Tracking tuberculosis in the past: the use of genealogical evidence |
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| Authors: | Sherry Olson,Kevin Henry,Michè le Jomphe,Kevin Schwartzman,Paul Brassard |
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| Affiliation: | 1. Department of Geography, McGill University, 805 rue Sherbrooke ouest, Montreal, Québec, Canada H3A 2K6;2. Geography & Urban Studies, Temple University, Gladfelter Hall, 1115 W. Berks Street, Philadelphia, PA 19122, USA;3. Projet BALSAC, Université du Québec à Chicoutimi, 555, boulevard de l''Université, Chicoutimi, Québec, Canada G7H 2B1;4. Respiratory Epidemiology Unit, Montreal Chest Institute Room K1.23, 3650 St. Urbain, Montréal, Québec, Canada H2X 2P4;5. Department of Medicine, Division of Clinical Epidemiology, McGill University Health Centre, R4-29, 687 Avenue Des Pins Ouest, Montreal, Quebec, Canada H3A 1A1 |
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| Abstract: | A series of mutations of tuberculosis, present in the 1990s among elderly persons in the Province of Quebec (Canada), is interpreted as the outcome of a suite of three episodes of high mobility. The most recent is the rapid urbanization of the 1950s. In the 1840s exceptional mobility was a feature of frontier settlement and exploitation of timber. Unusual mobility in the 1750s and 1760s was associated with wartime conditions of the British conquest of Quebec and re-settlement of Acadian refugees. The scenario was developed from cartographic analysis (using geographic information systems), genealogies of the human hosts, and molecular genetics of the bacterium. |
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| Keywords: | Tuberculosis Quebec Acadia Forest history Epidemiology Genealogy Drug resistance |
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