Smell: A Challenge to Interdisciplinary Science

Abstract

The sense of smell remains an intractable problem and a challenge to interdisciplinary sciences. Not only are there no primary odors or periodic table of scents but there are no satisfactory numerical identifications by visual, auditory or somesthetic methods of measurement. A particle-wave relation may exist to reconcile the correlation of many odors with infrared spectra, but the vibrational theory of smell is currently out of fashion. Structure-activity relationships have been studied in human olfactory processes and have yielded perfume compounds of great value to commerce. Research on pheromones is intense to control insects, and the further study of human pheromones may even reveal an unsuspected communications system. At present, interdisciplinary sciences can well be guided by the artist-perfumer for what seems a millennium of research in molecular biology.