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The survival of biochemical information in archaeological bone
Authors:R. E. M. Hedges  Carmichael J. A. Wallace
Affiliation:1. Research Laboratory for Archaeology and the History of Art, 6 Keble Road, Oxford, OX1 3QJ, UK;2. Laboratory of Molecular Biophysics, Department of Zoology, South Parks Road, Oxford OX1 3QJ, UK
Abstract:The paper gives a review of the advantages of genetic information potentially available from surviving molecules (especially proteins) in bone. Survival of such information depends on degradative processes during burial. Conventional protein chemical and immunochemical investigations on various organic components remaining in buried archaeological bone are described. The results provide information on the chemistry of collagen degradation, and indicate that polymorphic macromolecules survive at too low a concentration to be easily detectable.
Keywords:Bone   Collagen   Protein   Amino-acids   Immunology   Genetics
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