies is wasted as magnetic losses in electromagnetic cores. Such losses could be significantly reduced if full advantage were taken of recent developments in magnetic materials. This paper reviews major discoveries of new hard and soft magnetic materials, improved manufacturing processes, and ways in which more knowledgeable use can be made of materials to capitalise on enhanced magnetic properties. Better choice and application of commercially available materials in devices such as motors, transformers, actuators, and sensors can lead to tremendous energy savings. Development of new and traditional magnetic materials based on better understanding of magnetisation processes will lead to even more substantial energy savings, significantly improved product performance, and new applications which would benefit most sectors of industry.     

A case for lead-glaze experimentation by late eighteenth-century Catawba using portable X-ray Fluorescence (pXRF)

ABSTRACT

Recent research has demonstrated that Catawba ceramic practices changed abruptly and dramatically after 1759 following a devastating smallpox epidemic and subsequent community relocation. Pottery from the historically documented Catawba town of Old Town and others indicate potters adopted new techniques and styles as they adjusted to new economic and social conditions, including copying European vessel forms, experimenting with new ceramic paste recipes, and utilizing new decorative motifs. The identification of four lead-glazed sherds on otherwise Catawba-looking pale-bodied paste raises the possibility that Catawba potters may have also experimented with lead glazing. This paper presents the results of an elemental analysis of nearly 70 ceramic samples using pXRF and multivariate statistical techniques to identify patterns of production within pale-bodied colonowares. The results indicate that the glazed pottery fragments were made with elementally similar clay used by Catawbas in the Twelvemile Creek locality. I argue that in addition to modifying nearly every aspect of their ceramic repertoire, at least one Catawba potter experimented with lead glazing, providing further insights into the emergent Catawba pottery trade.     

Democratisation and the British Empire

ABSTRACT

This article responds to the statistically established finding in democratisation studies that British rule seems to have been good for the survival of democracy in its former empire, and that the longer a nation spent under British rule, the likelier it is to have sustained democracy since independence. This is a finding which puzzles political scientists because they think of democracy and empire as opposites. The article considers the uses made of democratic innovation by the British and the responses anti-colonial nationalists made to the offer to ‘lead them to democracy’. It places democracy and empire in a different, more complex relationship. It also considers the contribution of anti-colonial protest to the working of democracy.     

The Growth Cone as Seen Through Cajal's Original Histological Preparations and Publications

Abstract

Multiple sclerosis (MS) was first presented in a clinical setting in 1838. In this paper the presentation and treatment of a transient hemiparesis in a drummer in 1789 is discussed. This may have been an early case of MS and presents evidence against the theory that MS is an infectious disease beginning in the 19th century.     

‘We visit the colo towns … when it is safe to go’: Indigenous Adoption of Methodist Christianity in the Wainibuka and Wainimala Valleys,Fiji, in the 1870s

ABSTRACT

The Methodist mission in Fiji was from its inception maritime in nature and was slow to move into the interior of the largest island, Viti Levu. In the 1870s, only two European missionaries ministered to most of Viti Levu, leaving the greater part of evangelism and teaching in the hands of Fijian native ministers (talatala itaukei) and particularly teachers (vakavuvuli). Using evidence from mission and secular travellers in the eastern highland areas of the Wainimala and Wainibuka valleys, this paper suggests that the measles epidemic of 1875, while horrific in its direct effects, did not lead to widespread rejection of Christianity in the valleys of eastern Colo. Rather, Methodism progressed slowly, developing in ways that maintained Fijian priorities and customary practices, and the forms of education and fundraising adopted included Indigenous modes of learning and exchange.